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ChemicalBook >> CAS DataBase List >> MK8745

MK8745

$24 - $2260
Product name: MK8745
CAS: 885325-71-3
MF: C20H19ClFN5OS
MW: 431.91
EINECS:
MDL Number:MFCD28009367
Synonyms:MK8745;6-[[4-(3-Chloro-2-fluorobenzoyl)piperazin-1-yl]methyl]-N-(thiazol-2-yl)pyridin-2-amine;Methanone, (3-chloro-2-fluorophenyl)[4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-1-piperazinyl]-;(3-chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone. MK-8745;(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanon;CS-1904;MK8745 USP/EP/BP;Inhibitor,inhibit,MK8745,Aurora Kinase,MK-8745,MK 8745,Apoptosis

Price44 Properties Safety Information Description

44 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Medical Isotopes, Inc.
TRC

Package

10mM*1mLinDMSO(Solid+Solvent)
5mg
10mg
10mM(in1mLDMSO)
25mg
10mM*1mLinDMSO(Solution)
50mg
100mg
250MG
1G
10mM(in 1mL DMSO)

Manufactureraablocks
Product numberAA00GU1N
Product descriptionMK-8745 99+%
Packaging5mg
Price$24
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU1N
Product descriptionMK-8745 99+%
Packaging10mg
Price$35
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU1N
Product descriptionMK-8745 99+%
Packaging25mg
Price$83
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU1N
Product descriptionMK-8745 99+%
Packaging50mg
Price$99
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU1N
Product descriptionMK-8745 99+%
Packaging100mg
Price$196
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberP51707
Product descriptionMK-8745 98%
Packaging100MG
Price$435
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberP51707
Product descriptionMK-8745 98%
Packaging250MG
Price$870
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberP51707
Product descriptionMK-8745 98%
Packaging1G
Price$2260
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number2550AH
Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
Packaging50mg
Price$415
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2550AH
Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
Packaging25mg
Price$310
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2550AH
Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
Packaging10mg
Price$194
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2550AH
Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
Packaging5mg
Price$152
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA8807
Product descriptionMK-8745
Packaging10mM(in 1mL DMSO)
Price$60
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA8807
Product descriptionMK-8745
Packaging10mg
Price$72
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA8807
Product descriptionMK-8745
Packaging10mM(in1mLDMSO)
Price$83
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA8807
Product descriptionMK-8745
Packaging50mg
Price$200
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00GU1N	MK-8745 99+%	5mg	$24	2026-05-28	Buy
aablocks	AA00GU1N	MK-8745 99+%	10mg	$35	2026-05-28	Buy
aablocks	AA00GU1N	MK-8745 99+%	25mg	$83	2026-05-28	Buy
aablocks	AA00GU1N	MK-8745 99+%	50mg	$99	2026-05-28	Buy
aablocks	AA00GU1N	MK-8745 99+%	100mg	$196	2026-05-28	Buy
ACHEMBLOCK	P51707	MK-8745 98%	100MG	$435	2026-05-27	Buy
ACHEMBLOCK	P51707	MK-8745 98%	250MG	$870	2026-05-27	Buy
ACHEMBLOCK	P51707	MK-8745 98%	1G	$2260	2026-05-27	Buy
AK Scientific	2550AH	(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone	50mg	$415	2021-12-16	Buy
AK Scientific	2550AH	(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone	25mg	$310	2021-12-16	Buy
AK Scientific	2550AH	(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone	10mg	$194	2021-12-16	Buy
AK Scientific	2550AH	(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone	5mg	$152	2021-12-16	Buy
ApexBio Technology	A8807	MK-8745	10mM(in 1mL DMSO)	$60	2021-12-16	Buy
ApexBio Technology	A8807	MK-8745	10mg	$72	2026-05-06	Buy
ApexBio Technology	A8807	MK-8745	10mM(in1mLDMSO)	$83	2026-05-06	Buy
ApexBio Technology	A8807	MK-8745	50mg	$200	2026-05-06	Buy

Next Last

Properties

Melting point :177-179°C
Boiling point :605.5±65.0 °C(Predicted)
Density :1.430±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :5.20±0.10(Predicted)
color :Off-White

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

MK-8745 is a potent and selective Aurora A kinase inhibitor that induces apoptotic cell death in a p53-dependent manner when tested in vitro in cell lines of multiple lineages.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

$51.00
MK-8745 CAS:885325-71-3

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MK8745

Properties

Safety Information

Description

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