LCZ696
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- $36 - $1587
- Product name: LCZ696
- CAS: 936623-90-4
- MF: C48H58N6O8
- MW: 847.03
- EINECS:-0
- MDL Number:MFCD29477717
- Synonyms:LCZ696 ENTRESTO TM;LCZ696 Entresto;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate;Cocrystal of Sacubitril and Valsartan;(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)hexanamido)-3-methylbutanoic acid;lcz696/Valsartan/sacubitril;Sacubitril-Valsartan complex;3-(1-Biphenyl-4-ylMethyl-3-ethoxycarbonyl-1-butylcarbaMoyl)propionate-3'-Methyl-2'-(pentanoyl(2'-(tetrazol-5-ylate)biphenyl-4'-ylMethyl)aMino)butyrate
55 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- Activate Scientific
- AK Scientific
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- TRC
Package
- 25mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 5mg
- 50mg
- 10mM*1mLinDMSO
- 10mg
- 10mM*1mLinDMSO(Solution)
- 10mM(1mLinDMSO)
- 10mM(in 1mL DMSO)
- 100mg
- 250mg
- 500mg
- 1g
- 5g
- 50g
- 100g
- 0.5kg
- 10mM(in1mLDMSO)
- 0.25kg
- 1kg
- Manufactureraablocks
- Product numberAA00GTSZ
- Product descriptionL-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) ≥98%(1:1ratioofValsartanandAHU377)
- Packaging10mg
- Price$41
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTSZ
- Product descriptionL-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) ≥99%
- Packaging100mg
- Price$60
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTSZ
- Product descriptionL-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) 95%
- Packaging250mg
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTSZ
- Product descriptionL-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) 95%
- Packaging1g
- Price$209
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTSZ
- Product descriptionL-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) 95%
- Packaging5g
- Price$468
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16034
- Product descriptionLCZ696 99%
- Packaging5G
- Price$356
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16034
- Product descriptionLCZ696 99%
- Packaging100MG
- Price$36
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16034
- Product descriptionLCZ696 99%
- Packaging1G
- Price$81
- Updated2026-05-27
- Buy
- ManufacturerActivate Scientific
- Product numberAS112365
- Product descriptionLCZ 696 98%
- Packaging1g
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9052AF
- Product descriptionLCZ696
- Packaging100mg
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9052AF
- Product descriptionLCZ696
- Packaging5g
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4815
- Product descriptionLCZ696
- Packaging100mg
- Price$690
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4815
- Product descriptionLCZ696
- Packaging5mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4815
- Product descriptionLCZ696
- Packaging10mg
- Price$94
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4815
- Product descriptionLCZ696
- Packaging10mM(in1mLDMSO)
- Price$99
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4815
- Product descriptionLCZ696
- Packaging25mg
- Price$300
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GTSZ | L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) ≥98%(1:1ratioofValsartanandAHU377) | 10mg | $41 | 2026-05-28 | Buy |
| aablocks | AA00GTSZ | L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) ≥99% | 100mg | $60 | 2026-05-28 | Buy |
| aablocks | AA00GTSZ | L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) 95% | 250mg | $79 | 2026-05-28 | Buy |
| aablocks | AA00GTSZ | L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) 95% | 1g | $209 | 2026-05-28 | Buy |
| aablocks | AA00GTSZ | L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5) 95% | 5g | $468 | 2026-05-28 | Buy |
| ACHEMBLOCK | R16034 | LCZ696 99% | 5G | $356 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16034 | LCZ696 99% | 100MG | $36 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16034 | LCZ696 99% | 1G | $81 | 2026-05-27 | Buy |
| Activate Scientific | AS112365 | LCZ 696 98% | 1g | $108 | 2021-12-16 | Buy |
| AK Scientific | 9052AF | LCZ696 | 100mg | $113 | 2021-12-16 | Buy |
| AK Scientific | 9052AF | LCZ696 | 5g | $490 | 2021-12-16 | Buy |
| ApexBio Technology | B4815 | LCZ696 | 100mg | $690 | 2021-12-16 | Buy |
| ApexBio Technology | B4815 | LCZ696 | 5mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | B4815 | LCZ696 | 10mg | $94 | 2026-05-06 | Buy |
| ApexBio Technology | B4815 | LCZ696 | 10mM(in1mLDMSO) | $99 | 2026-05-06 | Buy |
| ApexBio Technology | B4815 | LCZ696 | 25mg | $300 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :≥45.05 mg/mL in DMSO; ≥11.28 mg/mL in H2O; ≥28.5 mg/mL in EtOH
form :solid
color :White to light yellow
InChIKey :XTKIDERFOUYBDE-NOFROVMTNA-N
SMILES :C(C1C=CC(C2C=CC=CC=2C2=NN=NN2)=CC=1)N(C(=O)CCCC)[C@H](C(=O)O)C(C)C.C(C1C=CC(C2C=CC=CC=2)=CC=1)[C@@H](NC(=O)CCC(=O)O)C[C@@H](C)C(=O)OCC |&1:25,45,55,r|
solubility :≥45.05 mg/mL in DMSO; ≥11.28 mg/mL in H2O; ≥28.5 mg/mL in EtOH
form :solid
color :White to light yellow
InChIKey :XTKIDERFOUYBDE-NOFROVMTNA-N
SMILES :C(C1C=CC(C2C=CC=CC=2C2=NN=NN2)=CC=1)N(C(=O)CCCC)[C@H](C(=O)O)C(C)C.C(C1C=CC(C2C=CC=CC=2)=CC=1)[C@@H](NC(=O)CCC(=O)O)C[C@@H](C)C(=O)OCC |&1:25,45,55,r|
Safety Information
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| Signal word: | Warning | |||||||
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Description
LCZ696 is a dual angiotensin II receptor antagonist and neprilysin inhibitor that is a combination of the nonpeptide angiotensin II receptor antagonist valsartan and AHU377 , a prodrug of LBQ657 , which is an inhibitor of the zinc metallopeptidase neprilysin., LCZ696 (2-60 mg/kg) induces a dose-dependent decrease in mean arterial pressure in rats expressing human renin and angiotensinogen, a double-transgenic model for angiotensin II-dependent hypertension. Formulations containing LCZ696 are under clinical investigation for the treatment of mild to moderate hypertension and chronic heart failure.More related product prices
Valsartan (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid AHU-377 (heMicalciuM salt) (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate sacubitril AHU-377 (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acidRelated product price
Suppliers and manufacturers
Chongqing Chemieliva Pharmaceutical Co., Ltd.
Suzhou Chukai PharmaTech
Changzhou Yuanda Pharmaceutical Chemical Co., Ltd.
INTERCHEMIE NANJING PHARMATECH CO., LTD
Jiangsu Vcare PharmaTech Co., Ltd.
Shandong Sihuan Pharmaceutical Co., Ltd.
Shanghai Haoyuan Chemexpress Co., Ltd.
CHANGZHOU PHARMACEUTICAL FACTORY
Shanghai Boyle Chemical Co., Ltd.
Beijing HwrkChemical Technology Co., Ltd




