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ChemicalBook >> CAS DataBase List >> Nafamostat mesylate

Nafamostat mesylate

Nafamostat mesylate price.
  • $29 - $245
  • Product name: Nafamostat mesylate
  • CAS: 82956-11-4
  • MF: C21H25N5O8S2
  • MW: 539.58
  • EINECS:692-168-2
  • MDL Number:MFCD00941430
  • Synonyms:Nafamostat mesylate Manufacturer/High quality/Best price/In stock CAS NO.82956-11-4;Nafamostat mesila;4-((aminoiminomethyl)amino)-benzoicaci6-(aminoiminomethyl)-2-naphthalenyl ;6-carbaMiMidoylnaphthalen-2-yl 4-guanidinobenzoate diMethanesulfonate;[amino-[6-[[4-(diaminomethyleneazaniumyl)phenyl]-oxomethoxy]-2-naphthyl]methylene]ammonium;[amino-[6-[4-(diaminomethyleneazaniumyl)benzoyl]oxy-2-naphthyl]methylene]ammonium;[amino-[6-[4-(diaminomethylideneazaniumyl)benzoyl]oxynaphthalen-2-yl]methylidene]azanium;[amino-[6-[4-(diaminomethylideneazaniumyl)phenyl]carbonyloxynaphthalen-2-yl]methylidene]azanium
5 prices
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Brand

  • Cayman Chemical
  • TCI Chemical

Package

  • 5mg
  • 10mg
  • 20mg
  • 50mg
  • 100mg
  • ManufacturerCayman Chemical
  • Product number14837
  • Product descriptionNafamostat (mesylate) ≥98%
  • Packaging5mg
  • Price$29
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number14837
  • Product descriptionNafamostat (mesylate) ≥98%
  • Packaging10mg
  • Price$55
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number14837
  • Product descriptionNafamostat (mesylate) ≥98%
  • Packaging50mg
  • Price$245
  • Updated2018-11-13
  • Buy
  • ManufacturerTCI Chemical
  • Product numberN0959
  • Product descriptionNafamostat Mesylate >98.0%(HPLC)
  • Packaging20mg
  • Price$58
  • Updated2018-11-22
  • Buy
  • ManufacturerTCI Chemical
  • Product numberN0959
  • Product descriptionNafamostat Mesylate >98.0%(HPLC)
  • Packaging100mg
  • Price$196
  • Updated2018-11-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 14837 Nafamostat (mesylate) ≥98% 5mg $29 2018-11-13 Buy
Cayman Chemical 14837 Nafamostat (mesylate) ≥98% 10mg $55 2018-11-13 Buy
Cayman Chemical 14837 Nafamostat (mesylate) ≥98% 50mg $245 2018-11-13 Buy
TCI Chemical N0959 Nafamostat Mesylate >98.0%(HPLC) 20mg $58 2018-11-22 Buy
TCI Chemical N0959 Nafamostat Mesylate >98.0%(HPLC) 100mg $196 2018-11-22 Buy

Properties

Melting point: :259-261°C
storage temp.  :Room temp
form  :powder
color  :white to beige
Merck  :14,6350
CAS DataBase Reference :82956-11-4(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P281 Use personal protective equipment as required.

Description

Nafamostat is a serine protease inhibitor that is capable of inhibiting trypsin (a digestive system protease; Ki = 15 nM), tryptase (a mast cell protease; Ki = 95.3 pM), and additional proteases in the coagulation cascade including thrombin (Ki = 0.84 μM). In a mouse model of allergic asthma, a dose of 300 mg/kg nafamostat mesylate has been shown to inhibit serine proteolytic activity, to decrease circulating levels of eosinophils and lymphocytes in bronchoalveolar lavage fluid, and to reduce interleukin-13 and eotaxin production associated with antigen-induced airway eosinophilia and goblet cell hyperplasia.

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