Nelarabine
|
- $12 - $8300
- Product name: Nelarabine
- CAS: 121032-29-9
- MF: C11H15N5O5
- MW: 297.27
- EINECS:642-916-9
- MDL Number:MFCD00871078
- Synonyms:(2R,3S,4S,5R)-2-(2-AMino-6-Methoxy-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol;506U78;(2R,3S,4R,5R)-2-(2-amino-6-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;2-amino-9-β-D-arabinofuranosyl-6-methoxy-9H-purine;NELARABINE;Nelzarabine [USAN];9beta-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine;Nelarabine (Arranon)
82 prices
Selected condition：
Brand
- aablocks
- AccelPharmtech
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 500mg
- 1000mg
- 250.00mg
- 10mM*1mLinDMSO
- 10
- 2000mg
- 100.00g
- 50
- 1.00g
- 50.00g
- 250.00g
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 25mg
- 10G
- 25G
- 1g
- 10mM(in 1mL DMSO)
- Manufactureraablocks
- Product numberAA00HFSB
- Product description9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98%
- Packaging1mg
- Price$12
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00HFSB
- Product description9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98%
- Packaging5mg
- Price$16
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00HFSB
- Product description9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98%
- Packaging10mg
- Price$19
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00HFSB
- Product description9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98%
- Packaging50mg
- Price$67
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00HFSB
- Product description9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98%
- Packaging100mg
- Price$95
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00HFSB
- Product description9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine ≥98%
- Packaging250mg
- Price$195
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00HFSB
- Product description9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine ≥98%
- Packaging1g
- Price$480
- Updated2026-05-29
- Buy
- ManufacturerAccelPharmtech
- Product numberAT6382
- Product descriptionNelarabine 99%
- Packaging10G
- Price$3540
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberAT6382
- Product descriptionNelarabine 99%
- Packaging25G
- Price$8300
- Updated2026-05-21
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228843
- Product descriptionNelarabine 97.00%
- Packaging1G
- Price$710
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228843
- Product descriptionNelarabine 97.00%
- Packaging100MG
- Price$150
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberJ10096
- Product descriptionNelarabine 98%
- Packaging100mg
- Price$161
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10096
- Product descriptionNelarabine
- Packaging5mg
- Price$98.6
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberR077
- Product descriptionNelarabine 95%
- Packaging100mg
- Price$120
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberR077
- Product descriptionNelarabine 95%
- Packaging250mg
- Price$195
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberR077
- Product descriptionNelarabine 95%
- Packaging25mg
- Price$48
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00HFSB | 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98% | 1mg | $12 | 2026-05-29 | Buy |
| aablocks | AA00HFSB | 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98% | 5mg | $16 | 2026-05-29 | Buy |
| aablocks | AA00HFSB | 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98% | 10mg | $19 | 2026-05-29 | Buy |
| aablocks | AA00HFSB | 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98% | 50mg | $67 | 2026-05-29 | Buy |
| aablocks | AA00HFSB | 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine 98% | 100mg | $95 | 2026-05-29 | Buy |
| aablocks | AA00HFSB | 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine ≥98% | 250mg | $195 | 2026-05-29 | Buy |
| aablocks | AA00HFSB | 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine ≥98% | 1g | $480 | 2026-05-29 | Buy |
| AccelPharmtech | AT6382 | Nelarabine 99% | 10G | $3540 | 2026-05-21 | Buy |
| AccelPharmtech | AT6382 | Nelarabine 99% | 25G | $8300 | 2026-05-21 | Buy |
| ACHEMBLOCK | Y228843 | Nelarabine 97.00% | 1G | $710 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228843 | Nelarabine 97.00% | 100MG | $150 | 2026-05-27 | Buy |
| AK Scientific | J10096 | Nelarabine 98% | 100mg | $161 | 2026-06-04 | Buy |
| AK Scientific | J10096 | Nelarabine | 5mg | $98.6 | 2021-12-16 | Buy |
| AK Scientific | R077 | Nelarabine 95% | 100mg | $120 | 2026-06-04 | Buy |
| AK Scientific | R077 | Nelarabine 95% | 250mg | $195 | 2026-06-04 | Buy |
| AK Scientific | R077 | Nelarabine 95% | 25mg | $48 | 2026-06-04 | Buy |
Properties
Melting point :209-217°
alpha :D20 +55.9° (c = 0.27 in DMF)
Boiling point :721.0±70.0 °C(Predicted)
Density :1.98±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly, Sonicated)
form :Solid
pka :13.07±0.70(Predicted)
color :White
Water Solubility :H2O: 5mg/mL, clear (warmed)
InChI :InChI=1/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10-/s3
InChIKey :IXOXBSCIXZEQEQ-GCTRTDOSNA-N
SMILES :N1(C=NC2C(OC)=NC(N)=NC1=2)[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 |&1:12,13,15,17,r|
CAS DataBase Reference :121032-29-9(CAS DataBase Reference)
alpha :D20 +55.9° (c = 0.27 in DMF)
Boiling point :721.0±70.0 °C(Predicted)
Density :1.98±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly, Sonicated)
form :Solid
pka :13.07±0.70(Predicted)
color :White
Water Solubility :H2O: 5mg/mL, clear (warmed)
InChI :InChI=1/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10-/s3
InChIKey :IXOXBSCIXZEQEQ-GCTRTDOSNA-N
SMILES :N1(C=NC2C(OC)=NC(N)=NC1=2)[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 |&1:12,13,15,17,r|
CAS DataBase Reference :121032-29-9(CAS DataBase Reference)
Safety Information
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Description
Nelarabine is a new member of the purine nucleoside antimetabolite class of drugs. It was launched as an intravenous infusion for treating relapsed or refractory T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) after at least two prior chemotherapy regimens. Nelarabine is a pro-drug of 9-b-D-arabinofuranosylguanine (ara-G), a deoxyguanosine derivative with a high level of T-cell selective cytotoxicity. Although Ara-G has been known since the 1960s, it has not been used in clinical studies due to its poor solubility. Nelarabine is the O-methyl derivative of ara-G with approximately 10 times greater aqueous solubility. It is demethylated in vivo by adenosine deaminase to produce ara-G, which is subsequently converted to the active 5’-triphosphate, ara-GTP. Accumulation of ara-GTP in leukemic blasts allows for incorporation into DNA, leading to inhibition of DNA synthesis and cell death.Related product price
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Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
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