Pimodivir
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- $45 - $2700
- Product name: Pimodivir
- CAS: 1629869-44-8
- MF: C20H19F2N5O2
- MW: 399.39
- EINECS:
- MDL Number:MFCD31382121
- Synonyms:Pimodivir;Pimodivir (VX-787);VRT0928787;VRT-0928787;VX-787; VX 787; VX787; JNJ-872; JNJ 872; JNJ872; VRT-0928787; VRT 0928787; VRT0928787;PIMODIVIR;VX-787 (Pimodivir);Bicyclo[2.2.2]octane-2-carboxylic acid, 3-[[5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]-, (2S,3S)-;(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
39 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AHH
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mL(10mMinDMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA01EN1K
- Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
- Packaging1mg
- Price$45
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EN1K
- Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
- Packaging5mg
- Price$78
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EN1K
- Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
- Packaging10mg
- Price$118
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EN1K
- Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
- Packaging25mg
- Price$199
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EN1K
- Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
- Packaging50mg
- Price$286
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EN1K
- Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
- Packaging100mg
- Price$420
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228290
- Product descriptionPimodivir 97.00%
- Packaging100MG
- Price$595
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228290
- Product descriptionPimodivir 97.00%
- Packaging25MG
- Price$265
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberAPI-1946
- Product descriptionVX787 97%
- Packaging1g
- Price$2300
- Updated2026-05-26
- Buy
- ManufacturerApexBio Technology
- Product numberBA2005
- Product descriptionPimodivir
- Packaging100mg
- Price$792
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2005
- Product descriptionPimodivir
- Packaging1mL(10mMinDMSO)
- Price$89
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2005
- Product descriptionPimodivir
- Packaging5mg
- Price$81
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2005
- Product descriptionPimodivir
- Packaging50mg
- Price$459
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA2005
- Product descriptionPimodivir
- Packaging10mg
- Price$135
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-12353A
- Product descriptionPimodivir 99.40%
- Packaging10mg
- Price$143
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12353A
- Product descriptionPimodivir 99.40%
- Packaging5mg
- Price$86
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EN1K | (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid | 1mg | $45 | 2026-05-30 | Buy |
| aablocks | AA01EN1K | (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid | 5mg | $78 | 2026-05-30 | Buy |
| aablocks | AA01EN1K | (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid | 10mg | $118 | 2026-05-30 | Buy |
| aablocks | AA01EN1K | (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid | 25mg | $199 | 2026-05-30 | Buy |
| aablocks | AA01EN1K | (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid | 50mg | $286 | 2026-05-30 | Buy |
| aablocks | AA01EN1K | (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid | 100mg | $420 | 2026-05-30 | Buy |
| ACHEMBLOCK | Y228290 | Pimodivir 97.00% | 100MG | $595 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228290 | Pimodivir 97.00% | 25MG | $265 | 2026-05-27 | Buy |
| AHH | API-1946 | VX787 97% | 1g | $2300 | 2026-05-26 | Buy |
| ApexBio Technology | BA2005 | Pimodivir | 100mg | $792 | 2026-05-06 | Buy |
| ApexBio Technology | BA2005 | Pimodivir | 1mL(10mMinDMSO) | $89 | 2026-05-06 | Buy |
| ApexBio Technology | BA2005 | Pimodivir | 5mg | $81 | 2026-05-06 | Buy |
| ApexBio Technology | BA2005 | Pimodivir | 50mg | $459 | 2026-05-06 | Buy |
| ApexBio Technology | BA2005 | Pimodivir | 10mg | $135 | 2026-05-06 | Buy |
| Arctom | HY-12353A | Pimodivir 99.40% | 10mg | $143 | 2026-05-26 | Buy |
| Arctom | HY-12353A | Pimodivir 99.40% | 5mg | $86 | 2026-05-26 | Buy |
Properties
Density :1.501±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO, not in water:100.0(Max Conc. mg/mL);250.38(Max Conc. mM)
form :A solid
pka :4.32±0.40(Predicted)
color :White to light yellow
InChIKey :JGPXDNKSIXAZEQ-SBBZOCNPSA-N
SMILES :C12CCC(CC1)[C@H](NC1C(F)=CN=C(C3C4=CC(F)=CN=C4NC=3)N=1)[C@H]2C(O)=O
storage temp. :Store at -20°C
solubility :Soluble in DMSO, not in water:100.0(Max Conc. mg/mL);250.38(Max Conc. mM)
form :A solid
pka :4.32±0.40(Predicted)
color :White to light yellow
InChIKey :JGPXDNKSIXAZEQ-SBBZOCNPSA-N
SMILES :C12CCC(CC1)[C@H](NC1C(F)=CN=C(C3C4=CC(F)=CN=C4NC=3)N=1)[C@H]2C(O)=O
Safety Information
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Description
Pimodivir is an inhibitor of influenza virus polymerase basic protein 2 (PB2; KD = <0.003 μM). It also binds to glycogen synthase kinase 3β (GSK3β; Ki = ~1.6 μM) and inhibits the activity of Axl and calcium/calmodulin-dependent protein kinase IIβ (CaMKIIβ) by greater than 50% in a panel of 65 human and rat kinases. Pimodivir decreases the replication of seven adamantine- and neuraminidase inhibitor-resistant strains of influenza virus A (EC50s = <0.15-2.8 nM in a cell-based assay). It increases the antiviral activity of oseltamivir , zanamivir , and favipiravir (T-705; ) with 50% combination index (CI50) values of 0.58, 0.64, and 0.89, respectively, in a cell-based assay. Pimodivir increases survival in a mouse model of intranasal influenza A infection when administered at doses of 1, 3, and 10 mg/kg twice per day.Related product price
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