Meisoindigo
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- $44 - $2267.27
- Product name: Meisoindigo
- CAS: 97207-47-1
- MF: C17H12N2O2
- MW: 276.29
- EINECS:200-256-5
- MDL Number:MFCD05988503
- Synonyms:1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)-DIONE;3-(1,2-dihydro-2-oxo-3h-indol-3-ylidene)-1,3-dihydro-1-methyl-2h-indol-2-one;MEISOINDIGO;N-methylisoindigotin;Dian III;Methylisoindigotin;Natura-α;Meisoindigo 3-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)-1,3-dihydro-1-methyl-2H-indol-2-one
28 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- Crysdot
- CSNpharm
- DC Chemicals
- TCI Chemical
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- 5G
- 25G
- ManufacturerAK Scientific
- Product numberO777
- Product descriptionMeisoindigo
- Packaging25mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0238265
- Product description1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)DIONE 98.00%
- Packaging25G
- Price$2267.27
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0238265
- Product description1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)DIONE 98.00%
- Packaging5G
- Price$2050.13
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3255
- Product descriptionMeisoindigo
- Packaging50mg
- Price$1298
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1503
- Product descriptionMeisoindigo
- Packaging10mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1503
- Product descriptionMeisoindigo
- Packaging100mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1503
- Product descriptionMeisoindigo
- Packaging1g
- Price$1390
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181286
- Product descriptionMeisoindigo >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181286
- Product descriptionMeisoindigo >98%
- Packaging250mg
- Price$1133.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181286
- Product descriptionMeisoindigo >98%
- Packaging1000mg
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18007
- Product descriptionMeisoindigo ≥95%
- Packaging500μg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18007
- Product descriptionMeisoindigo ≥95%
- Packaging1mg
- Price$78
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18007
- Product descriptionMeisoindigo ≥95%
- Packaging5mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18007
- Product descriptionMeisoindigo ≥95%
- Packaging10mg
- Price$595
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number38083
- Product descriptionMeisoindigo,98%(HPLC) 98%(HPLC)
- Packaging25MG
- Price$271.04
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number38083
- Product descriptionMeisoindigo,98%(HPLC) 98%(HPLC)
- Packaging100MG
- Price$872.48
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | O777 | Meisoindigo | 25mg | $340 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0238265 | 1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)DIONE 98.00% | 25G | $2267.27 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0238265 | 1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)DIONE 98.00% | 5G | $2050.13 | 2021-12-16 | Buy |
| ApexBio Technology | B3255 | Meisoindigo | 50mg | $1298 | 2021-12-16 | Buy |
| AvaChem | 1503 | Meisoindigo | 10mg | $119 | 2021-12-16 | Buy |
| AvaChem | 1503 | Meisoindigo | 100mg | $390 | 2021-12-16 | Buy |
| AvaChem | 1503 | Meisoindigo | 1g | $1390 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181286 | Meisoindigo >98% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181286 | Meisoindigo >98% | 250mg | $1133.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181286 | Meisoindigo >98% | 1000mg | $2245.7 | 2021-12-16 | Buy |
| Cayman Chemical | 18007 | Meisoindigo ≥95% | 500μg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 18007 | Meisoindigo ≥95% | 1mg | $78 | 2024-03-01 | Buy |
| Cayman Chemical | 18007 | Meisoindigo ≥95% | 5mg | $341 | 2024-03-01 | Buy |
| Cayman Chemical | 18007 | Meisoindigo ≥95% | 10mg | $595 | 2024-03-01 | Buy |
| Chem-Impex | 38083 | Meisoindigo,98%(HPLC) 98%(HPLC) | 25MG | $271.04 | 2021-12-16 | Buy |
| Chem-Impex | 38083 | Meisoindigo,98%(HPLC) 98%(HPLC) | 100MG | $872.48 | 2021-12-16 | Buy |
Properties
Melting point :236-237°C
Boiling point :482.0±45.0 °C(Predicted)
Density :1.381±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; insoluble in EtOH; ≥25.85 mg/mL in DMSO with ultrasonic
form :powder to crystal
pka :11.62±0.20(Predicted)
color :Orange to Brown to Dark red
InChI :InChI=1S/C17H12N2O2/c1-19-13-9-5-3-7-11(13)15(17(19)21)14-10-6-2-4-8-12(10)18-16(14)20/h2-9H,1H3,(H,18,20)
InChIKey :QNOCRUSVMMAKSC-UHFFFAOYSA-N
SMILES :N1(C)C2=C(C=CC=C2)C(=C2C3=C(NC2=O)C=CC=C3)C1=O
Boiling point :482.0±45.0 °C(Predicted)
Density :1.381±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; insoluble in EtOH; ≥25.85 mg/mL in DMSO with ultrasonic
form :powder to crystal
pka :11.62±0.20(Predicted)
color :Orange to Brown to Dark red
InChI :InChI=1S/C17H12N2O2/c1-19-13-9-5-3-7-11(13)15(17(19)21)14-10-6-2-4-8-12(10)18-16(14)20/h2-9H,1H3,(H,18,20)
InChIKey :QNOCRUSVMMAKSC-UHFFFAOYSA-N
SMILES :N1(C)C2=C(C=CC=C2)C(=C2C3=C(NC2=O)C=CC=C3)C1=O
Safety Information
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Description
Meisoindigo is a derivative of indirubin that has anticancer activity. It inhibits the growth of NB4, HL-60, and U937 leukemia and primary acute myeloid leukemia (AML) cells when used at concentrations of 5 and 10 μM. It also halts the cell cycle at the G0/G1 phase and induces apoptosis in leukemia cell lines and primary AML cells, induces myeloid differentiation, and potentiates the effects of cytarabine and idarubicin . Meisoindigo (10 μM) also induces apoptosis, decreases adherence, and decreases the expression of vascular cell adhesion molecule-1 (VCAM-1) in ECV304 human vein endothelial cells. Meisoindigo (50-150 mg/kg per day) decreases spleen size in an HL-60 mouse xenograft model of AML in a dose-dependent manner.Related product price
- cis-Octahydro-isoindole
$10-1046.18 - Acetonitrile
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$20-1166.55
