KDU691
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- $15 - $2492
- Product name: KDU691
- CAS: 1513879-19-0
- MF: C22H18ClN5O2
- MW: 419.86
- EINECS:
- MDL Number:
- Synonyms:KDU691;KDU691;KDU-691;KDU 691;1513879-19-0;KDU691 >=98% (HPLC);Imidazo[1,2-a]pyrazine-6-carboxamide, N-(4-chlorophenyl)-N-methyl-3-[4-[(methylamino)carbonyl]phenyl]-;PI4 kinases,blood,Inhibitor,liver,Phosphatidylinositol 4 kinases,ring-stage,falciparum,Parasite,plasmodium,schizonts,gametocytes,KDU 691,PI4K,KDU-691,inhibit,KDU691,stage;KDU691, 10 mM in DMSO;N-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide
47 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 2.5mg
- 2mg
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5 mg
- 25 mg
- Manufactureraablocks
- Product numberAA01EO6D
- Product descriptionN-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98%
- Packaging2mg
- Price$15
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO6D
- Product descriptionN-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98%
- Packaging5mg
- Price$32
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO6D
- Product descriptionN-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98%
- Packaging10mg
- Price$56
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO6D
- Product descriptionN-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98%
- Packaging25mg
- Price$95
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO6D
- Product descriptionN-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98%
- Packaging50mg
- Price$153
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EO6D
- Product descriptionN-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98%
- Packaging100mg
- Price$243
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228493
- Product descriptionKDU691 97.00%
- Packaging100MG
- Price$335
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228493
- Product descriptionKDU691 97.00%
- Packaging25MG
- Price$125
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3122EB
- Product descriptionCID90157166
- Packaging25mg
- Price$876
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging250mg
- Price$995
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging100mg
- Price$666
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging25mg
- Price$394
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging50mg
- Price$512
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging1g
- Price$2492
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging10mg
- Price$207
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA950283
- Product descriptionKdu691 98+%
- Packaging5mg
- Price$117
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EO6D | N-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98% | 2mg | $15 | 2026-05-30 | Buy |
| aablocks | AA01EO6D | N-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98% | 5mg | $32 | 2026-05-30 | Buy |
| aablocks | AA01EO6D | N-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98% | 10mg | $56 | 2026-05-30 | Buy |
| aablocks | AA01EO6D | N-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98% | 25mg | $95 | 2026-05-30 | Buy |
| aablocks | AA01EO6D | N-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98% | 50mg | $153 | 2026-05-30 | Buy |
| aablocks | AA01EO6D | N-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide ≥98% | 100mg | $243 | 2026-05-30 | Buy |
| ACHEMBLOCK | Y228493 | KDU691 97.00% | 100MG | $335 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228493 | KDU691 97.00% | 25MG | $125 | 2026-05-27 | Buy |
| AK Scientific | 3122EB | CID90157166 | 25mg | $876 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 250mg | $995 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 100mg | $666 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 25mg | $394 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 50mg | $512 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 1g | $2492 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 10mg | $207 | 2021-12-16 | Buy |
| Ambeed | A950283 | Kdu691 98+% | 5mg | $117 | 2021-12-16 | Buy |
Properties
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.24(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);23.82(Max Conc. mM) form :A crystalline solid
pka :14.59±0.46(Predicted)
color :White to off-white
InChI :1S/C22H18ClN5O2/c1-24-21(29)15-5-3-14(4-6-15)19-11-26-20-12-25-18(13-28(19)20)22(30)27(2)17-9-7-16(23)8-10-17/h3-13H,1-2H3,(H,24,29)
InChIKey :TYMFFISSODJRDV-UHFFFAOYSA-N
SMILES :O=C(N(C1=CC=C(Cl)C=C1)C)C(N=C2)=CN3C2=NC=C3C4=CC=C(C(NC)=O)C=C4
storage temp. :Store at -20°C
solubility :DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.24(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);23.82(Max Conc. mM) form :A crystalline solid
pka :14.59±0.46(Predicted)
color :White to off-white
InChI :1S/C22H18ClN5O2/c1-24-21(29)15-5-3-14(4-6-15)19-11-26-20-12-25-18(13-28(19)20)22(30)27(2)17-9-7-16(23)8-10-17/h3-13H,1-2H3,(H,24,29)
InChIKey :TYMFFISSODJRDV-UHFFFAOYSA-N
SMILES :O=C(N(C1=CC=C(Cl)C=C1)C)C(N=C2)=CN3C2=NC=C3C4=CC=C(C(NC)=O)C=C4
Safety Information
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Description
KDU691 is an antimalarial compound. It inhibits recombinant P. vivax phosphatidylinositol 4-kinase (PI4K) with an IC50 value of 1.5 nM. KDU691 is selective for P. vivax PI4K over recombinant human PI4KβIII and PI3Kα, -β, -γ, and -δ (IC50s = 7.9, 8.8, 2.4, 8, and 3.4 μM, respectively), as well as VPS34 (IC50 = >9.7 μM) and 36 additional kinases in a panel of lipid and protein kinases (IC50s = >10 μM). It is active against P. falciparum and P. yoelii schizonts (IC50s = 0.06 and 0.04 μM, respectively), as well as P. cynomolgi schizonts and hypnozoites (IC50s = 0.11 and 0.2 μM, respectively). KDU691 completely prevents, but does not eradicate established, P. cynomolgi infection in rhesus monkeys when administered at a dose of 20 mg/kg.Related product price
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