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ChemicalBook >> CAS DataBase List >> ML-180

ML-180

ML-180 price.
  • $37 - $2000
  • Product name: ML-180
  • CAS: 863588-32-3
  • MF: C20H25ClN4O2
  • MW: 388.89
  • EINECS:
  • MDL Number:MFCD05894342
  • Synonyms:ML-180;SR1848;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;SR1848 >=98% (HPLC);ML-180 (SR1848);6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione
Price36 Properties Safety Information Description
36 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Biorbyt Ltd
  • Cayman Chemical
  • CSNpharm
  • DC Chemicals
Package
  • 001
  • 1mg
  • 1mlx10mM(inDMSO)
  • 10mg
  • 2mg
  • 5mg
  • 002
  • 003
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5289
  • Product descriptionML180
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging50mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging100mg
  • Price$339
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging250mg
  • Price$633
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging1g
  • Price$1629
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1219596
  • Product descriptionML-180 >98%(HPLC)
  • Packaging100mg
  • Price$770
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1219596
  • Product descriptionML-180 >98%(HPLC)
  • Packaging10mg
  • Price$180
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1309410
  • Product descriptionML-180 99.74%
  • Packaging25mg
  • Price$260
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1219596
  • Product descriptionML-180 >98%(HPLC)
  • Packaging25mg
  • Price$310
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1309410
  • Product descriptionML-180 99.74%
  • Packaging50mg
  • Price$430
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1219596
  • Product descriptionML-180 >98%(HPLC)
  • Packaging50mg
  • Price$520
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1309410
  • Product descriptionML-180 99.74%
  • Packaging100mg
  • Price$620
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1219596
  • Product descriptionML-180 >98%(HPLC)
  • Packaging2mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1309410
  • Product descriptionML-180 99.74%
  • Packaging2mg
  • Price$90
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5289 ML180 10mg $160 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 5mg $60 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 10mg $96 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 50mg $189 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 100mg $339 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 250mg $633 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 1g $1629 2021-12-16 Buy
Biorbyt Ltd orb1219596 ML-180 >98%(HPLC) 100mg $770 2026-05-06 Buy
Biorbyt Ltd orb1219596 ML-180 >98%(HPLC) 10mg $180 2026-05-06 Buy
Biorbyt Ltd orb1309410 ML-180 99.74% 25mg $260 2026-05-06 Buy
Biorbyt Ltd orb1219596 ML-180 >98%(HPLC) 25mg $310 2026-05-06 Buy
Biorbyt Ltd orb1309410 ML-180 99.74% 50mg $430 2026-05-06 Buy
Biorbyt Ltd orb1219596 ML-180 >98%(HPLC) 50mg $520 2026-05-06 Buy
Biorbyt Ltd orb1309410 ML-180 99.74% 100mg $620 2026-05-06 Buy
Biorbyt Ltd orb1219596 ML-180 >98%(HPLC) 2mg $90 2026-05-06 Buy
Biorbyt Ltd orb1309410 ML-180 99.74% 2mg $90 2026-05-06 Buy
Next Last

Properties

Density :1.312±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 10 mg/ml
form :A crystalline solid
pka :9.37±0.40(Predicted)
color :Off-white to light yellow
InChI :InChI=1S/C20H25ClN4O2/c21-15-5-4-8-17(13-15)23-9-11-24(12-10-23)18-14-19(26)25(20(27)22-18)16-6-2-1-3-7-16/h4-5,8,13-14,16H,1-3,6-7,9-12H2,(H,22,27)
InChIKey :CHMQQIFPOIZPIJ-UHFFFAOYSA-N
SMILES :C1(=O)NC(N2CCN(C3=CC=CC(Cl)=C3)CC2)=CC(=O)N1C1CCCCC1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).

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Suppliers and manufacturers

TargetMol Chemicals Inc.
ML-180
$70.00 /5mg
ML-180 CAS:863588-32-3
TargetMol Chemicals Inc.
ML-180
$70.00 /5mg
ML-180 CAS:863588-32-3
ATK CHEMICAL COMPANY LIMITED
Career Henan Chemica Co
Hangzhou MolCore BioPharmatech Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd Jingmo (Xiamen) Biotechnology Co., Ltd