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ChemicalBook >> CAS DataBase List >> Mizolastine

Mizolastine

Mizolastine price.
  • $29 - $1686.3
  • Product name: Mizolastine
  • CAS: 108612-45-9
  • MF: C24H25FN6O
  • MW: 432.49
  • EINECS:1308068-626-2
  • MDL Number:MFCD23140913
  • Synonyms:4(1h)-pyrimidinone,2-((1-(1-((4-fluorophenyl)methyl)-1h-benzimidazol-2-yl)-4-p ;iperidinyl)methylamino)- ;2-[[1-[1-[(4-fluorophenyl)methyl]benzoimidazol-2-yl]-4-piperidyl]-methyl-amino]-3h-pyrimidin-4-one;MIZOLASTINE;2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(1H)-pyrimidinone;Mizolastine HCl;2-[[1-[1-(4-fluorobenzyl)benzimidazol-2-yl]-4-piperidyl]-methyl-amino]-1H-pyrimidin-6-one;2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methyl-amino]-1H-pyrimidin-6-one
22 prices
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Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TCI Chemical
  • TRC
Package
  • 10mg
  • 25MG
  • 50mg
  • 0.1g
  • 100MG
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAHH
  • Product numberAPI-1754
  • Product descriptionMizolastine 98%
  • Packaging0.1g
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ98981
  • Product descriptionMizolastine
  • Packaging1g
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003411
  • Product descriptionMIZOLASTINE 95.00%
  • Packaging25MG
  • Price$160.65
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003411
  • Product descriptionMIZOLASTINE 95.00%
  • Packaging100MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003411
  • Product descriptionMIZOLASTINE 95.00%
  • Packaging1G
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1551
  • Product descriptionMizolastine
  • Packaging50mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2246
  • Product descriptionMizolastine
  • Packaging10mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2246
  • Product descriptionMizolastine
  • Packaging100mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2246
  • Product descriptionMizolastine
  • Packaging1g
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2246
  • Product descriptionMizolastine
  • Packaging5g
  • Price$239
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number38076
  • Product descriptionMizolastine,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC)
  • Packaging1G
  • Price$150.08
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number38076
  • Product descriptionMizolastine,≥98%(Assaybytitration,HPLC) ≥98%(Assaybytitration,HPLC)
  • Packaging5G
  • Price$589.39
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-1997
  • Product descriptionMizolastine 99.33%
  • Packaging100mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1997
  • Product descriptionMizolastine 99.33%
  • Packaging200mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1997
  • Product descriptionMizolastine 99.33%
  • Packaging500mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004620
  • Product descriptionMizolastine 98+%
  • Packaging100mg
  • Price$73
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1754 Mizolastine 98% 0.1g $370 2021-12-16 Buy
AK Scientific J98981 Mizolastine 1g $80 2021-12-16 Buy
American Custom Chemicals Corporation API0003411 MIZOLASTINE 95.00% 25MG $160.65 2021-12-16 Buy
American Custom Chemicals Corporation API0003411 MIZOLASTINE 95.00% 100MG $716.1 2021-12-16 Buy
American Custom Chemicals Corporation API0003411 MIZOLASTINE 95.00% 1G $1686.3 2021-12-16 Buy
ApexBio Technology B1551 Mizolastine 50mg $68 2021-12-16 Buy
AvaChem 2246 Mizolastine 10mg $29 2021-12-16 Buy
AvaChem 2246 Mizolastine 100mg $59 2021-12-16 Buy
AvaChem 2246 Mizolastine 1g $79 2021-12-16 Buy
AvaChem 2246 Mizolastine 5g $239 2021-12-16 Buy
Chem-Impex 38076 Mizolastine,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC) 1G $150.08 2021-12-16 Buy
Chem-Impex 38076 Mizolastine,≥98%(Assaybytitration,HPLC) ≥98%(Assaybytitration,HPLC) 5G $589.39 2021-12-16 Buy
ChemScene CS-1997 Mizolastine 99.33% 100mg $125 2021-12-16 Buy
ChemScene CS-1997 Mizolastine 99.33% 200mg $226 2021-12-16 Buy
ChemScene CS-1997 Mizolastine 99.33% 500mg $400 2021-12-16 Buy
Crysdot CD31004620 Mizolastine 98+% 100mg $73 2021-12-16 Buy

Properties

Melting point :217°
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly, Heated), DMSO, Methanol (Slightly, Heated)
form :Solid
pka :9.73±0.40(Predicted)
color :White
Merck :14,6221

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

Mizolastine was marketed in Germany and Switzerland as Mizollen for the symptomatic relief of seasonal and perennial allergic rhinoconjunctivitis and urticaria. Mizolastine is a new long-acting, orally active antihistaminic agent with a rapid onset of action ; the two most recent H1 antagonists launched were fexofenadine, metabolite of terfenadine (Sepracor, 1996) and Olopatadine (Kyowa Hakko, 1997). Mizolastine can be prepared in 2 steps from 2-chloro 1- (4-fluorobenzyl)benzimidazole by successive condensations of appropriate amine and thioether. Mizolastine selectively blocks the peripheral H1 receptors (but not the serotonergic, noradrenergic, muscarinic receptors) with a minimal occupancy of brain receptors, and therefore does not elicit any sedative effects. Moreover, Mizolastine does not produce cardiac rhythm disorders which have been associated with certain non-sedating antihistamines in humans.

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