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ChemicalBook >> CAS DataBase List >> Mavacamten

Mavacamten

Mavacamten price.
  • $10 - $2841
  • Product name: Mavacamten
  • CAS: 1642288-47-8
  • MF: C15H19N3O2
  • MW: 273.33
  • EINECS:213-161-7
  • MDL Number:MFCD31746877
  • Synonyms:SAR 439152;SAR439152;SAR-439152;SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461; MAVACAMTEN;MYK-461 - Mavacamten | SAR439152;Mavacamten (MYK-461;6-([(1S)-1-phenylethyl]amino)-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione;Mavacamten (SAR-439152
61 prices
Selected condition:
Brand
  • aablocks
  • Abosyn
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
Package
  • 10mM*1mLinDMSO(Solution)
  • 10mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM(in1mLDMSO)
  • 10mM(in 1mL DMSO)
  • 10mM(1mLinDMSO)
  • 1mg
  • 5mg
  • 50mg
  • 25mg
  • 10mM*1mLinDMSO
  • 100.00mg
  • 0.1g
  • 100mg
  • 0.25g
  • 250.00mg
  • 250mg
  • 0.5g
  • 1g
  • 1.00g
  • 5g
  • 10g
  • 25g
  • Manufactureraablocks
  • Product numberAA01EOKL
  • Product descriptionMYK-461 ≥99%
  • Packaging1mg
  • Price$10
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EOKL
  • Product descriptionMYK-461 ≥99%
  • Packaging5mg
  • Price$11
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EOKL
  • Product descriptionMYK-461 ≥99%
  • Packaging25mg
  • Price$22
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EOKL
  • Product descriptionMYK-461 ≥99%
  • Packaging50mg
  • Price$40
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EOKL
  • Product descriptionMYK-461 99%
  • Packaging100mg
  • Price$57
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EOKL
  • Product descriptionMYK-461 99%
  • Packaging250mg
  • Price$97
  • Updated2026-05-30
  • Buy
  • ManufacturerAbosyn
  • Product number90-4805
  • Product description6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches)
  • Packaging0.25g
  • Price$225
  • Updated2026-05-21
  • Buy
  • ManufacturerAbosyn
  • Product number90-4805
  • Product description6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches)
  • Packaging0.5g
  • Price$315
  • Updated2026-05-21
  • Buy
  • ManufacturerAbosyn
  • Product number90-4805
  • Product description6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches)
  • Packaging1g
  • Price$445
  • Updated2026-05-21
  • Buy
  • ManufacturerAbosyn
  • Product number90-4805
  • Product description6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches)
  • Packaging0.1g
  • Price$140
  • Updated2026-05-21
  • Buy
  • ManufacturerAbosyn
  • Product number90-4805
  • Product description6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches)
  • Packaging5g
  • Price$1325
  • Updated2026-05-21
  • Buy
  • ManufacturerAbosyn
  • Product number90-4805
  • Product description6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches)
  • Packaging10g
  • Price$1859
  • Updated2026-05-21
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD251724
  • Product descriptionMYK-461 98%
  • Packaging5G
  • Price$1125
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD251724
  • Product descriptionMYK-461 98%
  • Packaging1G
  • Price$375
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD251724
  • Product descriptionMYK-461 98%
  • Packaging250MG
  • Price$130
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1821EF
  • Product descriptionMavacamten
  • Packaging1mg
  • Price$167
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EOKL MYK-461 ≥99% 1mg $10 2026-05-30 Buy
aablocks AA01EOKL MYK-461 ≥99% 5mg $11 2026-05-30 Buy
aablocks AA01EOKL MYK-461 ≥99% 25mg $22 2026-05-30 Buy
aablocks AA01EOKL MYK-461 ≥99% 50mg $40 2026-05-30 Buy
aablocks AA01EOKL MYK-461 99% 100mg $57 2026-05-30 Buy
aablocks AA01EOKL MYK-461 99% 250mg $97 2026-05-30 Buy
Abosyn 90-4805 6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches) 0.25g $225 2026-05-21 Buy
Abosyn 90-4805 6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches) 0.5g $315 2026-05-21 Buy
Abosyn 90-4805 6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches) 1g $445 2026-05-21 Buy
Abosyn 90-4805 6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches) 0.1g $140 2026-05-21 Buy
Abosyn 90-4805 6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches) 5g $1325 2026-05-21 Buy
Abosyn 90-4805 6-{[(1S)-1-phenylethyl]amino}-3-(prop-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione >95%(Puritymayvarybetweenbatches) 10g $1859 2026-05-21 Buy
ACHEMBLOCK AD251724 MYK-461 98% 5G $1125 2026-05-27 Buy
ACHEMBLOCK AD251724 MYK-461 98% 1G $375 2026-05-27 Buy
ACHEMBLOCK AD251724 MYK-461 98% 250MG $130 2026-05-27 Buy
AK Scientific 1821EF Mavacamten 1mg $167 2021-12-16 Buy

Properties

Density :1.19±0.1 g/cm3(Predicted)
storage temp. :Storage temp. -20°C
solubility :insoluble in H2O; ≥11.32 mg/mL in EtOH with ultrasonic; ≥13.65 mg/mL in DMSO
form :solid
pka :8.83±0.40(Predicted)
color :White to off-white
InChI :InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1
InChIKey :RLCLASQCAPXVLM-NSHDSACASA-N
SMILES :C1(=O)NC(N[C@H](C2=CC=CC=C2)C)=CC(=O)N1C(C)C

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

Mavacamten(MYK-461)is a first-in-class allosteric inhibitor of cardiac myosin that promises to provide clinicians with targeted therapy for these patients. It is a mechanistically novel small molecule that acts on the sarcolemma to specifically inhibit contractility and has been proposed as a treatment for HCM.

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