LACTACYSTIN
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- $43 - $2200
- Product name: LACTACYSTIN
- CAS: 133343-34-7
- MF: C15H24N2O7S
- MW: 376.43
- EINECS:200-258-5
- MDL Number:MFCD01076525
- Synonyms:(2R,3S,4R)-3-HYDROXY-2-[(1S)-1-HYDROXY-2-METHYLPROPYL]-4-METHYL-5-OXO-2-PYRROLIDINECARBOXY-N-ACETYL-L-CYSTEINE THIOESTER;3S-HYDROXY-2R-(1-HYDROXY-2-METHYLPROPYL)-4R-METHYL-5-OXO-2-PYRROLIDINECARBOXYLATE-N-ACETYL-L-CYSTEINE;(+)-LACTACYSTIN;LACTACYSTIN;LACTACYSTIN (NATIVE);LACTACYSTIN, STREPTOMYCES SP;LACTACYSTIN, SYNTHETIC;N-ACETYL-S-[(2R,3S,4R)-3-HYDROXY-2-[(1S)-1-HYDROXY-2-METHYLPROPYL]-4-METHYL-5-OXO-2-PYRROLIDINECARBONYL]-L-CYSTEINE
25 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 50μg
- 100ug
- 100μg
- 200ug
- 0.2mg
- 0.25mg
- 500ug
- 500μg
- 1mg
- 1.25mg
- 5mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0104-C100
- Product descriptionLactacystin ≥98%(HPLC)
- Packaging100μg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0315
- Product descriptionLactacystin
- Packaging1mg
- Price$818
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2583
- Product descriptionLactacystin (Synthetic)
- Packaging1mg
- Price$983
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2583
- Product descriptionLactacystin (Synthetic)
- Packaging100ug
- Price$133
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2583
- Product descriptionLactacystin (Synthetic)
- Packaging500ug
- Price$563
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2583
- Product descriptionLactacystin(Synthetic)
- Packaging1mg
- Price$737
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN00121
- Product descriptionLactacystin ≥98%
- Packaging5mg
- Price$463
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545880
- Product descriptionLactacystin >98%
- Packaging200ug
- Price$292.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545880
- Product descriptionLactacystin >98%
- Packaging1mg
- Price$902.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number70980
- Product descriptionLactacystin ≥98%
- Packaging500μg
- Price$237
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number70980
- Product descriptionLactacystin ≥98%
- Packaging100μg
- Price$75
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70980
- Product descriptionLactacystin ≥98%
- Packaging50μg
- Price$43
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number70980
- Product descriptionLactacystin ≥98%
- Packaging50μg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70980
- Product descriptionLactacystin ≥98%
- Packaging100μg
- Price$69
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number70980
- Product descriptionLactacystin ≥98%
- Packaging500μg
- Price$308
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70980
- Product descriptionLactacystin ≥98%
- Packaging1mg
- Price$387
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0104-C100 | Lactacystin ≥98%(HPLC) | 100μg | $70 | 2021-12-16 | Buy |
| AK Scientific | V0315 | Lactacystin | 1mg | $818 | 2021-12-16 | Buy |
| ApexBio Technology | A2583 | Lactacystin (Synthetic) | 1mg | $983 | 2026-05-06 | Buy |
| ApexBio Technology | A2583 | Lactacystin (Synthetic) | 100ug | $133 | 2026-05-06 | Buy |
| ApexBio Technology | A2583 | Lactacystin (Synthetic) | 500ug | $563 | 2026-05-06 | Buy |
| ApexBio Technology | A2583 | Lactacystin(Synthetic) | 1mg | $737 | 2021-12-16 | Buy |
| Arctom | CFN00121 | Lactacystin ≥98% | 5mg | $463 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545880 | Lactacystin >98% | 200ug | $292.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545880 | Lactacystin >98% | 1mg | $902.7 | 2021-12-16 | Buy |
| Cayman Chemical | 70980 | Lactacystin ≥98% | 500μg | $237 | 2026-04-30 | Buy |
| Cayman Chemical | 70980 | Lactacystin ≥98% | 100μg | $75 | 2024-03-01 | Buy |
| Cayman Chemical | 70980 | Lactacystin ≥98% | 50μg | $43 | 2026-04-30 | Buy |
| Cayman Chemical | 70980 | Lactacystin ≥98% | 50μg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 70980 | Lactacystin ≥98% | 100μg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 70980 | Lactacystin ≥98% | 500μg | $308 | 2024-03-01 | Buy |
| Cayman Chemical | 70980 | Lactacystin ≥98% | 1mg | $387 | 2026-04-30 | Buy |
Properties
Melting point :233-235°C dec.
Boiling point :714.9±60.0 °C(Predicted)
Density :1.367±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 20 mg/ml), in Water (up to 10 mg/ml), or in Ethanol (up to 1 mg/ml).
form :powder
pka :3.11±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble to 10 mM in water
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used with one working day. Aqueous solutions should not be stored.
InChIKey :DAQAKHDKYAWHCG-RWTHQLGUSA-N
SMILES :CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(C)=O)C(O)=O
Boiling point :714.9±60.0 °C(Predicted)
Density :1.367±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 20 mg/ml), in Water (up to 10 mg/ml), or in Ethanol (up to 1 mg/ml).
form :powder
pka :3.11±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble to 10 mM in water
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used with one working day. Aqueous solutions should not be stored.
InChIKey :DAQAKHDKYAWHCG-RWTHQLGUSA-N
SMILES :CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(C)=O)C(O)=O
Safety Information
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Description
Lactacystin is a microbial metabolite isolated from Streptomyces that is now widely used as a selective inhibitor of the 20S proteasome. Lactacystin was first characterized by its ability to induce differentiation and inhibit cell cycle progression in several tumor cell lines. At concentrations from 2 to 10 μM, lactacystin induces the outgrowth of neurites in the neuroblastoma cell line Neuro2a. Lactacystin irreversibly alkylates subunit X of the 20S proteasome. The concomitant inhibition of proteasome peptidase activity results in the accumulation of a variety of ubiquitinated proteins which would normally undergo rapid degradation. Thus, the effects of lactacystin are pleiotropic and depend substantially on the expression pattern of signalling proteins within the treated cell.Related product price
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Suppliers and manufacturers
Dideu Industries Group Limited
Wuhan Topule Biopharmaceutical Co., Ltd
Shanghai Acmec Biochemical Technology Co., Ltd.
SHANGHAI KEAN TECHNOLOGY CO., LTD.
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chemsky（shanghai）International Co.,Ltd.
Jinan Trio PharmaTech Co., Ltd.
