ON-01910
|
- $11 - $2500
- Product name: ON-01910
- CAS: 1225497-78-8
- MF: C21H26NNaO8S
- MW: 475.49
- EINECS:-0
- MDL Number:MFCD11655911
- Synonyms:ON-01910;Estybon;N-[2-Methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine sodium salt;ON 01910 sodium salt;ON-01910;ESTYBON;Rigosertib (ON-01910);N-[2-methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-glycine,sodium salt (1:1);N-[2-Methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine sodium salt Rigosertib (ON-01910)
41 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 5mg
- 10mM*1mLinDMSO
- 1mg
- 10mg
- 25mg
- 50mg
- 100mg
- 10mM(in1mLDMSO)
- 1g
- 10mM(in 1mL DMSO)
- 250MG
- Manufactureraablocks
- Product numberAA0017DA
- Product descriptionRigosertib Sodium(Random Configuration) ≥98%
- Packaging5mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0017DA
- Product descriptionRigosertib Sodium(Random Configuration) ≥98%
- Packaging10mg
- Price$20
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0017DA
- Product descriptionRigosertib Sodium(Random Configuration) 98%（E）
- Packaging25mg
- Price$37
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0017DA
- Product descriptionRigosertib Sodium(Random Configuration) 98%（E）
- Packaging50mg
- Price$58
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0017DA
- Product descriptionRigosertib Sodium(Random Configuration) ≥98%
- Packaging100mg
- Price$105
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX217359
- Product descriptionRigosertib (ON-01910) 98%
- Packaging100MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX217359
- Product descriptionRigosertib (ON-01910) 98%
- Packaging250MG
- Price$220
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX7376
- Product descriptionSodium{[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate
- Packaging25mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000600
- Product descriptionON-01910 95.00%
- Packaging5MG
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1404
- Product descriptionRigosertib sodium salt
- Packaging25mg
- Price$349
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1404
- Product descriptionRigosertib sodium salt
- Packaging100mg
- Price$880
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1404
- Product descriptionRigosertibsodiumsalt
- Packaging10mM(in 1mL DMSO)
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1404
- Product descriptionRigosertib sodium salt
- Packaging10mM(in1mLDMSO)
- Price$121
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1404
- Product descriptionRigosertib sodium salt
- Packaging5mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberCFN60271
- Product descriptionRigosertib(ON-01910) ≥98%
- Packaging10mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181113
- Product descriptionRigosertib
- Packaging250mg
- Price$1260
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0017DA | Rigosertib Sodium(Random Configuration) ≥98% | 5mg | $11 | 2026-05-28 | Buy |
| aablocks | AA0017DA | Rigosertib Sodium(Random Configuration) ≥98% | 10mg | $20 | 2026-05-28 | Buy |
| aablocks | AA0017DA | Rigosertib Sodium(Random Configuration) 98%（E） | 25mg | $37 | 2026-05-28 | Buy |
| aablocks | AA0017DA | Rigosertib Sodium(Random Configuration) 98%（E） | 50mg | $58 | 2026-05-28 | Buy |
| aablocks | AA0017DA | Rigosertib Sodium(Random Configuration) ≥98% | 100mg | $105 | 2026-05-28 | Buy |
| ACHEMBLOCK | X217359 | Rigosertib (ON-01910) 98% | 100MG | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | X217359 | Rigosertib (ON-01910) 98% | 250MG | $220 | 2026-05-27 | Buy |
| AK Scientific | X7376 | Sodium{[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate | 25mg | $420 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000600 | ON-01910 95.00% | 5MG | $330 | 2021-12-16 | Buy |
| ApexBio Technology | A1404 | Rigosertib sodium salt | 25mg | $349 | 2026-05-06 | Buy |
| ApexBio Technology | A1404 | Rigosertib sodium salt | 100mg | $880 | 2026-05-06 | Buy |
| ApexBio Technology | A1404 | Rigosertibsodiumsalt | 10mM(in 1mL DMSO) | $220 | 2021-12-16 | Buy |
| ApexBio Technology | A1404 | Rigosertib sodium salt | 10mM(in1mLDMSO) | $121 | 2026-05-06 | Buy |
| ApexBio Technology | A1404 | Rigosertib sodium salt | 5mg | $110 | 2026-05-06 | Buy |
| Arctom | CFN60271 | Rigosertib(ON-01910) ≥98% | 10mg | $238 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181113 | Rigosertib | 250mg | $1260 | 2026-05-06 | Buy |
Properties
Melting point :>256oC (dec.)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :Pale Yellow to Pale Green
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :Pale Yellow to Pale Green
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
ON-01910 is a potent, non-ATP-competitive inhibitor of polo-like kinase 1 (Plk1; IC50 = 9 nM), a serine/threonine protein kinase involved in the regulation of cell cycling. It induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM) and blocks the growth of multidrug resistant cancer cell lines. ON-01910 is active in vivo when administered intraperitoneally and synergizes with chemotherapeutic agents, preventing tumor growth or abolishing tumors in human xenograft nude mouse models.Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
Chembest Research Laboratories Limited
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Shanghai Hanhong Scientific Co.,Ltd.
Jinan Trio PharmaTech Co., Ltd.
China Langchem Inc.
Dalian Meilun Biotech Co., Ltd.
Shanghai civi chemical technology co.,Ltd
NCE Biomedical Co.,Ltd.
shanghai cooperpharm co.,LTD .