NPS 2390
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- $12 - $6561
- Product name: NPS 2390
- CAS: 226878-01-9
- MF: C19H21N3O
- MW: 307.39
- EINECS:
- MDL Number:MFCD05865239
- Synonyms:N-tricyclo[3.3.1.13,7]dec-1-yl-2-quinoxalinecarboxamide;N-(1-adamantyl)quinoxaline-2-carboxamide;N-(Adamantan-1-yl)quinoxaline-2-carboxamide;Inhibitor,NPS2390,Calcium-sensing receptor,NPS-2390,mGluR,inhibit,Metabotropic glutamate receptors,CaSR,NPS 2390;2-Quinoxalinecarboxamide, N-tricyclo[3.3.1.13,7]dec-1-yl-;NPS2390, 10 mM in DMSO
29 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth
- Cayman Chemical
- ChemScene
- CSNpharm
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- 250mg
- Manufactureraablocks
- Product numberAA00BFZ4
- Product descriptionN-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide ≥99%(HPLC)
- Packaging50mg
- Price$68
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BFZ4
- Product descriptionN-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide ≥99%(HPLC)
- Packaging100mg
- Price$123
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BFZ4
- Product descriptionN-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide ≥99%(HPLC)
- Packaging250mg
- Price$268
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BFZ4
- Product descriptionN-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide 98%
- Packaging10mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BFZ4
- Product descriptionN-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide ≥99%(HPLC)
- Packaging5mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BFZ4
- Product descriptionN-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide 98%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX195640
- Product descriptionNPS 2390 98.00%
- Packaging100MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX195640
- Product descriptionNPS 2390 98.00%
- Packaging250MG
- Price$290
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number6596CQ
- Product descriptionN-(1-Adamantyl)quinoxaline-2-carboxamide
- Packaging5mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0003710
- Product descriptionNPS 2390 95.00%
- Packaging5MG
- Price$203.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0003710
- Product descriptionNPS 2390 95.00%
- Packaging25MG
- Price$906.53
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5532
- Product descriptionNPS 2390
- Packaging50mg
- Price$1190
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5532
- Product descriptionNPS 2390
- Packaging25mg
- Price$203
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5532
- Product descriptionNPS 2390
- Packaging10mg
- Price$97
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5532
- Product descriptionNPS 2390
- Packaging5mg
- Price$65
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberBJA87801
- Product descriptionNPS 2390
- Packaging50mg
- Price$6561
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BFZ4 | N-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide ≥99%(HPLC) | 50mg | $68 | 2026-05-28 | Buy |
| aablocks | AA00BFZ4 | N-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide ≥99%(HPLC) | 100mg | $123 | 2026-05-28 | Buy |
| aablocks | AA00BFZ4 | N-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide ≥99%(HPLC) | 250mg | $268 | 2026-05-28 | Buy |
| aablocks | AA00BFZ4 | N-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide 98% | 10mg | $19 | 2026-05-28 | Buy |
| aablocks | AA00BFZ4 | N-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide ≥99%(HPLC) | 5mg | $12 | 2026-05-28 | Buy |
| aablocks | AA00BFZ4 | N-(Adamantan-1-Yl)Quinoxaline-2-Carboxamide 98% | 1mg | $12 | 2026-05-28 | Buy |
| ACHEMBLOCK | X195640 | NPS 2390 98.00% | 100MG | $145 | 2026-05-27 | Buy |
| ACHEMBLOCK | X195640 | NPS 2390 98.00% | 250MG | $290 | 2026-05-27 | Buy |
| AK Scientific | 6596CQ | N-(1-Adamantyl)quinoxaline-2-carboxamide | 5mg | $197 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0003710 | NPS 2390 95.00% | 5MG | $203.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0003710 | NPS 2390 95.00% | 25MG | $906.53 | 2021-12-16 | Buy |
| ApexBio Technology | B5532 | NPS 2390 | 50mg | $1190 | 2026-05-06 | Buy |
| ApexBio Technology | B5532 | NPS 2390 | 25mg | $203 | 2026-05-06 | Buy |
| ApexBio Technology | B5532 | NPS 2390 | 10mg | $97 | 2026-05-06 | Buy |
| ApexBio Technology | B5532 | NPS 2390 | 5mg | $65 | 2026-05-06 | Buy |
| Biosynth | BJA87801 | NPS 2390 | 50mg | $6561 | 2026-06-04 | Buy |
Properties
Boiling point :542.4±30.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble to 50 mM in DMSO and to 50 mM in ethanol
form :Powder
pka :11.53±0.20(Predicted)
color :White to light yellow
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble to 50 mM in DMSO and to 50 mM in ethanol
form :Powder
pka :11.53±0.20(Predicted)
color :White to light yellow
Safety Information
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| Signal word: | Warning | |||||||
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Description
Metabotropic glutamate receptors (mGluRs), mediate excitatory synaptic transmission in the central nervous system. Potent and selective antagonists of the type I mGluRs (mGluR1 and mGluR5) are of interest as novel therapeutics for the treatment of various CNS disorders, such as pain, epilepsy, and stroke. NPS 2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 with IC50 values equal to 5.2 and 82 nM, respectively). At concentrations up to 30 μM, NPS 2390 does not affect mGluR2 or mGluR8 or a standard collection of 37 additional receptors, ion channels, and enzymes. At a dose of 10 mg/kg, NPS 2390 displaced the specifically bound mGlu1R-selective antagonist, [3H]R214127, in rat cerebellum.More related product prices
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NPS 2390
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