L-(-)-Ephedrine

$638
Product name: L-(-)-Ephedrine
CAS: 492-41-1
MF: C9H13NO
MW: 151.21
EINECS:207-755-7
MDL Number:MFCD00066044
Synonyms:Benzyl alcohol,alpha-(1-aminoethyl)-;Fenilpropanolamina;l-phenylpropanolamine ;Mydriatin;Norephedrine, (-)-;Propadrine;USAF cs-6;(-)-benzylalcoho

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250g

ManufacturerAHH
Product numberMT-20274
Product description(1R,2S)-(-)-Norephedrine 97%
Packaging250g
Price$638
Updated2026-05-26
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Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AHH	MT-20274	(1R,2S)-(-)-Norephedrine 97%	250g	$638	2026-05-26	Buy

Properties

Melting point :51-53 °C(lit.)
alpha :-41 º (c=7, 1M HCl)
Boiling point :273.23°C (rough estimate)
Density :1.0406 (rough estimate)
refractive index :1.5380 (estimate)
Flash point :>230 °F
storage temp. :2-8°C
form :A solid
pka :9.958(at 10℃)
optical activity :[α]20/D -41°, c =7 in 1 M HCl
Stability :Stable. Incompatible with strong oxidizing agents. May discolour on exposure to light.
InChI :1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m0/s1
InChIKey :DLNKOYKMWOXYQA-CBAPKCEASA-N
SMILES :C[C@H](N)[C@H](O)c1ccccc1
CAS DataBase Reference :492-41-1(CAS DataBase Reference)
NIST Chemistry Reference :Phenylpropanolamine(492-41-1)
EPA Substance Registry System :Benzenemethanol, .alpha.-[(1S)-1-aminoethyl]-, (.alpha.R)- (492-41-1)

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

This alkaloid was first isolated by Kanao from the Chinese drug 'Ma-Huang' (Ephedra sinica Stapf.) and later by Wolfes from E. helvetica C. A. Meyer and E. distachya Linn. It forms a crystalline mass and has [α] ²⁰ _D - 14.56° (EtOH). Several crystalline salts and derivatives are known: the hydrochloride has m.p. 171-2°C; [α] ²⁰ _D- 33.27° (H20); the sulphate dihydrate, m.p. 285-6°C (dry, dec.); [α] ²⁸ _D- 31.99° (H20); the aurichloride, m.p. 188°C; platinichloride, m.p. 221°C (dec.); (-)-hydrogen tartrate, m.p. about 160° after sintering at 130°C; oxalate, m.p. 245°C (dec.) and the p-nitrobenzoyl derivative, m.p. 175-6°C; [α] ²⁸ _D- 49.58° (CHCI3).
The (+)-form has m.p. 52°C; [α] ²⁷ _D + 14.76° (EtOH), yielding a hydro_x0002_chloride, m.p. 171-2°C; [α] ²⁷ _D + 33.4° (EtOH); sulphate dihydrate, m.p. 285- 6°C (dry, dec.); [α] ²⁷ _D+ 31.51 0 C (H20); aurichloride, m.p. 188°C (dec.) and platinichloride, m.p. 221.5°C (dec.). The (±)-form crystallizes as colourless plates from Et20, m.p. 104-5°C and also furnishes a series of crystalline salts and derivatives.

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