ML 351
|
- $59 - $1600
- Product name: ML 351
- CAS: 847163-28-4
- MF: C15H11N3O
- MW: 249.27
- EINECS:
- MDL Number:MFCD04183120
- Synonyms:ML 351;5-(Methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile;4-Oxazolecarbonitrile, 5-(methylamino)-2-(1-naphthalenyl)-;Subarachnoid hemorrhage,inhibit,oxidative stress,ML-351,SAH,neuronal,Lipoxygenase,LOX,T1D,β-cell,ML 351,ML351,Inhibitor,non-obese diabetic;5-(Methylamino)-2-(naphthalen-1-yl)oxazole-4-carbonitrile;ML351, 10 mM in DMSO;12/15-Lipoxygenase Inhibitor, ML351;ML351 NEW
39 prices
Selected condition：
Brand
- A1 Biochem Labs
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
Package
- 25
- 1mg
- 5mg
- 25mg
- 5
- 10mg
- 50mg
- 100mg
- 250mg
- 500.00mg
- 0.5g
- 1.00g
- 1g
- 10 mg
- 25 mg
- ManufacturerA1 Biochem Labs
- Product number6581348
- Product description5-Methylamino-2-naphthalen-1-yl-oxazole-4-carbonitrile 95%
- Packaging1g
- Price$550
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA00GALQ
- Product descriptionML351 95%
- Packaging100mg
- Price$318
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GALQ
- Product descriptionML351 95
- Packaging25mg
- Price$318
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GALQ
- Product descriptionML351 95%
- Packaging250mg
- Price$540
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GALQ
- Product descriptionML351 95
- Packaging1mg
- Price$59
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GALQ
- Product descriptionML351 95
- Packaging5mg
- Price$111
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GALQ
- Product descriptionML351 95
- Packaging10mg
- Price$164
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GALQ
- Product descriptionML351 95%
- Packaging1g
- Price$1230
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberV153235
- Product descriptionML351 98%
- Packaging1G
- Price$1085
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV153235
- Product descriptionML351 98%
- Packaging100MG
- Price$215
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number9811CC
- Product description5-(Methylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile
- Packaging5mg
- Price$307
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0003639
- Product descriptionML-351 98.00%
- Packaging5MG
- Price$505.34
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4277
- Product descriptionML351
- Packaging5mg
- Price$145
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4277
- Product descriptionML351
- Packaging1mg
- Price$60
- Updated2026-05-06
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2312
- Product descriptionML 351
- Packaging5mg
- Price$137.5
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2312
- Product descriptionML 351
- Packaging25mg
- Price$467.5
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| A1 Biochem Labs | 6581348 | 5-Methylamino-2-naphthalen-1-yl-oxazole-4-carbonitrile 95% | 1g | $550 | 2021-12-16 | Buy |
| aablocks | AA00GALQ | ML351 95% | 100mg | $318 | 2026-05-28 | Buy |
| aablocks | AA00GALQ | ML351 95 | 25mg | $318 | 2026-05-28 | Buy |
| aablocks | AA00GALQ | ML351 95% | 250mg | $540 | 2026-05-28 | Buy |
| aablocks | AA00GALQ | ML351 95 | 1mg | $59 | 2026-05-28 | Buy |
| aablocks | AA00GALQ | ML351 95 | 5mg | $111 | 2026-05-28 | Buy |
| aablocks | AA00GALQ | ML351 95 | 10mg | $164 | 2026-05-28 | Buy |
| aablocks | AA00GALQ | ML351 95% | 1g | $1230 | 2026-05-28 | Buy |
| ACHEMBLOCK | V153235 | ML351 98% | 1G | $1085 | 2026-05-27 | Buy |
| ACHEMBLOCK | V153235 | ML351 98% | 100MG | $215 | 2026-05-27 | Buy |
| AK Scientific | 9811CC | 5-(Methylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile | 5mg | $307 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0003639 | ML-351 98.00% | 5MG | $505.34 | 2021-12-16 | Buy |
| ApexBio Technology | C4277 | ML351 | 5mg | $145 | 2026-05-06 | Buy |
| ApexBio Technology | C4277 | ML351 | 1mg | $60 | 2026-05-06 | Buy |
| Axon Medchem | Axon2312 | ML 351 | 5mg | $137.5 | 2026-05-19 | Buy |
| Axon Medchem | Axon2312 | ML 351 | 25mg | $467.5 | 2026-05-19 | Buy |
Properties
Boiling point :507.3±60.0 °C(Predicted)
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≤5mg/ml in DMSO;25mg/ml in dimethyl formamide
pka :-0.97±0.10(Predicted)
form :powder
color :white to beige
InChI :1S/C15H11N3O/c1-17-15-13(9-16)18-14(19-15)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,17H,1H3
InChIKey :DYXYXTDIFMDJIR-UHFFFAOYSA-N
SMILES :CNC1=C(C#N)N=C(O1)C2=C3C(C=CC=C3)=CC=C2
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≤5mg/ml in DMSO;25mg/ml in dimethyl formamide
pka :-0.97±0.10(Predicted)
form :powder
color :white to beige
InChI :1S/C15H11N3O/c1-17-15-13(9-16)18-14(19-15)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,17H,1H3
InChIKey :DYXYXTDIFMDJIR-UHFFFAOYSA-N
SMILES :CNC1=C(C#N)N=C(O1)C2=C3C(C=CC=C3)=CC=C2
Safety Information
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| Signal word: | Danger | ||||||||||||||||
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Description
Lipoxygenases (LOs) are non-heme iron-containing dioxygenases that catalyze the oxidation of polyunsaturated fatty acids to generate unsaturated fatty acid hydroperoxides. The immediate products of 15-LO fatty acid oxidation act as mediators in inflammation, thrombosis, and cancer. ML351 is an inhibitor of human reticulocyte 15-LO-1 (IC50 = 200 nM) with >250-fold selectivity over the related enzymes 5-LO, platelet 12-LO, 15-LO-2, ovine COX-1, and human COX-2. ML351 was shown to be protective against oxidative glutamate toxicity in mouse neuronal HT-22 cells and significantly reduced infarct size in an in vivo mouse model for ischemic stroke.Suppliers and manufacturers
BOC Sciences
Guangzhou Isun Pharmaceutical Co., Ltd
Sigma-Aldrich
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Tianjin Kailiqi Biotechnology Co., Ltd.
Shanghai Chaolan Chemical Technology Center
Beijing Solarbio Science & Tecnology Co., Ltd.
Angel Pharmatech, Ltd.