Leptomycin B
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- $36 - $1190
- Product name: Leptomycin B
- CAS: 87081-35-4
- MF: C33H48O6
- MW: 540.73
- EINECS:617-954-4
- MDL Number:MFCD06795848
- Synonyms:(2E,10Z,12E,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxo-nonadeca-2,10,12,16,18-pentaenoic acid;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-;2,10,12,16,18-Nonadecapentanoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-;(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoicacid;LeptoMycin B( CI 940, LMB);antibioticcl1957a ;CI-940, Elactocin, PD 114720, ATS 1287B, Mantuamycin, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic acid;Elactocin, ATS 1287B, CI 940, CL 1957A, PD 114720, MantuaMycin
16 prices
Selected condition：
Brand
- Apolloscientific
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 0.5μg
- 2x0.5μg
- 5x0.5μg
- 10x0.5μg
- 5μg
- 5ug
- 10μg
- 25μg
- 100μg
- 500μg
- 500ug
- 1mg
- 25g
- ManufacturerApolloscientific
- Product numberBIL2101
- Product descriptionLeptomycinB
- Packaging100μg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIL2101
- Product descriptionLeptomycinB
- Packaging500μg
- Price$508
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIL2101
- Product descriptionLeptomycinB
- Packaging1mg
- Price$907
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10004976
- Product descriptionLeptomycin B ≥98%
- Packaging5μg
- Price$36
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10004976
- Product descriptionLeptomycin B ≥98%
- Packaging10μg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10004976
- Product descriptionLeptomycin B ≥98%
- Packaging25μg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0012947
- Product descriptionLeptomycinB 99.71%
- Packaging5ug
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number74786
- Product descriptionLeptomycinB >99%
- Packaging500ug
- Price$1190
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number431050
- Product descriptionInSolution Leptomycin B, Streptomyces sp. - CAS 87081-35-4 - Calbiochem An antifungal antibiotic that acts as an inhibitor of nuclear export because of its ability to interact with and impair the function of the nuclear export factor CRM1.
- Packaging5μg
- Price$313.57
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number431050
- Product descriptionInSolution? Leptomycin B,
- Packaging5ug
- Price$327
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging5μg
- Price$410
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging10x0.5μg
- Price$377
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging5x0.5μg
- Price$241
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging2x0.5μg
- Price$110
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging0.5μg
- Price$59.3
- Updated2025-07-31
- Buy
- ManufacturerTRC
- Product numberL329650
- Product descriptionLeptomycinB
- Packaging25g
- Price$90
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Apolloscientific | BIL2101 | LeptomycinB | 100μg | $138 | 2021-12-16 | Buy |
| Apolloscientific | BIL2101 | LeptomycinB | 500μg | $508 | 2021-12-16 | Buy |
| Apolloscientific | BIL2101 | LeptomycinB | 1mg | $907 | 2021-12-16 | Buy |
| Cayman Chemical | 10004976 | Leptomycin B ≥98% | 5μg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 10004976 | Leptomycin B ≥98% | 10μg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 10004976 | Leptomycin B ≥98% | 25μg | $120 | 2024-03-01 | Buy |
| ChemScene | CS-0012947 | LeptomycinB 99.71% | 5ug | $300 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 74786 | LeptomycinB >99% | 500ug | $1190 | 2021-12-16 | Buy |
| Sigma-Aldrich | 431050 | InSolution Leptomycin B, Streptomyces sp. - CAS 87081-35-4 - Calbiochem An antifungal antibiotic that acts as an inhibitor of nuclear export because of its ability to interact with and impair the function of the nuclear export factor CRM1. | 5μg | $313.57 | 2021-12-16 | Buy |
| Sigma-Aldrich | 431050 | InSolution? Leptomycin B, | 5ug | $327 | 2021-12-16 | Buy |
| Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 5μg | $410 | 2025-07-31 | Buy |
| Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 10x0.5μg | $377 | 2025-07-31 | Buy |
| Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 5x0.5μg | $241 | 2025-07-31 | Buy |
| Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 2x0.5μg | $110 | 2025-07-31 | Buy |
| Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 0.5μg | $59.3 | 2025-07-31 | Buy |
| TRC | L329650 | LeptomycinB | 25g | $90 | 2021-12-16 | Buy |
Properties
Melting point :41-44°, with prior softening (Hokanson)
alpha :D -24.5° (c = 0.70 in MeOH); D23 -157 ° (c = 0.7% in chloroform)
Boiling point :725.8±60.0 °C(Predicted)
Density :1.072±0.06 g/cm3(Predicted)
Flash point :11°(52°F)
storage temp. :−20°C
solubility :Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.
form :Liquid
pka :5.10±0.33(Predicted)
color :White to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions or dilutions in DMSO are not stable. Solutions should be made fresh and used within one working day.
InChIKey :YACHGFWEQXFSBS-XYERBDPFSA-N
SMILES :C(O)(=O)/C=C(\C)/C[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@H](C)/C=C(\C)/C=C/C[C@@H](C)/C=C(/CC)\C=C\[C@@H]1OC(=O)C=C[C@@H]1C
alpha :D -24.5° (c = 0.70 in MeOH); D23 -157 ° (c = 0.7% in chloroform)
Boiling point :725.8±60.0 °C(Predicted)
Density :1.072±0.06 g/cm3(Predicted)
Flash point :11°(52°F)
storage temp. :−20°C
solubility :Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.
form :Liquid
pka :5.10±0.33(Predicted)
color :White to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions or dilutions in DMSO are not stable. Solutions should be made fresh and used within one working day.
InChIKey :YACHGFWEQXFSBS-XYERBDPFSA-N
SMILES :C(O)(=O)/C=C(\C)/C[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@H](C)/C=C(\C)/C=C/C[C@@H](C)/C=C(/CC)\C=C\[C@@H]1OC(=O)C=C[C@@H]1C
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleusRelated product price
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