Neoandrographolide
|
- $35 - $2395.3
- Product name: Neoandrographolide
- CAS: 27215-14-1
- MF: C26H40O8
- MW: 480.59
- EINECS:
- MDL Number:MFCD07779130
- Synonyms:3-[2-[(4as,5r,8as)-5,8a-dimethyl-2-methylidene-5-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1h-naphthalen-1-yl]ethyl]-5h-furan-2-one;ANDROGRAPHOLIDE, NEO-;NEOANDROGRAPHOLIDE;2(5H)-Furanone, 3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-;3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-Glucopyranosyloxy)methyl]-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,8a-dimethyl-2-methylenenaphthalene-1-yl]ethyl]-2(5H)-furanone;3-[2-[(1R,4aβ)-5α-[(β-D-Glucopyranosyloxy)methyl]decahydro-5,8aα-dimethyl-2-methylenenaphthalen-1α-yl]ethyl]furan-2(5H)-one;4-[2-[(4aS,5R,8aS)-5,8a-dimethyl-2-methylene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxymethyl]decalin-1-yl]ethyl]-2H-furan-5-one;4-[2-[(4aS,5R,8aS)-5,8a-dimethyl-2-methylidene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-2H-furan-5-one
42 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- DC Chemicals
- JR MediChem
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 1MG
- 2mg
- 5mg
- 10mg
- 20mg
- 25mg
- 100mg
- 250mg
- 1g
- 10 mg
- ManufacturerAK Scientific
- Product number8182AH
- Product descriptionNeoandrographolide
- Packaging5mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8182AH
- Product descriptionNeoandrographolide
- Packaging10mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8182AH
- Product descriptionNeoandrographolide
- Packaging25mg
- Price$334
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA240618
- Product descriptionNeoandrographolide 98+%
- Packaging5mg
- Price$81
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA240618
- Product descriptionNeoandrographolide 98+%
- Packaging10mg
- Price$118
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0000574
- Product descriptionNEOANDROGRA-PHOLIDE 95.00%
- Packaging1MG
- Price$148.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0000574
- Product descriptionNEOANDROGRA-PHOLIDE 95.00%
- Packaging5MG
- Price$502.6
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging1mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging2mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging5mg
- Price$64
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN97766
- Product descriptionNeoandrographolide ≥98%
- Packaging20mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY009415
- Product description3-[2-[(1R,4aS,5R,8aS)-5-[(beta-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone
- Packaging10mg
- Price$171.82
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS030100
- Product descriptionNeoandrographolide ≥98%
- Packaging25mg
- Price$221
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1813
- Product descriptionNeoandrographolide
- Packaging10mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594140
- Product descriptionNeoandrographolide
- Packaging20mg
- Price$375.7
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8182AH | Neoandrographolide | 5mg | $134 | 2021-12-16 | Buy |
| AK Scientific | 8182AH | Neoandrographolide | 10mg | $178 | 2021-12-16 | Buy |
| AK Scientific | 8182AH | Neoandrographolide | 25mg | $334 | 2021-12-16 | Buy |
| Ambeed | A240618 | Neoandrographolide 98+% | 5mg | $81 | 2021-12-16 | Buy |
| Ambeed | A240618 | Neoandrographolide 98+% | 10mg | $118 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0000574 | NEOANDROGRA-PHOLIDE 95.00% | 1MG | $148.05 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0000574 | NEOANDROGRA-PHOLIDE 95.00% | 5MG | $502.6 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 1mg | $35 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 2mg | $51 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 5mg | $64 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 10mg | $99 | 2021-12-16 | Buy |
| Arctom | CFN97766 | Neoandrographolide ≥98% | 20mg | $128 | 2021-12-16 | Buy |
| Arctom | SY009415 | 3-[2-[(1R,4aS,5R,8aS)-5-[(beta-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone | 10mg | $171.82 | 2021-12-16 | Buy |
| Arctom | AS030100 | Neoandrographolide ≥98% | 25mg | $221 | 2021-12-16 | Buy |
| AvaChem | 1813 | Neoandrographolide | 10mg | $239 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594140 | Neoandrographolide | 20mg | $375.7 | 2021-12-16 | Buy |
Properties
Melting point :167～168℃
Boiling point :668.1±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.93±0.70(Predicted)
form :Solid
color :White
InChIKey :YGCYRQKJYWQXHG-ACIHAPLFNA-N
SMILES :[C@@]12(C)CCC[C@@](C)(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@]1([H])CCC(=C)[C@H]2CCC1=CCOC1=O |&1:0,5,9,11,14,16,18,20,26,r|
Boiling point :668.1±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.93±0.70(Predicted)
form :Solid
color :White
InChIKey :YGCYRQKJYWQXHG-ACIHAPLFNA-N
SMILES :[C@@]12(C)CCC[C@@](C)(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@]1([H])CCC(=C)[C@H]2CCC1=CCOC1=O |&1:0,5,9,11,14,16,18,20,26,r|
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Neoandrographolide is one of the principle diterpenoids isolated from A. paniculata, a well-recognized medicinal plant in Asia. Extracts from A. paniculata have been reported to exert a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, anti-viral, anti-bacterial, anti-diabetic, anti-oxidative stress, antipyretic, anti-edematogenic, and anti-nociceptive activities. Neoandrographolide has been shown to inhibit LPS-induced nitric oxide production in inflammatory macrophages after oral administration to mice (25 mg/kg) or by direct addition to cultured macrophages (IC50 = 35.5 μM). At 25 μM, it can reduce VEGF-induced proliferation of human umbilical vein endothelial cells. Neoandrographolide also inhibits the pro-protein convertase furin with an IC50 value of 53.5 μM.Related product price
- Andrographolide
$10-640 - N,N-Dimethylformamide
$11.2-12200 - Dimethyl ether
$75-649
