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ChemicalBook >> CAS DataBase List >> Lovastatin

Lovastatin

Lovastatin price.
  • $20 - $1208.7
  • Product name: Lovastatin
  • CAS: 75330-75-5
  • MF: C24H36O5
  • MW: 404.54
  • EINECS:616-212-7
  • MDL Number:MFCD00072164
  • Synonyms:SiMvastatin EP IMpurity E;8-[2-(4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-nap;6alpha-Methylcompactin Mevinolin Monacolin K;)ethyl]-1-naphthalenylester ;[1s-[1alpha(r*),3alpha,7beta,8beta(2s*,4s*),8abeta]]-2-methylbutanoicacid1,2, ;1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobuty ;2-methyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-butanoicaci ;3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl
47 prices
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Aronis compounds
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • y0001136
  • l0790000
  • 1mg
  • 5mg
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  • 100mg
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  • 10
  • 10mM(in 1mL DMSO)
  • 250mg
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  • 1g
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  • 25g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0051-M005
  • Product descriptionLovastatin ≥98%(HPLC)
  • Packaging5mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1658
  • Product descriptionLovalip 98%
  • Packaging5g
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10136
  • Product descriptionLovastatin
  • Packaging100mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH52792
  • Product descriptionLovastatin, 97%
  • Packaging5g
  • Price$67.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH52792
  • Product descriptionLovastatin, 97%
  • Packaging25g
  • Price$317
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0294639
  • Product descriptionSIMVASTATIN EP IMPURITY E 95.00%
  • Packaging5MG
  • Price$500.63
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4365
  • Product descriptionLovastatin
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99961
  • Product descriptionLovastatin ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numberBBC/353
  • Product description8-[2-(4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl2-methylbutanoate
  • Packaging1g
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1646
  • Product descriptionLovastatin
  • Packaging25mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1646
  • Product descriptionLovastatin
  • Packaging100mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1646
  • Product descriptionLovastatin
  • Packaging1g
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1646
  • Product descriptionLovastatin
  • Packaging10g
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594529
  • Product descriptionLovastatin
  • Packaging20mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180780
  • Product descriptionLovastatin (MK-803) >98%
  • Packaging100mg
  • Price$414.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180780
  • Product descriptionLovastatin (MK-803) >98%
  • Packaging250mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0051-M005 Lovastatin ≥98%(HPLC) 5mg $20 2021-12-16 Buy
AHH API-1658 Lovalip 98% 5g $460 2021-12-16 Buy
AK Scientific J10136 Lovastatin 100mg $95 2021-12-16 Buy
Alfa Aesar H52792 Lovastatin, 97% 5g $67.65 2024-03-01 Buy
Alfa Aesar H52792 Lovastatin, 97% 25g $317 2024-03-01 Buy
American Custom Chemicals Corporation CHM0294639 SIMVASTATIN EP IMPURITY E 95.00% 5MG $500.63 2021-12-16 Buy
ApexBio Technology A4365 Lovastatin 10mM(in 1mL DMSO) $55 2021-12-16 Buy
Arctom CFN99961 Lovastatin ≥98% 20mg $30 2021-12-16 Buy
Aronis compounds BBC/353 8-[2-(4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl2-methylbutanoate 1g $133 2021-12-16 Buy
AvaChem 1646 Lovastatin 25mg $29 2021-12-16 Buy
AvaChem 1646 Lovastatin 100mg $39 2021-12-16 Buy
AvaChem 1646 Lovastatin 1g $59 2021-12-16 Buy
AvaChem 1646 Lovastatin 10g $179 2021-12-16 Buy
Biorbyt Ltd orb594529 Lovastatin 20mg $187 2021-12-16 Buy
Biorbyt Ltd orb180780 Lovastatin (MK-803) >98% 100mg $414.8 2021-12-16 Buy
Biorbyt Ltd orb180780 Lovastatin (MK-803) >98% 250mg $615.4 2021-12-16 Buy

Properties

Melting point :175°C
alpha :D25 +323° (c = 0.5 g in 100 ml acetonitrile)
Boiling point :559.2±50.0 °C(Predicted)
Density :1.12±0.1 g/cm3(Predicted)
vapor pressure :0Pa at 25℃
refractive index :320 ° (C=0.5, CH3CN)
storage temp. :-20°C
solubility :ethanol: soluble9.80-10.20mg/mL, clear, colorless to faintly yellow
form :White to off-white powder
pka :13.49±0.40(Predicted)
color :White
Water Solubility :0.0004 mg/mL at 25 ºC
Merck :14,5586
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
LogP :4.260
CAS DataBase Reference :75330-75-5(CAS DataBase Reference)
EPA Substance Registry System :Lovastatin (75330-75-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Lovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.

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