L-165,041
|
- $48 - $2551
- Product name: L-165,041
- CAS: 79558-09-1
- MF: C22H26O7
- MW: 402.44
- EINECS:
- MDL Number:MFCD04974501
- Synonyms:L-165041, >=98%;2-[4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]-;2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid;Acetic acid, 2-[4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]-;L 1q5041;L-165,041;4-[3-(4-ACETYL-3-HYDROXY-2-PROPYLPHENOXY)PROPOXY]PHENOXYACETIC ACID;4-[3-(2-PROPYL-3-HYDROXY-4-ACETYL)PHENOXY]PROPYLOXYPHENOXY-ACETIC ACID
65 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 2mg
- 10mM(in 1mL DMSO)
- 10mM*1mLinDMSO(Solution)
- 50
- 10
- 1mlx10mM(inDMSO)
- 250.00mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA008LU7
- Product descriptionL-165,041
- Packaging5mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008LU7
- Product descriptionL-165,041
- Packaging10mg
- Price$72
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008LU7
- Product descriptionL-165,041
- Packaging25mg
- Price$124
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008LU7
- Product descriptionL-165,041
- Packaging50mg
- Price$198
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008LU7
- Product descriptionL-165,041
- Packaging100mg
- Price$304
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32757
- Product description2-(4-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid 98%
- Packaging1G
- Price$1200
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32757
- Product description2-(4-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid 98%
- Packaging100MG
- Price$240
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX6845
- Product description2-(4-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-propoxy)phenoxy)aceticacid
- Packaging250mg
- Price$2551
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA101739
- Product descriptionL-165041 97%
- Packaging50mg
- Price$335
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA101739
- Product descriptionL-165041 97%
- Packaging25mg
- Price$206
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA101739
- Product descriptionL-165041 97%
- Packaging100mg
- Price$534
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA101739
- Product descriptionL-165041 97%
- Packaging10mg
- Price$110
- Updated2026-06-05
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008434
- Product descriptionL-165,041 95.00%
- Packaging5MG
- Price$199.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008434
- Product descriptionL-165,041 95.00%
- Packaging10MG
- Price$702.19
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008434
- Product descriptionL-165,041 95.00%
- Packaging50MG
- Price$1199.42
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3536
- Product descriptionL-165041
- Packaging10mM(in1mLDMSO)
- Price$65
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008LU7 | L-165,041 | 5mg | $52 | 2026-05-28 | Buy |
| aablocks | AA008LU7 | L-165,041 | 10mg | $72 | 2026-05-28 | Buy |
| aablocks | AA008LU7 | L-165,041 | 25mg | $124 | 2026-05-28 | Buy |
| aablocks | AA008LU7 | L-165,041 | 50mg | $198 | 2026-05-28 | Buy |
| aablocks | AA008LU7 | L-165,041 | 100mg | $304 | 2026-05-28 | Buy |
| ACHEMBLOCK | O32757 | 2-(4-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid 98% | 1G | $1200 | 2026-05-27 | Buy |
| ACHEMBLOCK | O32757 | 2-(4-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid 98% | 100MG | $240 | 2026-05-27 | Buy |
| AK Scientific | X6845 | 2-(4-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-propoxy)phenoxy)aceticacid | 250mg | $2551 | 2021-12-16 | Buy |
| Ambeed | A101739 | L-165041 97% | 50mg | $335 | 2026-06-05 | Buy |
| Ambeed | A101739 | L-165041 97% | 25mg | $206 | 2026-06-05 | Buy |
| Ambeed | A101739 | L-165041 97% | 100mg | $534 | 2026-06-05 | Buy |
| Ambeed | A101739 | L-165041 97% | 10mg | $110 | 2026-06-05 | Buy |
| American Custom Chemicals Corporation | API0008434 | L-165,041 95.00% | 5MG | $199.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008434 | L-165,041 95.00% | 10MG | $702.19 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008434 | L-165,041 95.00% | 50MG | $1199.42 | 2021-12-16 | Buy |
| ApexBio Technology | A3536 | L-165041 | 10mM(in1mLDMSO) | $65 | 2026-05-06 | Buy |
Properties
Melting point :127-128 °C(lit.)
Boiling point :600.8±55.0 °C(Predicted)
Density :1.222±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10 mg/mL
form :solid
pka :3.23±0.10(Predicted)
color :off-white
Stability :Light Sensitive
InChI :1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25)
InChIKey :HBBVCKCCQCQCTJ-UHFFFAOYSA-N
SMILES :CCCc1c(O)c(ccc1OCCCOc2ccc(OCC(O)=O)cc2)C(C)=O
Boiling point :600.8±55.0 °C(Predicted)
Density :1.222±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10 mg/mL
form :solid
pka :3.23±0.10(Predicted)
color :off-white
Stability :Light Sensitive
InChI :1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25)
InChIKey :HBBVCKCCQCQCTJ-UHFFFAOYSA-N
SMILES :CCCc1c(O)c(ccc1OCCCOc2ccc(OCC(O)=O)cc2)C(C)=O
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
L-165041 is a cell permeable PPARβ (peroxisome proliferator-activated receptor β) agonist which induces adipocyte differentiation in NIH-PPARβ cells. In addition, this ligand reduces lipid accumulation in the liver and decreases total hepatic cholesterol and triglyceride content. Studies suggest that L-165041 affects mRNA expression by reducing the expression of PPARγ, apolipoprotein B, interleukin 1 β (IL-1β), and interleukin-6, while increasing the expression of PPARβ, lipoprotein lipase (LPL), and ATP-binding cassette transporter G1 (ABCG1). Furthermore, upon binding to PPARβ L-165041 suppresses vascular smooth muscle proliferation and migration by inhibiting the cell cycle, specifically blocking G1 to S phase progression and repressing the phosphorylation of retinoblastoma protein (Rb) in rats. Alternate studies suggest that L-165041 suppresses the cytokine-induced expression of VCAM-1 (vascular cell adhesion molecule-1) and increases UCP3 (uncoupling protein 3) gene expression in L6 myotubes. L-165041 is an activator of PPAR beta.Related product price
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