PRIMA-1
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- $19 - $2325
- Product name: PRIMA-1
- CAS: 5608-24-2
- MF: C9H15NO3
- MW: 185.22
- EINECS:
- MDL Number:MFCD19199989
- Synonyms:PRIMA-1;P53 REACTIVATION AND INDUCTION OF MASSIVE APOPTOSIS;2,2-BIS(HYDROXYMETHYL)-1-AZABICYCLO[2,2,2]OCTAN-3-ONE;2,2-BIS(HYDROXYMETHYL)-3-QUINUCLIDINONE;2,2-dimethylolquinuclidin-3-one;7,7-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-8-one;PRIMA-1 - CAS 5608-24-2 - Calbiochem;2-Bis(hydroxymethyl)-3-quinuclidinone
34 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Arctom
- Cayman Chemical
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 10
- 1unit
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 50
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAHH
- Product numberAPI-1964
- Product descriptionPRIMA-1 Prima-1
- Packaging1g
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1997AH
- Product description2,2-Bis(hydroxymethyl)-3-quinuclidinone
- Packaging5mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64071
- Product descriptionPRIMA-1
- Packaging10mg
- Price$219.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging10mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging25mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging50mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging100mg
- Price$224
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA755385
- Product descriptionPRIMA-1 98%
- Packaging1g
- Price$2325
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging5mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4483
- Product descriptionPRIMA-1
- Packaging50mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS658179
- Product descriptionPRIMA-1 98%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number63520
- Product descriptionPRIMA-1 ≥95%
- Packaging1mg
- Price$19
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | API-1964 | PRIMA-1 Prima-1 | 1g | $1200 | 2021-12-16 | Buy |
| AK Scientific | 1997AH | 2,2-Bis(hydroxymethyl)-3-quinuclidinone | 5mg | $124 | 2021-12-16 | Buy |
| Alfa Aesar | J64071 | PRIMA-1 | 10mg | $219.65 | 2024-03-01 | Buy |
| Ambeed | A755385 | PRIMA-1 98% | 5mg | $51 | 2021-12-16 | Buy |
| Ambeed | A755385 | PRIMA-1 98% | 10mg | $77 | 2021-12-16 | Buy |
| Ambeed | A755385 | PRIMA-1 98% | 25mg | $134 | 2021-12-16 | Buy |
| Ambeed | A755385 | PRIMA-1 98% | 50mg | $173 | 2021-12-16 | Buy |
| Ambeed | A755385 | PRIMA-1 98% | 100mg | $224 | 2021-12-16 | Buy |
| Ambeed | A755385 | PRIMA-1 98% | 1g | $2325 | 2021-12-16 | Buy |
| ApexBio Technology | A4483 | PRIMA-1 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A4483 | PRIMA-1 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4483 | PRIMA-1 | 5mg | $56 | 2021-12-16 | Buy |
| ApexBio Technology | A4483 | PRIMA-1 | 10mg | $75 | 2021-12-16 | Buy |
| ApexBio Technology | A4483 | PRIMA-1 | 50mg | $245 | 2021-12-16 | Buy |
| Arctom | AS658179 | PRIMA-1 98% | 5mg | $50 | 2021-12-16 | Buy |
| Cayman Chemical | 63520 | PRIMA-1 ≥95% | 1mg | $19 | 2024-03-01 | Buy |
Properties
Melting point :146-147 °C
Boiling point :353.7±17.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >10mg/mL
pka :13.68±0.10(Predicted)
form :solid
color :white to off-white
Water Solubility :Soluble in water at 10mg/ml
Sensitive :Light Sensitive
Boiling point :353.7±17.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >10mg/mL
pka :13.68±0.10(Predicted)
form :solid
color :white to off-white
Water Solubility :Soluble in water at 10mg/ml
Sensitive :Light Sensitive
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high μM to mM concentrations. It is therefore a unique anti-oncogenic substance, working as a re-activator of the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1 represents a novel lead compound which may be further modified to provide more potent therapeutic agents acting via the reactivation mechanism.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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