Necrosulfonamide
|
- $14 - $1792
- Product name: Necrosulfonamide
- CAS: 1360614-48-7
- MF: C18H15N5O6S2
- MW: 461.47
- EINECS:
- MDL Number:MFCD02370191
- Synonyms:(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfaMoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylaMide;NecrosulfonaMide;(E)-NECROSULFONAMIDE;(2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide;100318;CS-2351;Necrosulfonamide (NSA);2-Propenamide, N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-, (2E)-
66 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO
- 10
- 100mg
- 250mg
- 1G
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- 50.00g
- 100.00g
- 250.00g
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging1mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging5mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging10mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging50mg
- Price$77
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging100mg
- Price$115
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98%
- Packaging25mg
- Price$170
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA009CKI
- Product descriptionNecrosulfonamide 98+%
- Packaging250mg
- Price$185
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging25MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging100MG
- Price$295
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32766
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98%
- Packaging1G
- Price$1150
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3705-M025
- Product descriptionNecrosulfonamide ≥95%
- Packaging25mg
- Price$160
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3705-M005
- Product descriptionNecrosulfonamide ≥95%
- Packaging5mg
- Price$40
- Updated2026-05-06
- Buy
- ManufacturerAmbeed
- Product numberA750842
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98+%
- Packaging1mg
- Price$31
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA750842
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98+%
- Packaging10mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA750842
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98+%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA750842
- Product description(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98+%
- Packaging25mg
- Price$86
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009CKI | Necrosulfonamide 98+% | 1mg | $14 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 5mg | $27 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 10mg | $36 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 50mg | $77 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 100mg | $115 | 2026-05-28 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98% | 25mg | $170 | 2021-12-16 | Buy |
| aablocks | AA009CKI | Necrosulfonamide 98+% | 250mg | $185 | 2026-05-28 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 25MG | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 100MG | $295 | 2026-05-27 | Buy |
| ACHEMBLOCK | O32766 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98% | 1G | $1150 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-3705-M025 | Necrosulfonamide ≥95% | 25mg | $160 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3705-M005 | Necrosulfonamide ≥95% | 5mg | $40 | 2026-05-06 | Buy |
| Ambeed | A750842 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98+% | 1mg | $31 | 2021-12-16 | Buy |
| Ambeed | A750842 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98+% | 10mg | $66 | 2021-12-16 | Buy |
| Ambeed | A750842 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98+% | 5mg | $50 | 2021-12-16 | Buy |
| Ambeed | A750842 | (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide 98+% | 25mg | $86 | 2021-12-16 | Buy |
Properties
Melting point :200-204°C(dec.)
Density :1.578±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml)
form :solid
pka :6.37±0.40(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Density :1.578±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml)
form :solid
pka :6.37±0.40(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Necrosulfonamide (1360614-48-7) specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
Shanghai Topbiochem Technology Co., Ltd
Zhengzhou HSH Science & Technology Co., Ltd.
Guangzhou Isun Pharmaceutical Co., Ltd
ShangHai Caerulum Pharma Discovery Co., Ltd.
Bide Pharmatech Ltd.
AdooQ Bioscience CHINA
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.