METHYSERGIDE MALEATE
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- $32 - $1385
- Product name: METHYSERGIDE MALEATE
- CAS: 129-49-7
- MF: C25H31N3O6
- MW: 469.54
- EINECS:204-950-9
- MDL Number:MFCD00083185
- Synonyms:1-(hydroxymethyl)propylamideof1-methyl-(+)-lysergicacidhydrogenmaleate ;deseril-retard ;ergoline-8-beta-carboxamide,9,10-didehydro-n-(1-(hydroxymethyl)propyl)-1,6-dim ;maleate(1:1)(salt) ;Methysergide Maleate, USP;Methysergide Maleate (350 mg);methysergidebimaleate ;methysergidedimaleate
21 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10
- 1mg
- 2mg
- 10MG
- 50
- 25mg
- 50MG
- 350mg
- ManufacturerAK Scientific
- Product numberG831
- Product descriptionMethysergide maleate
- Packaging25mg
- Price$522
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002261
- Product descriptionDESERIL 95.00%
- Packaging10MG
- Price$726.44
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002261
- Product descriptionDESERIL 95.00%
- Packaging50MG
- Price$1352.22
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5046
- Product descriptionMethysergide maleate
- Packaging10mg
- Price$329
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5046
- Product descriptionMethysergide maleate
- Packaging50mg
- Price$1385
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27658
- Product descriptionMethysergide (maleate)
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27658
- Product descriptionMethysergide (maleate)
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27658
- Product descriptionMethysergide (maleate)
- Packaging10mg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27658
- Product descriptionMethysergide (maleate)
- Packaging25mg
- Price$381
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberM137
- Product descriptionMethysergide maleate salt solid
- Packaging2mg
- Price$91.2
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number5.06419
- Product descriptionMethysergide Maleate - CAS 129-49-7 - Calbiochem
- Packaging10mg
- Price$201
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberBP409
- Product descriptionMethysergide maleate British Pharmacopoeia (BP) Reference Standard
- Packaging50MG
- Price$210
- Updated2022-05-15
- Buy
- ManufacturerSigma-Aldrich
- Product number1440003
- Product descriptionMethysergide maleate United States Pharmacopeia (USP) Reference Standard
- Packaging350mg
- Price$289
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberM137
- Product descriptionMethysergide maleate salt solid
- Packaging10mg
- Price$308
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberM137
- Product descriptionMethysergide maleate salt solid
- Packaging50mg
- Price$1050
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1064
- Product descriptionMethysergide maleate ≥99%(HPLC)
- Packaging10
- Price$227
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | G831 | Methysergide maleate | 25mg | $522 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002261 | DESERIL 95.00% | 10MG | $726.44 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002261 | DESERIL 95.00% | 50MG | $1352.22 | 2021-12-16 | Buy |
| ApexBio Technology | B5046 | Methysergide maleate | 10mg | $329 | 2021-12-16 | Buy |
| ApexBio Technology | B5046 | Methysergide maleate | 50mg | $1385 | 2021-12-16 | Buy |
| Cayman Chemical | 27658 | Methysergide (maleate) | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 27658 | Methysergide (maleate) | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 27658 | Methysergide (maleate) | 10mg | $169 | 2024-03-01 | Buy |
| Cayman Chemical | 27658 | Methysergide (maleate) | 25mg | $381 | 2024-03-01 | Buy |
| Sigma-Aldrich | M137 | Methysergide maleate salt solid | 2mg | $91.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 5.06419 | Methysergide Maleate - CAS 129-49-7 - Calbiochem | 10mg | $201 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP409 | Methysergide maleate British Pharmacopoeia (BP) Reference Standard | 50MG | $210 | 2022-05-15 | Buy |
| Sigma-Aldrich | 1440003 | Methysergide maleate United States Pharmacopeia (USP) Reference Standard | 350mg | $289 | 2024-03-01 | Buy |
| Sigma-Aldrich | M137 | Methysergide maleate salt solid | 10mg | $308 | 2024-03-01 | Buy |
| Sigma-Aldrich | M137 | Methysergide maleate salt solid | 50mg | $1050 | 2024-03-01 | Buy |
| Tocris | 1064 | Methysergide maleate ≥99%(HPLC) | 10 | $227 | 2021-12-16 | Buy |
Properties
storage temp. :Store at RT
solubility :DMSO: >10 mg/mL
form :solid
color :white to off-white
Water Solubility :Soluble to 10 mM in water with gentle warming
Stability :Hygroscopic
solubility :DMSO: >10 mg/mL
form :solid
color :white to off-white
Water Solubility :Soluble to 10 mM in water with gentle warming
Stability :Hygroscopic
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Methysergide is an agonist of the serotonin (5-HT) receptor subtype 5-HT1 and an antagonist of 5-HT2 receptors. It binds to recombinant human 5-HT1A (KD = 23.44 nM), 5-HT1E (Ki = 229.09 nM), 5-HT1F (Ki = 33.88 nM), and rodent 5-HT1B receptors (KD = 1,513.56 nM). It also binds to recombinant human 5-HT2A (Ki = 2.69 nM) and 5-HT2C receptors (KD = 1.26 nM) and is an insurmountable antagonist at 5-HT2B receptors. It inhibits vasoconstriction induced by 5-HT in isolated postmortem human basilar arterial spiral strips (pA2 = 8.07). Methysergide decreases external carotid blood flow in a dose-dependent manner in vagosympathectomized dogs, an effect that is inhibited by the 5-HT1B/1D receptor antagonist GR127935 . It has antinociceptive activity in mouse models of pain induced by intrathecal injection of substance P , glutamate, NMDA , AMPA , or kainic acid. Methysergide reduces zymosan-induced paw edema in rats when administered at a dose of 10 mg/kg. Formulations containing methysergide were previously used in the prevention and treatment of vascular headaches.Related product price
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