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ChemicalBook >> CAS DataBase List >> Pazopanib

Pazopanib

Pazopanib price.
  • $8 - $1871.1
  • Product name: Pazopanib
  • CAS: 444731-52-6
  • MF: C21H23N7O2S
  • MW: 437.52
  • EINECS:251-228-4
  • MDL Number:MFCD11616589
  • Synonyms:Pazopanib for research;Pazopanib;Pazopanib(GW786034);5-(4-((2,3-diMethyl-3,3a-dihydro-2H-indazol-6-yl)(Methyl)aMino)pyriMidin-2-ylaMino)-2-MethylbenzenesulfonaMide;5-[(4-{[(2,3-diMethyl-2H-indazol-6-yl)Methyl]aMino}pyriMidin-2-yl)aMino]-2-Methylbenzene-1-sulfonaMide;5-({4-[(2,3-diMethyl-2H-indazol-6-yl)(Methyl)aMino]pyriMidin-2-yl}aMino)-2-MethylbenzenesulfonaMide 5-(4-(N-(2,3-diMethyl-2H-indazole-6-yl)- N-MethylaMino)pyriMidine-2-ylaMino)-2-MethylbenzenesulfonaMide;GW786034; VOTRIENT;BenzenesulfonaMide, 5-[[4-[(2,3-diMethyl-2H-indazol-6-yl)MethylaMino]-2-pyriMidinyl]aMino]-2-Methyl-
Price116 Properties Safety Information Description
116 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Chemtos
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 10mM(in1mLDMSO)
  • 5mg
  • 20mg
  • 0.1g
  • 200mg
  • 0.25g
  • 0.5g
  • 1.00g
  • 2g
  • 5.00g
  • 10mM(1mLinDMSO)
  • 25.00g
  • 10mM(in 1mL DMSO)
  • 1mg
  • EvaluationSample
  • 1unit
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 25g
  • Manufactureraablocks
  • Product numberAA00DE2I
  • Product description5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99%
  • Packaging1mg
  • Price$8
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DE2I
  • Product description5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide ≥99%
  • Packaging25mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DE2I
  • Product description5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99%
  • Packaging50mg
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DE2I
  • Product description5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide ≥99%
  • Packaging100mg
  • Price$14
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DE2I
  • Product description5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99%
  • Packaging250mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DE2I
  • Product description5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99%
  • Packaging1g
  • Price$47
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DE2I
  • Product description5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99%
  • Packaging5g
  • Price$136
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DE2I
  • Product description5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 98%
  • Packaging25g
  • Price$540
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT101432
  • Product description5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide 98%
  • Packaging25G
  • Price$590
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT101432
  • Product description5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide 98%
  • Packaging25G
  • Price$590
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT101432
  • Product description5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide 98%
  • Packaging5G
  • Price$215
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT101432
  • Product description5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide 98%
  • Packaging5G
  • Price$215
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3746-M250
  • Product descriptionPazopanib (free base) ≥98%(HPLC)
  • Packaging250mg
  • Price$220
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3746-M050
  • Product descriptionPazopanib (free base) ≥98%(HPLC)
  • Packaging50mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3746-M050
  • Product descriptionPazopanib(freebase) ≥98%(HPLC)
  • Packaging50mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3746-M010
  • Product descriptionPazopanib (free base) ≥98%(HPLC)
  • Packaging10mg
  • Price$25
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00DE2I 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99% 1mg $8 2026-05-28 Buy
aablocks AA00DE2I 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide ≥99% 25mg $10 2026-05-28 Buy
aablocks AA00DE2I 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99% 50mg $12 2026-05-28 Buy
aablocks AA00DE2I 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide ≥99% 100mg $14 2026-05-28 Buy
aablocks AA00DE2I 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99% 250mg $23 2026-05-28 Buy
aablocks AA00DE2I 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99% 1g $47 2026-05-28 Buy
aablocks AA00DE2I 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 99% 5g $136 2026-05-28 Buy
aablocks AA00DE2I 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide 98% 25g $540 2026-05-28 Buy
ACHEMBLOCK T101432 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide 98% 25G $590 2026-05-25 Buy
ACHEMBLOCK T101432 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide 98% 25G $590 2026-05-27 Buy
ACHEMBLOCK T101432 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide 98% 5G $215 2026-05-25 Buy
ACHEMBLOCK T101432 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide 98% 5G $215 2026-05-27 Buy
Adipogen Life Sciences AG-CR1-3746-M250 Pazopanib (free base) ≥98%(HPLC) 250mg $220 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3746-M050 Pazopanib (free base) ≥98%(HPLC) 50mg $90 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3746-M050 Pazopanib(freebase) ≥98%(HPLC) 50mg $75 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3746-M010 Pazopanib (free base) ≥98%(HPLC) 10mg $25 2026-05-06 Buy
Next Last

Properties

Melting point :285-289°C (dec.)
Boiling point :728.8±70.0 °C(Predicted)
Density :1.40
Flash point :359℃
storage temp. :Refrigerator
solubility :Aqueous Acid (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka :10.19±0.60(Predicted)
form :Yellow powder.
color :White to Beige
InChI :InChI=1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
InChIKey :CUIHSIWYWATEQL-UHFFFAOYSA-N
SMILES :CC1N(N=C2C=C(N(C3C=CN=C(NC4C=CC(C)=C(S(=O)(=O)N)C=4)N=3)C)C=CC=12)C

Safety Information

Symbol(GHS): Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment

Description

Pazopanib is a broad spectrum tyrosine kinase inhibitor that blocks angiogenesis through its actions on VEGF receptors (VEGFRs). It has low nanomolar efficacy against VEGFR1 (FLT1), VEGFR2, VEGFR3 (FLT4), and KIT, as well as receptors for macrophage colony-stimulating factor 1 and platelet-derived growth factor. Pazopanib is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 and, to a lesser extent, CYP1A2 and CYP2C8. It is effective in vivo and is useful in the management of certain types of cancer.

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Suppliers and manufacturers

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