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ChemicalBook >> CAS DataBase List >> Meisoindigo

Meisoindigo

Meisoindigo price.
  • $13 - $2267.27
  • Product name: Meisoindigo
  • CAS: 97207-47-1
  • MF: C17H12N2O2
  • MW: 276.29
  • EINECS:200-256-5
  • MDL Number:MFCD05988503
  • Synonyms:1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)-DIONE;3-(1,2-dihydro-2-oxo-3h-indol-3-ylidene)-1,3-dihydro-1-methyl-2h-indol-2-one;MEISOINDIGO;N-methylisoindigotin;Dian III;Methylisoindigotin;Natura-α;Meisoindigo 3-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)-1,3-dihydro-1-methyl-2H-indol-2-one
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  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biorbyt Ltd
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  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
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  • Usbiological
Package
  • 500μg
  • 1mg
  • 1mlx10mM(inDMSO)
  • 5mg
  • 25.00mg
  • 10mM*1mLinDMSO
  • 2mg
  • 10mg
  • 25mg
  • 50mg
  • 50.00mg
  • 100MG
  • 100.00mg
  • 250mg
  • 500mg
  • 1000mg
  • 1g
  • 5G
  • 25G
  • Manufactureraablocks
  • Product numberAA00IJU8
  • Product descriptionMeisoindigo 98%
  • Packaging25mg
  • Price$45
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IJU8
  • Product descriptionMeisoindigo 98%
  • Packaging10mg
  • Price$29
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IJU8
  • Product descriptionMeisoindigo 98%
  • Packaging5mg
  • Price$21
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IJU8
  • Product descriptionMeisoindigo 98%
  • Packaging1mg
  • Price$13
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IJU8
  • Product descriptionMeisoindigo 98%
  • Packaging50mg
  • Price$74
  • Updated2026-05-29
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  • ManufacturerACHEMBLOCK
  • Product numberO33736
  • Product descriptionMethylisoindigotin 98%
  • Packaging100MG
  • Price$510
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberO33736
  • Product descriptionMethylisoindigotin 98%
  • Packaging25MG
  • Price$210
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product numberO777
  • Product descriptionMeisoindigo
  • Packaging25mg
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0238265
  • Product description1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)DIONE 98.00%
  • Packaging25G
  • Price$2267.27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0238265
  • Product description1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)DIONE 98.00%
  • Packaging5G
  • Price$2050.13
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB3255
  • Product descriptionMeisoindigo
  • Packaging50mg
  • Price$1298
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB3255
  • Product descriptionMeisoindigo
  • Packaging2mg
  • Price$70
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3255
  • Product descriptionMeisoindigo
  • Packaging5mg
  • Price$88
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3255
  • Product descriptionMeisoindigo
  • Packaging10mg
  • Price$121
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3255
  • Product descriptionMeisoindigo
  • Packaging50mg
  • Price$363
  • Updated2026-05-06
  • Buy
  • ManufacturerAvaChem
  • Product number1503
  • Product descriptionMeisoindigo
  • Packaging100mg
  • Price$390
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00IJU8 Meisoindigo 98% 25mg $45 2026-05-29 Buy
aablocks AA00IJU8 Meisoindigo 98% 10mg $29 2026-05-29 Buy
aablocks AA00IJU8 Meisoindigo 98% 5mg $21 2026-05-29 Buy
aablocks AA00IJU8 Meisoindigo 98% 1mg $13 2026-05-29 Buy
aablocks AA00IJU8 Meisoindigo 98% 50mg $74 2026-05-29 Buy
ACHEMBLOCK O33736 Methylisoindigotin 98% 100MG $510 2026-05-27 Buy
ACHEMBLOCK O33736 Methylisoindigotin 98% 25MG $210 2026-05-27 Buy
AK Scientific O777 Meisoindigo 25mg $340 2021-12-16 Buy
American Custom Chemicals Corporation CHM0238265 1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)DIONE 98.00% 25G $2267.27 2021-12-16 Buy
American Custom Chemicals Corporation CHM0238265 1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)DIONE 98.00% 5G $2050.13 2021-12-16 Buy
ApexBio Technology B3255 Meisoindigo 50mg $1298 2021-12-16 Buy
ApexBio Technology B3255 Meisoindigo 2mg $70 2026-05-06 Buy
ApexBio Technology B3255 Meisoindigo 5mg $88 2026-05-06 Buy
ApexBio Technology B3255 Meisoindigo 10mg $121 2026-05-06 Buy
ApexBio Technology B3255 Meisoindigo 50mg $363 2026-05-06 Buy
AvaChem 1503 Meisoindigo 100mg $390 2021-12-16 Buy

Properties

Melting point :236-237°C
Boiling point :482.0±45.0 °C(Predicted)
Density :1.381±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; insoluble in EtOH; ≥25.85 mg/mL in DMSO with ultrasonic
form :powder to crystal
pka :11.62±0.20(Predicted)
color :Orange to Brown to Dark red
InChI :InChI=1S/C17H12N2O2/c1-19-13-9-5-3-7-11(13)15(17(19)21)14-10-6-2-4-8-12(10)18-16(14)20/h2-9H,1H3,(H,18,20)
InChIKey :QNOCRUSVMMAKSC-UHFFFAOYSA-N
SMILES :N1(C)C2=C(C=CC=C2)C(=C2C3=C(NC2=O)C=CC=C3)C1=O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Meisoindigo is a derivative of indirubin that has anticancer activity. It inhibits the growth of NB4, HL-60, and U937 leukemia and primary acute myeloid leukemia (AML) cells when used at concentrations of 5 and 10 μM. It also halts the cell cycle at the G0/G1 phase and induces apoptosis in leukemia cell lines and primary AML cells, induces myeloid differentiation, and potentiates the effects of cytarabine and idarubicin . Meisoindigo (10 μM) also induces apoptosis, decreases adherence, and decreases the expression of vascular cell adhesion molecule-1 (VCAM-1) in ECV304 human vein endothelial cells. Meisoindigo (50-150 mg/kg per day) decreases spleen size in an HL-60 mouse xenograft model of AML in a dose-dependent manner.

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