KDU691
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- $59 - $2492
- Product name: KDU691
- CAS: 1513879-19-0
- MF: C22H18ClN5O2
- MW: 419.86
- EINECS:
- MDL Number:
- Synonyms:KDU691;KDU691;KDU-691;KDU 691;1513879-19-0;KDU691 >=98% (HPLC);Imidazo[1,2-a]pyrazine-6-carboxamide, N-(4-chlorophenyl)-N-methyl-3-[4-[(methylamino)carbonyl]phenyl]-;PI4 kinases,blood,Inhibitor,liver,Phosphatidylinositol 4 kinases,ring-stage,falciparum,Parasite,plasmodium,schizonts,gametocytes,KDU 691,PI4K,KDU-691,inhibit,KDU691,stage
22 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- Axon Medchem
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3122EB
- Product descriptionCID90157166
- Packaging25mg
- Price$876
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging1mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging5mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging10mg
- Price$207
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging25mg
- Price$394
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging50mg
- Price$512
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging100mg
- Price$666
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging250mg
- Price$995
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging1g
- Price$2492
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2845
- Product descriptionKDU691 99%
- Packaging25mg
- Price$555.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29019
- Product descriptionKDU691
- Packaging1mg
- Price$59
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29019
- Product descriptionKDU691
- Packaging5mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29019
- Product descriptionKDU691
- Packaging10mg
- Price$336
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29019
- Product descriptionKDU691
- Packaging25mg
- Price$699
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0012775
- Product descriptionKDU691 99.56%
- Packaging5mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0012775
- Product descriptionKDU691 99.56%
- Packaging10mg
- Price$250
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3122EB | CID90157166 | 25mg | $876 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 1mg | $59 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 5mg | $117 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 10mg | $207 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 25mg | $394 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 50mg | $512 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 100mg | $666 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 250mg | $995 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 1g | $2492 | 2021-12-16 | Buy |
| Axon Medchem | Axon2845 | KDU691 99% | 25mg | $555.5 | 2021-12-16 | Buy |
| Cayman Chemical | 29019 | KDU691 | 1mg | $59 | 2024-03-01 | Buy |
| Cayman Chemical | 29019 | KDU691 | 5mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 29019 | KDU691 | 10mg | $336 | 2024-03-01 | Buy |
| Cayman Chemical | 29019 | KDU691 | 25mg | $699 | 2024-03-01 | Buy |
| ChemScene | CS-0012775 | KDU691 99.56% | 5mg | $145 | 2021-12-16 | Buy |
| ChemScene | CS-0012775 | KDU691 99.56% | 10mg | $250 | 2021-12-16 | Buy |
Properties
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.24(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);23.82(Max Conc. mM) form :A crystalline solid
pka :14.59±0.46(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.24(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);23.82(Max Conc. mM) form :A crystalline solid
pka :14.59±0.46(Predicted)
Safety Information
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Description
KDU691 is an antimalarial compound. It inhibits recombinant P. vivax phosphatidylinositol 4-kinase (PI4K) with an IC50 value of 1.5 nM. KDU691 is selective for P. vivax PI4K over recombinant human PI4KβIII and PI3Kα, -β, -γ, and -δ (IC50s = 7.9, 8.8, 2.4, 8, and 3.4 μM, respectively), as well as VPS34 (IC50 = >9.7 μM) and 36 additional kinases in a panel of lipid and protein kinases (IC50s = >10 μM). It is active against P. falciparum and P. yoelii schizonts (IC50s = 0.06 and 0.04 μM, respectively), as well as P. cynomolgi schizonts and hypnozoites (IC50s = 0.11 and 0.2 μM, respectively). KDU691 completely prevents, but does not eradicate established, P. cynomolgi infection in rhesus monkeys when administered at a dose of 20 mg/kg.Suppliers and manufacturers
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