KN-93
|
- $50 - $3417
- Product name: KN-93
- CAS: 139298-40-1
- MF: C26H29ClN2O4S
- MW: 501.04
- EINECS:
- MDL Number:MFCD00236424
- Synonyms:2-[N-(2-HYDROXYETHYL)-N-(4-METHOXYBENZENESULFONYL)]AMINO-N-(4-CHLOROCINNAMYL)-N-METHYLBENZYLAMINE;METHOXYBENZENE-SULFONAMIDE;KN-93;KN-93, WATER-SOLUBLE;N-[2-[[[3-(4'-CHLOROPHENYL)-2-PROPENYL]METHYLAMINO]METHYL]PHENYL]-N-(2-HYDROXYETHYL)-4'-METHOXY-BENZENESULFONAMIDE PHOSPHATE;N-[2-[[[3-(4-CHLOROPHENYL)-2-PROPENYL]METHYLAMINO]METHYL]PHENYL]-N-(2-HYDROXYETHYL)-4-METHOXYBENZENESULPHONAMIDE;N-[2-N-4-CHLOROCINNAMYL-N-METHYLAMINOMETHYLPHENYL]-N-[2-HYDROXYETHYL]-4-METHOXYBENZENESULFONAMIDE;KN-93,98%
48 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 0.1mg
- 0.5mg
- 1mg
- 2mg
- 2.5MG
- 1
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product number3764AH
- Product descriptionMethoxybenzene-sulfonamide
- Packaging10mg
- Price$246
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3764AH
- Product descriptionMethoxybenzene-sulfonamide
- Packaging250mg
- Price$807
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3764AH
- Product descriptionMethoxybenzene-sulfonamide
- Packaging5g
- Price$3417
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170870
- Product descriptionKN-93 98+%
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170870
- Product descriptionKN-93 98+%
- Packaging5mg
- Price$101
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170870
- Product descriptionKN-93 98+%
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170870
- Product descriptionKN-93 98+%
- Packaging25mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170870
- Product descriptionKN-93 98+%
- Packaging50mg
- Price$246
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170870
- Product descriptionKN-93 98+%
- Packaging250mg
- Price$554
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170870
- Product descriptionKN-93 98+%
- Packaging1g
- Price$688
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170870
- Product descriptionKN-93 98+%
- Packaging5g
- Price$2487
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000352
- Product descriptionKN-93 95.00%
- Packaging1MG
- Price$436
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000352
- Product descriptionKN-93 95.00%
- Packaging2.5MG
- Price$704
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000352
- Product descriptionKN-93 95.00%
- Packaging25MG
- Price$1871.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3532
- Product descriptionKN-93
- Packaging25mg
- Price$318
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS462182
- Product descriptionKN-93 ≥98%
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3764AH | Methoxybenzene-sulfonamide | 10mg | $246 | 2021-12-16 | Buy |
| AK Scientific | 3764AH | Methoxybenzene-sulfonamide | 250mg | $807 | 2021-12-16 | Buy |
| AK Scientific | 3764AH | Methoxybenzene-sulfonamide | 5g | $3417 | 2021-12-16 | Buy |
| Ambeed | A170870 | KN-93 98+% | 1mg | $50 | 2021-12-16 | Buy |
| Ambeed | A170870 | KN-93 98+% | 5mg | $101 | 2021-12-16 | Buy |
| Ambeed | A170870 | KN-93 98+% | 10mg | $138 | 2021-12-16 | Buy |
| Ambeed | A170870 | KN-93 98+% | 25mg | $189 | 2021-12-16 | Buy |
| Ambeed | A170870 | KN-93 98+% | 50mg | $246 | 2021-12-16 | Buy |
| Ambeed | A170870 | KN-93 98+% | 250mg | $554 | 2021-12-16 | Buy |
| Ambeed | A170870 | KN-93 98+% | 1g | $688 | 2021-12-16 | Buy |
| Ambeed | A170870 | KN-93 98+% | 5g | $2487 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000352 | KN-93 95.00% | 1MG | $436 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000352 | KN-93 95.00% | 2.5MG | $704 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000352 | KN-93 95.00% | 25MG | $1871.1 | 2021-12-16 | Buy |
| ApexBio Technology | A3532 | KN-93 | 25mg | $318 | 2021-12-16 | Buy |
| Arctom | AS462182 | KN-93 ≥98% | 1mg | $50 | 2021-12-16 | Buy |
Properties
Density :1.288
storage temp. :2-8°C
solubility :DMSO: 1 mg/mL
form :Off-white solid
color :white
biological source :synthetic (organic)
Water Solubility :water: 5mg/mL
InChIKey :LLLQTDSSHZREGW-AATRIKPKSA-N
SMILES :OP(O)(O)=O.COc1ccc(cc1)S(=O)(=O)N(CCO)c2ccccc2CN(C)C\C=C\c3ccc(Cl)cc3
CAS DataBase Reference :139298-40-1(CAS DataBase Reference)
storage temp. :2-8°C
solubility :DMSO: 1 mg/mL
form :Off-white solid
color :white
biological source :synthetic (organic)
Water Solubility :water: 5mg/mL
InChIKey :LLLQTDSSHZREGW-AATRIKPKSA-N
SMILES :OP(O)(O)=O.COc1ccc(cc1)S(=O)(=O)N(CCO)c2ccccc2CN(C)C\C=C\c3ccc(Cl)cc3
CAS DataBase Reference :139298-40-1(CAS DataBase Reference)
Safety Information
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Description
KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. It inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). More recently, KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cells.More related product prices
N-Methyldiethanolamine N-METHYLBENZAMIDE 2-Methylaminoethanol N-Methylaniline N-Methyl pyrrole KN-93Related product price
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$20-1183.57 - N-METHYLBENZAMIDE
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$10-1166.55
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