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ChemicalBook >> CAS DataBase List >> PF 4800567 hydrochloride

PF 4800567 hydrochloride

$37 - $2085
Product name: PF 4800567 hydrochloride
CAS: 1188296-52-7
MF: C17H18ClN5O2
MW: 359.81
EINECS:
MDL Number:MFCD22123245
Synonyms:3-[(3-Chlorophenoxy)Methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine Hydrochloride;PF 4800567;3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;PF 4800567 hydrochloride;3-[(3-chlorophenoxy)methyl]-1-(oxan-4-yl)pyrazolo[3,4-d]pyrimidin-4-amine;PF 4800567;PF-4800567;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-;Casein Kinase,PF4800567,inhibit,PF-4800567,PF 4800567,Inhibitor

Price20 Properties Safety Information Description

20 prices

Selected condition：

Brand

AK Scientific
Ambeed
American Custom Chemicals Corporation
Axon Medchem
Cayman Chemical
Chemenu
ChemScene
DC Chemicals
Sigma-Aldrich
Tocris

Package

5mg
25mg
10
1mg
10mg
50MG
2x25mg
100mg
1g
5g
5 mg

ManufacturerAK Scientific
Product number3434DL
Product description3-[(3-Chlorophenoxy)methyl]-1-(Tetrahydro-2h-Pyran-4-Yl)-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine
Packaging5mg
Price$256
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA558311
Product descriptionPF-4800567 99%
Packaging5mg
Price$73
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA558311
Product descriptionPF-4800567 99%
Packaging10mg
Price$143
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010274
Product description3-[(3-CHLOROPHENOXY)METHYL]-1-(TETRAHYDRO-2H-PYRAN-4-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE HYDROCHLORIDE 95.00%
Packaging10MG
Price$315
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010274
Product description3-[(3-CHLOROPHENOXY)METHYL]-1-(TETRAHYDRO-2H-PYRAN-4-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE HYDROCHLORIDE 95.00%
Packaging50MG
Price$1437.11
Updated2021-12-16
Buy

ManufacturerAxon Medchem
Product numberAxon1792
Product descriptionPF4800567 98%
Packaging2x25mg
Price$572
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number19171
Product descriptionPF-4800567 ≥98%
Packaging1mg
Price$37
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number19171
Product descriptionPF-4800567 ≥98%
Packaging5mg
Price$142
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number19171
Product descriptionPF-4800567 ≥98%
Packaging10mg
Price$231
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number19171
Product descriptionPF-4800567 ≥98%
Packaging25mg
Price$530
Updated2024-03-01
Buy

ManufacturerChemenu
Product numberCM151843
Product description3-((3-chlorophenoxy)methyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 97%
Packaging1g
Price$791
Updated2021-12-16
Buy

ManufacturerChemenu
Product numberCM151843
Product description3-((3-chlorophenoxy)methyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 97%
Packaging5g
Price$2085
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-0011718
Product descriptionPF-4800567 98.38%
Packaging5mg
Price$80
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-0011718
Product descriptionPF-4800567 98.38%
Packaging10mg
Price$140
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-0011718
Product descriptionPF-4800567 98.38%
Packaging25mg
Price$290
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-0011718
Product descriptionPF-4800567 98.38%
Packaging50mg
Price$490
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	3434DL	3-[(3-Chlorophenoxy)methyl]-1-(Tetrahydro-2h-Pyran-4-Yl)-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine	5mg	$256	2021-12-16	Buy
Ambeed	A558311	PF-4800567 99%	5mg	$73	2021-12-16	Buy
Ambeed	A558311	PF-4800567 99%	10mg	$143	2021-12-16	Buy
American Custom Chemicals Corporation	API0010274	3-[(3-CHLOROPHENOXY)METHYL]-1-(TETRAHYDRO-2H-PYRAN-4-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE HYDROCHLORIDE 95.00%	10MG	$315	2021-12-16	Buy
American Custom Chemicals Corporation	API0010274	3-[(3-CHLOROPHENOXY)METHYL]-1-(TETRAHYDRO-2H-PYRAN-4-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE HYDROCHLORIDE 95.00%	50MG	$1437.11	2021-12-16	Buy
Axon Medchem	Axon1792	PF4800567 98%	2x25mg	$572	2021-12-16	Buy
Cayman Chemical	19171	PF-4800567 ≥98%	1mg	$37	2024-03-01	Buy
Cayman Chemical	19171	PF-4800567 ≥98%	5mg	$142	2024-03-01	Buy
Cayman Chemical	19171	PF-4800567 ≥98%	10mg	$231	2024-03-01	Buy
Cayman Chemical	19171	PF-4800567 ≥98%	25mg	$530	2024-03-01	Buy
Chemenu	CM151843	3-((3-chlorophenoxy)methyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 97%	1g	$791	2021-12-16	Buy
Chemenu	CM151843	3-((3-chlorophenoxy)methyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 97%	5g	$2085	2021-12-16	Buy
ChemScene	CS-0011718	PF-4800567 98.38%	5mg	$80	2021-12-16	Buy
ChemScene	CS-0011718	PF-4800567 98.38%	10mg	$140	2021-12-16	Buy
ChemScene	CS-0011718	PF-4800567 98.38%	25mg	$290	2021-12-16	Buy
ChemScene	CS-0011718	PF-4800567 98.38%	50mg	$490	2021-12-16	Buy

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Properties

Boiling point :592.9±50.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :4.01±0.30(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ. It blocks CK1ε-mediated PER3 nuclear localization and PER2 degradation, both of which are proteins important for maintaining circadian rhythms in cells. PF-4800567 has been used in the study of the CK1 enzymes in the regulation of circadian rhythm and is also reported to have neuroprotective effects.

Suppliers and manufacturers

TargetMol Chemicals Inc.

$38.00 /5mg
PF-4800567 CAS:1188296-52-7

ATK CHEMICAL COMPANY LIMITED

Career Henan Chemica Co

InvivoChem

TargetMol Chemicals Inc.

Wuhan Topule Biopharmaceutical Co., Ltd

Aladdin Scientific Shanghai Boyle Chemical Co., Ltd. Chemsky (shanghai) International Co.,Ltd Guangzhou Zhiya Chemdrugs Co.,Ltd

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