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ChemicalBook >> CAS DataBase List >> PDDHV

PDDHV

PDDHV price.
  • $63 - $191
  • Product name: PDDHV
  • CAS: 179469-40-0
  • MF: C49H72O11
  • MW: 837.09
  • EINECS:
  • MDL Number:MFCD02684413
  • Synonyms:PHORBOL 12,13-DIDECANOATE 20-HOMOVANILLATE;PDDHV;Benzeneacetic acid, 4-hydroxy-3-methoxy-, [(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9,9a-bis[(1-oxodecyl)oxy]-1H-cyclopropa[3,4]benz[1,2-e]azulen-3-yl]methyl ester
4 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number9070CR
  • Product descriptionPddhv
  • Packaging1mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008544
  • Product descriptionPHORBOL 12,13-DIDECANOATE 20-HOMOVANILLATE 95.00%
  • Packaging1MG
  • Price$151.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20445
  • Product descriptionPDDHV ≥99%
  • Packaging1mg
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20445
  • Product descriptionPDDHV ≥99%
  • Packaging5mg
  • Price$191
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9070CR Pddhv 1mg $160 2021-12-16 Buy
American Custom Chemicals Corporation API0008544 PHORBOL 12,13-DIDECANOATE 20-HOMOVANILLATE 95.00% 1MG $151.2 2021-12-16 Buy
Cayman Chemical 20445 PDDHV ≥99% 1mg $63 2024-03-01 Buy
Cayman Chemical 20445 PDDHV ≥99% 5mg $191 2021-12-16 Buy

Properties

storage temp. :−20°C
solubility :Methanol: soluble
form :A solid

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PDDHV is a resiniferatoxin (RTX)-type phorboid vanilloid with capsaicin-like selectivity for VR1, shown to evoke Ca2+ uptake in rat dorsal root ganglion neurons with an EC50 = 70nM, while inhibiting RTX binding to said neurons with a much lower potency (Ki > 10,000 nM). The ability of PDDHV to elicit Ca2+ uptake at sub-micromolar concentrations, while having a much lower binding affinity to rat dorsal root ganglion membranes, represents more than 100 times capsaicin-like pharmacology. PDDHV provides a tool to explore this capsaicin-like, vanilloid pharmacology.

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