Necrosulfonamide
|
- $14 - $1792
- Product name: Necrosulfonamide
- CAS: 1360614-48-7
- MF: C18H15N5O6S2
- MW: 461.47
- EINECS:
- MDL Number:MFCD02370191
- Synonyms:(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfaMoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylaMide;NecrosulfonaMide;(E)-NECROSULFONAMIDE;(2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide;100318;CS-2351;Necrosulfonamide (NSA);2-Propenamide, N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-, (2E)-
95 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO
- 50
- 100mg
- 250mg
- 1G
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- 50.00g
- 100.00g
- 250.00g
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging1mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging5mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging10mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98%
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging50mg
- Price$77
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging100mg
- Price$115
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98%
- Packaging25mg
- Price$170
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging250mg
- Price$185
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98%
- Packaging50mg
- Price$329
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98%
- Packaging100mg
- Price$409
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging100MG
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging100MG
- Price$295
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging100MG
- Price$295
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging25MG
- Price$110
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging25MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging1G
- Price$1150
- Updated2026-05-25
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009CKI | Necrosulfonamide 98+% | 1mg | $14 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 5mg | $27 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 10mg | $36 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98% | 5mg | $70 | 2021-12-16 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 50mg | $77 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 100mg | $115 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98% | 25mg | $170 | 2021-12-16 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 250mg | $185 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98% | 50mg | $329 | 2021-12-16 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98% | 100mg | $409 | 2021-12-16 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 100MG | $350 | 2021-12-16 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 100MG | $295 | 2026-05-25 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 100MG | $295 | 2026-05-27 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 25MG | $110 | 2026-05-25 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 25MG | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 1G | $1150 | 2026-05-25 | Buy |
Properties
Melting point :200-204°C(dec.)
Density :1.578±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml)
form :solid
pka :6.37±0.40(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Density :1.578±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml)
form :solid
pka :6.37±0.40(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Necrosulfonamide (1360614-48-7) specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5Related product price
-
22120-39-4
$184-4283.4 -
SU 4312
$24-1310 -
Telatinib
$18-8100




