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ChemicalBook >> CAS DataBase List >> MONOSIALOGANGLIOSIDE GM3

MONOSIALOGANGLIOSIDE GM3

MONOSIALOGANGLIOSIDE GM3 price.
  • $200 - $5750
  • Product name: MONOSIALOGANGLIOSIDE GM3
  • CAS: 54827-14-4
  • MF: C64H118N2O21.H3N
  • MW: 1268.66
  • EINECS:
  • MDL Number:MFCD00131139
  • Synonyms:Monosialoganglioside GM3, Bovine (NH4+ salt);Monosialoganglioside GM3 (bovine)(aMMoniuM salt);Ganglioside M3;Hematoside;Sialosyllactosylceramide;(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-octadecanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid;Ganglioside GM3 (d18:1/18:0);(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-icosanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid
14 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • Biosynth Carbosynth
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 0.5mg
  • 500ug
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-9002-M001
  • Product descriptionGangliosideGM3.sodiumsalt ≥98%(TLC)
  • Packaging1mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberOG175970
  • Product descriptionGM3-Ganglioside ammonium
  • Packaging1mg
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberOG16188
  • Product descriptionGM3-Ganglioside sodium
  • Packaging1mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberOG175970
  • Product descriptionGM3-Ganglioside ammonium
  • Packaging2mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberOG16188
  • Product descriptionGM3-Ganglioside sodium
  • Packaging2mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberOG175970
  • Product descriptionGM3-Ganglioside ammonium
  • Packaging5mg
  • Price$1125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberOG16188
  • Product descriptionGM3-Ganglioside sodium
  • Packaging5mg
  • Price$1375
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberOG16188
  • Product descriptionGM3-Ganglioside sodium
  • Packaging10mg
  • Price$2600
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberOG16188
  • Product descriptionGM3-Ganglioside sodium
  • Packaging25mg
  • Price$5750
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15587
  • Product descriptionGanglioside GM3 (sodium salt) ≥98%
  • Packaging1mg
  • Price$238
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG5642
  • Product descriptionMonosialoganglioside GM3 from canine blood ≥98%, lyophilized powder
  • Packaging0.5mg
  • Price$490
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG5642
  • Product descriptionMonosialoganglioside GM3 from canine blood ≥98%
  • Packaging1mg
  • Price$804
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberM567140
  • Product descriptionMonosialogangliosideGM3SodiumSalt
  • Packaging1mg
  • Price$920
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number297092
  • Product descriptionGM1-Ganglioside
  • Packaging500ug
  • Price$1593
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-9002-M001 GangliosideGM3.sodiumsalt ≥98%(TLC) 1mg $200 2021-12-16 Buy
Biosynth Carbosynth OG175970 GM3-Ganglioside ammonium 1mg $295 2021-12-16 Buy
Biosynth Carbosynth OG16188 GM3-Ganglioside sodium 1mg $320 2021-12-16 Buy
Biosynth Carbosynth OG175970 GM3-Ganglioside ammonium 2mg $550 2021-12-16 Buy
Biosynth Carbosynth OG16188 GM3-Ganglioside sodium 2mg $600 2021-12-16 Buy
Biosynth Carbosynth OG175970 GM3-Ganglioside ammonium 5mg $1125 2021-12-16 Buy
Biosynth Carbosynth OG16188 GM3-Ganglioside sodium 5mg $1375 2021-12-16 Buy
Biosynth Carbosynth OG16188 GM3-Ganglioside sodium 10mg $2600 2021-12-16 Buy
Biosynth Carbosynth OG16188 GM3-Ganglioside sodium 25mg $5750 2021-12-16 Buy
Cayman Chemical 15587 Ganglioside GM3 (sodium salt) ≥98% 1mg $238 2024-03-01 Buy
Sigma-Aldrich G5642 Monosialoganglioside GM3 from canine blood ≥98%, lyophilized powder 0.5mg $490 2024-03-01 Buy
Sigma-Aldrich G5642 Monosialoganglioside GM3 from canine blood ≥98% 1mg $804 2024-03-01 Buy
TRC M567140 MonosialogangliosideGM3SodiumSalt 1mg $920 2021-12-16 Buy
Usbiological 297092 GM1-Ganglioside 500ug $1593 2021-12-16 Buy

Properties

storage temp. :−20°C
solubility :chloroform/methanol/water (9.5:9.5:1): 20mg/mLclear, colorless to light yellow
form :lyophilized powder
color :White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Gangliosides are formed from a glycosphingolipid combined with one or more sialic acids at the oligosaccharide chain. They are anchored at the outer surface of the plasma membrane where they pack densely with cholesterol to form lipid microdomains that modulate both intra- and inter-cell signaling events. Gangliosides are often implicated in tumorigenesis since they can modulate cell surface events including proliferation, migration, and adhesion. Ganglioside GM3 is a simple monosialoganglioside that demonstrates both antiproliferative and proapoptic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. At 20 μM, it can suppress angiogenesis and reduce endothelial cell proliferation and migration by inhibiting VEGFR2 and Akt phosphorylation. Furthermore, ganglioside GM3 has been shown to induce the dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance.

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