Pimecrolimus
|
- $15 - $4030.95
- Product name: Pimecrolimus
- CAS: 137071-32-0
- MF: C43H68ClNO11
- MW: 810.45
- EINECS:603-999-7
- MDL Number:MFCD00901792
- Synonyms:ASM 981;SDZ-ASM 981;Picrolimus;Pimecrolimus;15,19-Epoxy-3H-pyrido(2,1-C)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 3-((1E)-2-((1R,3R,4S)-4-chloro-3-methoxycyclohexyl)-1-methylethenyl)-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26as)-;15,19-Epoxy-3H-pyrido(2,1-C)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 3-(2-(4-chloro-3-methoxycyclohexyl)-1-methylethenyl)-8-ethyl-, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S-(3R*(E(1S*,3S*,4R*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26ar*))-;Unii-7kyv510875;PiMecroliMus(Elidel, SDZ-ASM-981)
34 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200MG
- 250mg
- 1G
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0598-M010
- Product descriptionPimecrolimus ≥97%(HPLC)
- Packaging10mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0598-M010
- Product descriptionPimecrolimus ≥97%(HPLC)
- Packaging10mg
- Price$26
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0598-M050
- Product descriptionPimecrolimus ≥97%(HPLC)
- Packaging50mg
- Price$105
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberX7261
- Product descriptionPimecrolimus
- Packaging50mg
- Price$153
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA944531
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
- Packaging25mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA944531
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
- Packaging100mg
- Price$177
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA944531
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
- Packaging50mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA944531
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
- Packaging5mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA944531
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
- Packaging10mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA944531
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
- Packaging1mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000595
- Product descriptionPIMECROLIMUS 95.00%
- Packaging10MG
- Price$130.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000595
- Product descriptionPIMECROLIMUS 95.00%
- Packaging1G
- Price$4030.95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1817
- Product description(-)-Pimecrolimus
- Packaging50mg
- Price$120
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1817
- Product description(-)-Pimecrolimus
- Packaging25mg
- Price$75
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1817
- Product description(-)-Pimecrolimus
- Packaging100mg
- Price$190
- Updated2026-05-06
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE27046
- Product descriptionPimecrolimus
- Packaging50mg
- Price$263
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-P0598-M010 | Pimecrolimus ≥97%(HPLC) | 10mg | $24 | 2021-12-16 | Buy |
| Adipogen Life Sciences | CDX-P0598-M010 | Pimecrolimus ≥97%(HPLC) | 10mg | $26 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-P0598-M050 | Pimecrolimus ≥97%(HPLC) | 50mg | $105 | 2026-05-06 | Buy |
| AK Scientific | X7261 | Pimecrolimus | 50mg | $153 | 2021-12-16 | Buy |
| Ambeed | A944531 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+% | 25mg | $77 | 2021-12-16 | Buy |
| Ambeed | A944531 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+% | 100mg | $177 | 2021-12-16 | Buy |
| Ambeed | A944531 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+% | 50mg | $115 | 2021-12-16 | Buy |
| Ambeed | A944531 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+% | 5mg | $35 | 2021-12-16 | Buy |
| Ambeed | A944531 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+% | 10mg | $52 | 2021-12-16 | Buy |
| Ambeed | A944531 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+% | 1mg | $15 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000595 | PIMECROLIMUS 95.00% | 10MG | $130.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000595 | PIMECROLIMUS 95.00% | 1G | $4030.95 | 2021-12-16 | Buy |
| ApexBio Technology | B1817 | (-)-Pimecrolimus | 50mg | $120 | 2026-05-06 | Buy |
| ApexBio Technology | B1817 | (-)-Pimecrolimus | 25mg | $75 | 2026-05-06 | Buy |
| ApexBio Technology | B1817 | (-)-Pimecrolimus | 100mg | $190 | 2026-05-06 | Buy |
| Biosynth Carbosynth | FE27046 | Pimecrolimus | 50mg | $263 | 2021-12-16 | Buy |
Properties
Melting point :135-136 °C
Boiling point :866.1±75.0 °C(Predicted)
Density :1.19
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO (Slightly, Sonicated), Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :9.97±0.70(Predicted)
color :White to Off-White
InChIKey :KASDHRXLYQOAKZ-JXCUAROPNA-N
Boiling point :866.1±75.0 °C(Predicted)
Density :1.19
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO (Slightly, Sonicated), Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :9.97±0.70(Predicted)
color :White to Off-White
InChIKey :KASDHRXLYQOAKZ-JXCUAROPNA-N
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase). Presumably through these actions, it blocks the activation of T cells by allogeneic dendritic cells (IC50 = 0.55 nM) without affecting dendritic cells. Moreover, pimecrolimus suppresses the generation of pro-inflammatory cytokines by T cells, the release of pre-formed inflammatory mediators from mast cells, and the activation of eosinophils. These effects support the use of pimecrolimus in countering inflammatory skin diseases, such as atopic dermatitis (eczema) and psoriasis.Related product price
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Suppliers and manufacturers
ENBRIDGE PHARMTECH CO., LTD.
Henan Tianfu Chemical Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Shanghai Arbor Chemical Co., Ltd.




