NPPB
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- $37 - $1320
- Product name: NPPB
- CAS: 107254-86-4
- MF: C16H16N2O4
- MW: 300.31
- EINECS:
- MDL Number:MFCD00153851
- Synonyms:5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID;5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID;NPPB;5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC A CID POTENT CHLORIDE CHANN;5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 98%;3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid;Compound 144;C13705
56 prices
Selected condition：
Brand
- ACHEMBLOCK
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Synthonix
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10μg
- 5mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 50
- 25mg
- 50.00mg
- 100.00mg
- 250.00mg
- 10mM(in1mLDMSO)
- 10mg
- 50mg
- 10mM*1mLinDMSO(Solution)
- 100MG
- 250MG
- 1G
- 10mM(in 1mL DMSO)
- ManufacturerACHEMBLOCK
- Product numberY229286
- Product descriptionNPPB 97.00%
- Packaging100MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229286
- Product descriptionNPPB 97.00%
- Packaging250MG
- Price$185
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229286
- Product descriptionNPPB 97.00%
- Packaging1G
- Price$555
- Updated2026-05-27
- Buy
- ManufacturerAmbeed
- Product numberA336852
- Product description5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+%
- Packaging250mg
- Price$319
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA336852
- Product description5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+%
- Packaging100mg
- Price$213
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA336852
- Product description5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+%
- Packaging1g
- Price$1085
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA336852
- Product description5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+%
- Packaging50mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA336852
- Product description5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+%
- Packaging10mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0012827
- Product description5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 95.00%
- Packaging50MG
- Price$702.19
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6367
- Product descriptionNPPB
- Packaging10mM(in1mLDMSO)
- Price$193
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6367
- Product descriptionNPPB
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6367
- Product descriptionNPPB
- Packaging50mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6367
- Product descriptionNPPB
- Packaging50mg
- Price$187
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-101012
- Product descriptionNPPB 99.78%
- Packaging50mg
- Price$183
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101012
- Product descriptionNPPB 99.78%
- Packaging10mM*1mLinDMSO(Solution)
- Price$39
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101012
- Product descriptionNPPB 99.78%
- Packaging5mg
- Price$37
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | Y229286 | NPPB 97.00% | 100MG | $145 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y229286 | NPPB 97.00% | 250MG | $185 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y229286 | NPPB 97.00% | 1G | $555 | 2026-05-27 | Buy |
| Ambeed | A336852 | 5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+% | 250mg | $319 | 2021-12-16 | Buy |
| Ambeed | A336852 | 5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+% | 100mg | $213 | 2021-12-16 | Buy |
| Ambeed | A336852 | 5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+% | 1g | $1085 | 2021-12-16 | Buy |
| Ambeed | A336852 | 5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+% | 50mg | $164 | 2021-12-16 | Buy |
| Ambeed | A336852 | 5-Nitro-2-(3-phenylpropylamino)benzoic Acid 98+% | 10mg | $98 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0012827 | 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 95.00% | 50MG | $702.19 | 2021-12-16 | Buy |
| ApexBio Technology | B6367 | NPPB | 10mM(in1mLDMSO) | $193 | 2026-05-06 | Buy |
| ApexBio Technology | B6367 | NPPB | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B6367 | NPPB | 50mg | $170 | 2021-12-16 | Buy |
| ApexBio Technology | B6367 | NPPB | 50mg | $187 | 2026-05-06 | Buy |
| Arctom | HY-101012 | NPPB 99.78% | 50mg | $183 | 2026-05-26 | Buy |
| Arctom | HY-101012 | NPPB 99.78% | 10mM*1mLinDMSO(Solution) | $39 | 2026-05-26 | Buy |
| Arctom | HY-101012 | NPPB 99.78% | 5mg | $37 | 2026-05-26 | Buy |
Properties
Melting point :178-180℃
Boiling point :523.5±50.0 °C(Predicted)
Density :1.323±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :ethanol: 3 mg/mL
pka :2.27±0.22(Predicted)
form :Yellow solid
color :Light yellow to yellow
InChI :1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)
InChIKey :WBSMIPAMAXNXFS-UHFFFAOYSA-N
SMILES :OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+]([O-])=O
Boiling point :523.5±50.0 °C(Predicted)
Density :1.323±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :ethanol: 3 mg/mL
pka :2.27±0.22(Predicted)
form :Yellow solid
color :Light yellow to yellow
InChI :1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)
InChIKey :WBSMIPAMAXNXFS-UHFFFAOYSA-N
SMILES :OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+]([O-])=O
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist. It has been shown to activate the GPR35-Gαi/o and GPR35-Gα16 pathways in HEK293 cells, inducing intracellular calcium mobilization. NPPB has protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes.More related product prices
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