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ChemicalBook >> CAS DataBase List >> Lys05

Lys05

Lys05 price.
  • $57 - $499
  • Product name: Lys05
  • CAS: 1391426-24-6
  • MF: C23H24Cl3N5
  • MW: 476.83
  • EINECS:
  • MDL Number:
  • Synonyms:Lys01 (trihydrochloride);lys05(3hcl);Lys05 trihydrochloride;Lys01 3HCl;COMPONENT: 1391426-22-4;Lys05(Component: 1391426-22-4);Lys05 (Lys01 trihydrochloride);Lys05 >=98% (HPLC)
8 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • DC Chemicals
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number1698DU
  • Product descriptionLys01trihydrochloride
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1698DU
  • Product descriptionLys01trihydrochloride
  • Packaging10mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1698DU
  • Product descriptionLys01trihydrochloride
  • Packaging50mg
  • Price$499
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27334
  • Product descriptionLys05 (hydrochloride)
  • Packaging5mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27334
  • Product descriptionLys05 (hydrochloride)
  • Packaging10mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27334
  • Product descriptionLys05 (hydrochloride)
  • Packaging25mg
  • Price$208
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27334
  • Product descriptionLys05 (hydrochloride)
  • Packaging50mg
  • Price$360
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10358
  • Product descriptionLys01trihydrochloride >98%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1698DU Lys01trihydrochloride 5mg $160 2021-12-16 Buy
AK Scientific 1698DU Lys01trihydrochloride 10mg $209 2021-12-16 Buy
AK Scientific 1698DU Lys01trihydrochloride 50mg $499 2021-12-16 Buy
Cayman Chemical 27334 Lys05 (hydrochloride) 5mg $57 2024-03-01 Buy
Cayman Chemical 27334 Lys05 (hydrochloride) 10mg $100 2024-03-01 Buy
Cayman Chemical 27334 Lys05 (hydrochloride) 25mg $208 2024-03-01 Buy
Cayman Chemical 27334 Lys05 (hydrochloride) 50mg $360 2024-03-01 Buy
DC Chemicals DC10358 Lys01trihydrochloride >98% 100mg $450 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO:12.0(Max Conc. mg/mL);21.83(Max Conc. mM)
Water:4.7(Max Conc. mg/mL);8.55(Max Conc. mM) form :A crystalline solid
InChIKey :KXCXCUSYQCJULU-UHFFFAOYSA-N
SMILES :N(C1=CC=NC2C=C(Cl)C=CC1=2)CCN(C)CCNC1=CC=NC2C=C(Cl)C=CC1=2.Cl

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Lys05, or Lys01 trihydrochloride, is a potent, water soluble lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ. Lys05 produced more potent antitumor activity as a single agent both in vitro and in vivo in multiple human cancer cell lines and xenograft models compared with HCQ. Lys05 is therefore a new lysosomal autophagy inhibitor that has potential to be developed further into a drug for cancer and other medical applications.