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ChemicalBook >> CAS DataBase List >> PF429242 dihydrochloride

PF429242 dihydrochloride

PF429242 dihydrochloride price.
  • $50 - $1056
  • Product name: PF429242 dihydrochloride
  • CAS: 2248666-66-0
  • MF: C25H36ClN3O2
  • MW: 446.03
  • EINECS:
  • MDL Number:
  • Synonyms:PF 429242-HCl;PF429242,PF-429242 dihydrochloride,PF429242 dihydrochloride,Virus Protease,inhibit,PF 429242,Inhibitor,Fatty Acid Synthase (FASN),PF-429242;PF429242 2HCl;PF429242 dihydrochloride, 10 mM in DMSO
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number4497EB
  • Product descriptionPF-429242 dihydrochloride
  • Packaging1mg
  • Price$151
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4497EB
  • Product descriptionPF-429242 dihydrochloride
  • Packaging5mg
  • Price$241
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15140
  • Product descriptionPF-429242 (hydrochloride)
  • Packaging1mg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15140
  • Product descriptionPF-429242 (hydrochloride)
  • Packaging5mg
  • Price$135
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15140
  • Product descriptionPF-429242 (hydrochloride)
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15140
  • Product descriptionPF-429242 (hydrochloride)
  • Packaging25mg
  • Price$547
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6890
  • Product descriptionPF-429242 dihydrochloride 98.08%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6890
  • Product descriptionPF-429242 dihydrochloride 98.08%
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6890
  • Product descriptionPF-429242 dihydrochloride 98.08%
  • Packaging25mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6890
  • Product descriptionPF-429242 dihydrochloride 98.08%
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6890
  • Product descriptionPF-429242 dihydrochloride 98.08%
  • Packaging100mg
  • Price$1056
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4497EB PF-429242 dihydrochloride 1mg $151 2021-12-16 Buy
AK Scientific 4497EB PF-429242 dihydrochloride 5mg $241 2021-12-16 Buy
Cayman Chemical 15140 PF-429242 (hydrochloride) 1mg $50 2024-03-01 Buy
Cayman Chemical 15140 PF-429242 (hydrochloride) 5mg $135 2024-03-01 Buy
Cayman Chemical 15140 PF-429242 (hydrochloride) 10mg $243 2024-03-01 Buy
Cayman Chemical 15140 PF-429242 (hydrochloride) 25mg $547 2024-03-01 Buy
ChemScene CS-6890 PF-429242 dihydrochloride 98.08% 5mg $96 2021-12-16 Buy
ChemScene CS-6890 PF-429242 dihydrochloride 98.08% 10mg $168 2021-12-16 Buy
ChemScene CS-6890 PF-429242 dihydrochloride 98.08% 25mg $336 2021-12-16 Buy
ChemScene CS-6890 PF-429242 dihydrochloride 98.08% 50mg $600 2021-12-16 Buy
ChemScene CS-6890 PF-429242 dihydrochloride 98.08% 100mg $1056 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form :A crystalline solid
color :White to light brown

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

PF-429242 is an inhibitor of site-1 protease with an IC50 value of 170 nM for human recombinant site-1 protease. It is selective for site-1 protease over trypsin, elastase, proteinase K, plasmin, kallikren, factor XIa, thrombin, and furin at concentrations up to 100 μM. PF-429242 completely inhibits proteolytic processing and nuclear translocation of sterol regulatory element-binding protein (SREBP) in HepG2 cells at a concentration of 10 μM. It also reduces expression of HMG-CoA synthase and fatty acid synthase (EC50s = 0.3 and 2 μM, respectively) and inhibits cholesterol synthesis (EC50 = 600 nM) in HepG2 cells and reduces cholesterol and fatty acid synthesis in CD-1 mice. PF-429242 inhibits replication of dengue virus serotypes 1-4 in infected HeLa cells. It also reduces growth of T98G, U87-MG, and A172 glioblastoma cells (IC50s = 0.32, 15.2, and 27.6 μM, respectively).

Suppliers and manufacturers

TargetMol Chemicals Inc.
PF429242 dihydrochloride
$36.00 /1mg
PF429242 dihydrochloride CAS:2248666-66-0
TargetMol Chemicals Inc.
PF429242 dihydrochloride
$36.00 /1mg
PF429242 dihydrochloride CAS:2248666-66-0
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
LEAP CHEM CO., LTD.
Aladdin Scientific Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Beijing Solarbio Science & Tecnology Co., Ltd.