NO-1886
|
- $18 - $1900
- Product name: NO-1886
- CAS: 133208-93-2
- MF: C19H20BrN2O4P
- MW: 451.25
- EINECS:
- MDL Number:MFCD00897807
- Synonyms:OPF 009;Lipoprotein Lipase Activator;NO-1886;Diethyl 4-[(4-bromo-2-cyanophenyl)carbamoyl]benzylphosphonate;4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide;Diethyl 4-[(4-bromo-2-cyanophenyl)carbamoyl]benzylphosphonate, Ibrolipim, OPF 009;Ibrolipim NO-1886;N-(4-bromo-2-cyanophenyl)-4-(diethoxyphosphorylmethyl)benzamide
39 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- Arctom
- Cayman Chemical
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 003
- 1G
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA0014BO
- Product descriptionDiethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99%
- Packaging5mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0014BO
- Product descriptionDiethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99%
- Packaging10mg
- Price$40
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0014BO
- Product descriptionDiethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99%
- Packaging1mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0014BO
- Product descriptionDiethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99%
- Packaging25mg
- Price$75
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0014BO
- Product descriptionDiethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99
- Packaging100mg
- Price$228
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109953
- Product descriptionIbrolipi 98.00%
- Packaging1G
- Price$895
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU109953
- Product descriptionIbrolipi 98.00%
- Packaging100MG
- Price$285
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4408BA
- Product descriptionIbrolipim
- Packaging50mg
- Price$169
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4408BA
- Product descriptionIbrolipim
- Packaging5mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4408BA
- Product descriptionIbrolipim
- Packaging10mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4408BA
- Product descriptionIbrolipim
- Packaging25mg
- Price$143
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA644717
- Product descriptionDiethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97%
- Packaging1mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA644717
- Product descriptionDiethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97%
- Packaging10mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA644717
- Product descriptionDiethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97%
- Packaging5mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA644717
- Product descriptionDiethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97%
- Packaging50mg
- Price$157
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA644717
- Product descriptionDiethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97%
- Packaging25mg
- Price$106
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0014BO | Diethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99% | 5mg | $27 | 2026-05-28 | Buy |
| aablocks | AA0014BO | Diethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99% | 10mg | $40 | 2026-05-28 | Buy |
| aablocks | AA0014BO | Diethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99% | 1mg | $18 | 2026-05-28 | Buy |
| aablocks | AA0014BO | Diethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99% | 25mg | $75 | 2026-05-28 | Buy |
| aablocks | AA0014BO | Diethyl [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]phosphonate 99 | 100mg | $228 | 2026-05-28 | Buy |
| ACHEMBLOCK | U109953 | Ibrolipi 98.00% | 1G | $895 | 2026-05-27 | Buy |
| ACHEMBLOCK | U109953 | Ibrolipi 98.00% | 100MG | $285 | 2026-05-27 | Buy |
| AK Scientific | 4408BA | Ibrolipim | 50mg | $169 | 2021-12-16 | Buy |
| AK Scientific | 4408BA | Ibrolipim | 5mg | $108 | 2021-12-16 | Buy |
| AK Scientific | 4408BA | Ibrolipim | 10mg | $124 | 2021-12-16 | Buy |
| AK Scientific | 4408BA | Ibrolipim | 25mg | $143 | 2021-12-16 | Buy |
| Ambeed | A644717 | Diethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97% | 1mg | $19 | 2021-12-16 | Buy |
| Ambeed | A644717 | Diethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97% | 10mg | $63 | 2021-12-16 | Buy |
| Ambeed | A644717 | Diethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97% | 5mg | $42 | 2021-12-16 | Buy |
| Ambeed | A644717 | Diethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97% | 50mg | $157 | 2021-12-16 | Buy |
| Ambeed | A644717 | Diethyl4-((4-bromo-2-cyanophenyl)carbamoyl)benzylphosphonate 97% | 25mg | $106 | 2021-12-16 | Buy |
Properties
Melting point :160.5-162.1 °C
Boiling point :512.5±50.0 °C(Predicted)
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥20mg/mL
form :powder
pka :11.51±0.70(Predicted)
color :off-white to pale yellow
InChI :1S/C19H20BrN2O4P/c1-3-25-27(24,26-4-2)13-14-5-7-15(8-6-14)19(23)22-18-10-9-17(20)11-16(18)12-21/h5-11H,3-4,13H2,1-2H3,(H,22,23)
InChIKey :KPRTURMJVWXURQ-UHFFFAOYSA-N
SMILES :CCOP(=O)(Cc1ccc(cc1)C(=O)Nc2ccc(Br)cc2C#N)OCC
Boiling point :512.5±50.0 °C(Predicted)
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥20mg/mL
form :powder
pka :11.51±0.70(Predicted)
color :off-white to pale yellow
InChI :1S/C19H20BrN2O4P/c1-3-25-27(24,26-4-2)13-14-5-7-15(8-6-14)19(23)22-18-10-9-17(20)11-16(18)12-21/h5-11H,3-4,13H2,1-2H3,(H,22,23)
InChIKey :KPRTURMJVWXURQ-UHFFFAOYSA-N
SMILES :CCOP(=O)(Cc1ccc(cc1)C(=O)Nc2ccc(Br)cc2C#N)OCC
Safety Information
| Symbol(GHS): |
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| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
Lipoprotein lipase (LPL) mediates the hydrolysis of triglycerides in circulating very low density lipoproteins and chylomicrons. NO-1886 is an LPL activator that increases LPL mRNA and LPL activity in adipose tissue, myocardium, and skeletal muscle. This coincides with an elevation in post-heparin plasma LPL activity and LPL mass in rats. NO-1886 decreases plasma triglyceride concentration and increases plasma high-density lipoprotein cholesterol, resulting in inhibited development of atherosclerotic lesions in coronary arteries and aortas of rats and rabbits.Related product price
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