MITHRAMYCIN A
|
- $49 - $1367
- Product name: MITHRAMYCIN A
- CAS: 18378-89-7
- MF: C52H76O24
- MW: 1085.15
- EINECS:634-048-4
- MDL Number:MFCD00135618
- Synonyms:AUREOLIC ACID;METHRAMYCIN A;MITHRAMYCIN A, FOR FLUORESCENCE;MITHRAMYCIN A FROM STREPTOMYCES*PLICATUS APPROX. 96;MITHRAMYCIN COMPLEX FROM STREPTOMYCES*PL ICATUS;MITHRAMYCIN FROM STREPTOMYCES PLICATUS;MITHRACIN;MITHRAMYCIN A
27 prices
Selected condition：
Brand
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 10mM*1mLinDMSO(Solution)
- 1
- 1ml
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 25mg
- ManufacturerApexBio Technology
- Product numberA4546
- Product descriptionMithramycinA
- Packaging5mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4546
- Product descriptionMithramycin A
- Packaging5mg
- Price$371
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycinAfromStreptomycesargillaceus
- Packaging25mg
- Price$923
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycinAfromStreptomycesargillaceus
- Packaging5mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycinAfromStreptomycesargillaceus
- Packaging1mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging5mg
- Price$582
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging10mg
- Price$855
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$1020
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging10mM*1mLinDMSO(Solution)
- Price$1020
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging25mg
- Price$1367
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging1mg
- Price$174
- Updated2026-05-26
- Buy
- ManufacturerAvaChem
- Product number6531
- Product descriptionMithramycin A 98%
- Packaging5mg
- Price$165
- Updated2026-05-22
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545970
- Product descriptionMithramycin A >98%
- Packaging1mg
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545970
- Product descriptionMithramycin A >98%
- Packaging5mg
- Price$323
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11434
- Product descriptionMithramycin A ≥98%
- Packaging5mg
- Price$190
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11434
- Product descriptionMithramycin A ≥98%
- Packaging5mg
- Price$209
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | A4546 | MithramycinA | 5mg | $189 | 2021-12-16 | Buy |
| ApexBio Technology | A4546 | Mithramycin A | 5mg | $371 | 2026-05-06 | Buy |
| Apolloscientific | BIM1003 | MithramycinAfromStreptomycesargillaceus | 25mg | $923 | 2021-12-16 | Buy |
| Apolloscientific | BIM1003 | MithramycinAfromStreptomycesargillaceus | 5mg | $240 | 2021-12-16 | Buy |
| Apolloscientific | BIM1003 | MithramycinAfromStreptomycesargillaceus | 1mg | $73 | 2021-12-16 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 5mg | $582 | 2026-05-26 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 10mg | $855 | 2026-05-26 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 10mM*1mLinDMSO(Solid+Solvent) | $1020 | 2026-05-26 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 10mM*1mLinDMSO(Solution) | $1020 | 2026-05-26 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 25mg | $1367 | 2026-05-26 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 1mg | $174 | 2026-05-26 | Buy |
| AvaChem | 6531 | Mithramycin A 98% | 5mg | $165 | 2026-05-22 | Buy |
| Biorbyt Ltd | orb545970 | Mithramycin A >98% | 1mg | $136 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545970 | Mithramycin A >98% | 5mg | $323 | 2021-12-16 | Buy |
| Cayman Chemical | 11434 | Mithramycin A ≥98% | 5mg | $190 | 2024-03-01 | Buy |
| Cayman Chemical | 11434 | Mithramycin A ≥98% | 5mg | $209 | 2026-04-30 | Buy |
Properties
Melting point :180-183 °C
alpha :D20 -51° (c = 0.4 in ethanol)
Boiling point :761.72°C (rough estimate)
Density :1.1576 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml)
form :Powder
pka :4.54±0.60(Predicted)
color :Red to brown
Merck :13,7619
BRN :5236667
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :CFCUWKMKBJTWLW-BMKRNREMNA-N
EPA Substance Registry System :Plicamycin (18378-89-7)
alpha :D20 -51° (c = 0.4 in ethanol)
Boiling point :761.72°C (rough estimate)
Density :1.1576 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml)
form :Powder
pka :4.54±0.60(Predicted)
color :Red to brown
Merck :13,7619
BRN :5236667
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :CFCUWKMKBJTWLW-BMKRNREMNA-N
EPA Substance Registry System :Plicamycin (18378-89-7)
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Mithramycin A is a DNA-binding, anti-tumor and neuroprotective antibiotic originally isolated from S. grieseus that has long been used as a chemotherapeutic agent. It mediates its protective function, in part, by regulating acetylation of histones or transcription factors and, thereby, chromatin accessibility to transcriptional machinery. As a selective Sp1 inhibitor, mithramycin A binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, which inhibits their expression. Mithramycin A (at 10-200 nM) can sensitize tumor cells to TRAIL-induced apoptosis and has been used to selectively target tumor cells in many different cancer models.Related product price
- 1,3-DIHYDROXYNAPHTHALENE
$9-1634.45 - 6-METHOXY-1-NAPHTHOL
$19-2411.64 - 78119-82-1
$17-1634.45
