PF-562271
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- $16 - $2541.5
- Product name: PF-562271
- CAS: 939791-38-5
- MF: C27H26F3N7O6S2
- MW: 665.66
- EINECS:-0
- MDL Number:MFCD14105612
- Synonyms:PF-562271 PhSO3H salt;PF-562271 benzenesulfonate salt;PF-00562271 (PF-562271);N-[3-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide benzenesulfonate;PF-562271 (besylate);N-methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide benzenesulfonate;PF-00562271, >=98%;PF-562271 benzenesulfonate
53 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 1g
- 10mM*1mLinDMSO(Solution)
- 10mM(in 1mL DMSO)
- 25mg
- 500ug
- 1mg
- 25 mg
- 10mM*1mLinDMSO
- 5 mg
- 10mM(in1mLDMSO)
- 250ug
- 1unit
- 2mg
- 5mg
- 10mg
- 50mg
- 100mg
- 200mg
- 250MG
- EvaluationSample
- Manufactureraablocks
- Product numberAA00GU2O
- Product descriptionPF-562271 besylate 98%
- Packaging1mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU2O
- Product descriptionPF-562271 besylate 98%
- Packaging2mg
- Price$20
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU2O
- Product descriptionPF-562271 besylate 98%
- Packaging5mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU2O
- Product descriptionPF-562271 besylate 98%
- Packaging10mg
- Price$46
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU2O
- Product descriptionPF-562271 besylate 98
- Packaging50mg
- Price$197
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU2O
- Product descriptionPF-562271 besylate 98
- Packaging100mg
- Price$284
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU2O
- Product descriptionPF-562271 besylate 98
- Packaging200mg
- Price$400
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8175
- Product descriptionN-Methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide benzenesulfonate 95%
- Packaging100MG
- Price$300
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8175
- Product descriptionN-Methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide benzenesulfonate 95%
- Packaging250MG
- Price$510
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0329
- Product descriptionN-methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamidebenzenesulfonate
- Packaging50mg
- Price$961
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0014065
- Product descriptionPF-562271 BENZENE SULPHONATE 95.00%
- Packaging5MG
- Price$459.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8320
- Product descriptionPF-00562271
- Packaging5mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8320
- Product descriptionPF-00562271
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8320
- Product descriptionPF-00562271
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8320
- Product descriptionPF-00562271
- Packaging10mM(in1mLDMSO)
- Price$66
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8320
- Product descriptionPF-00562271
- Packaging10mM(in 1mL DMSO)
- Price$105
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GU2O | PF-562271 besylate 98% | 1mg | $16 | 2026-05-28 | Buy |
| aablocks | AA00GU2O | PF-562271 besylate 98% | 2mg | $20 | 2026-05-28 | Buy |
| aablocks | AA00GU2O | PF-562271 besylate 98% | 5mg | $32 | 2026-05-28 | Buy |
| aablocks | AA00GU2O | PF-562271 besylate 98% | 10mg | $46 | 2026-05-28 | Buy |
| aablocks | AA00GU2O | PF-562271 besylate 98 | 50mg | $197 | 2026-05-28 | Buy |
| aablocks | AA00GU2O | PF-562271 besylate 98 | 100mg | $284 | 2026-05-28 | Buy |
| aablocks | AA00GU2O | PF-562271 besylate 98 | 200mg | $400 | 2026-05-28 | Buy |
| ACHEMBLOCK | H-8175 | N-Methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide benzenesulfonate 95% | 100MG | $300 | 2026-05-27 | Buy |
| ACHEMBLOCK | H-8175 | N-Methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide benzenesulfonate 95% | 250MG | $510 | 2026-05-27 | Buy |
| AK Scientific | Y0329 | N-methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamidebenzenesulfonate | 50mg | $961 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0014065 | PF-562271 BENZENE SULPHONATE 95.00% | 5MG | $459.8 | 2021-12-16 | Buy |
| ApexBio Technology | A8320 | PF-00562271 | 5mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | A8320 | PF-00562271 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8320 | PF-00562271 | EvaluationSample | $30 | 2026-05-06 | Buy |
| ApexBio Technology | A8320 | PF-00562271 | 10mM(in1mLDMSO) | $66 | 2026-05-06 | Buy |
| ApexBio Technology | A8320 | PF-00562271 | 10mM(in 1mL DMSO) | $105 | 2021-12-16 | Buy |
Properties
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :insoluble in EtOH; insoluble in H2O; ≥11.1 mg/mL in DMSO with gentle warming
form :solid
color :Off-white to light yellow
InChIKey :LKLWTLXTOVZFAE-UHFFFAOYSA-N
SMILES :S(C1C=CC=CC=1)(O)(=O)=O.O=C1CC2=CC(NC3=NC=C(C(F)(F)F)C(NCC4C=CC=NC=4N(C)S(=O)(=O)C)=N3)=CC=C2N1
solubility :insoluble in EtOH; insoluble in H2O; ≥11.1 mg/mL in DMSO with gentle warming
form :solid
color :Off-white to light yellow
InChIKey :LKLWTLXTOVZFAE-UHFFFAOYSA-N
SMILES :S(C1C=CC=CC=1)(O)(=O)=O.O=C1CC2=CC(NC3=NC=C(C(F)(F)F)C(NCC4C=CC=NC=4N(C)S(=O)(=O)C)=N3)=CC=C2N1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) are non-receptor tyrosine kinases that constitute the FAK subfamily and play a vital role in many oncogenic pathways. PF-562271 is an ATP-competitive, reversible inhibitor of FAK (IC50 = 1.5 nM) that demonstrates 10-fold reduced potency for PYK2 (IC50 = 14 nM) and >100-fold selectivity against other protein kinases. PF-562271 inhibits FAK phosphorylation with an EC50 value of 93 ng/ml in glioblastoma-bearing mice and has been shown to regress tumors in multiple xenograft models.More related product prices
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