QS11
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- $32 - $2200
- Product name: QS11
- CAS: 944328-88-5
- MF: C36H33N5O2
- MW: 567.69
- EINECS:
- MDL Number:MFCD12912439
- Synonyms:QS11;(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol;(betaS)-beta-[[9-([1,1'-Biphenyl]-4-ylmethyl)-2-[(2,3-dihydro-1H-inden-5-yl)oxy]-9H-purin-6-yl]amino]benzenepropanol;QS11 hydrate;Wnt Synergist, QS11;(S)-2-((9-([1,1'-Biphenyl]-4-ylmethyl)-2-((2,3-dihydro-1H-inden-5-yl)oxy)-9H-purin-6-yl)amino);QS 11 (betaS)-beta-[[9-([1,1'-Biphenyl]-4-ylmethyl)-2-[(2,3-dihydro-1H-inden-5-yl)oxy]-9H-purin-6-yl]amino]benzenepropanol;(2S)-2-[2-(Indan-5-yloxy)-9-(1,1′-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol hydrate
20 prices
Selected condition：
Brand
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 50
- 100mg
- 1g
- ManufacturerAmbeed
- Product numberA820510
- Product descriptionQS11free 98%
- Packaging5mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008280
- Product descriptionQS-11 HYDRATE 95.00%
- Packaging5MG
- Price$272.8
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBRS0000861
- Product descriptionQS-11 95.00%
- Packaging5MG
- Price$283.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS11
- Packaging5mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS11
- Packaging10mg
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS11
- Packaging25mg
- Price$623
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS11
- Packaging50mg
- Price$1118
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS11
- Packaging100mg
- Price$1890
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21247
- Product descriptionQS11 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21247
- Product descriptionQS11 ≥98%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21247
- Product descriptionQS11 ≥98%
- Packaging10mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21247
- Product descriptionQS11 ≥98%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC5139
- Product descriptionQS11(QS11,BML-WN117) >98%
- Packaging100mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC5139
- Product descriptionQS11(QS11,BML-WN117) >98%
- Packaging1g
- Price$2200
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number681668
- Product descriptionWnt Synergist, QS11 A cell-permeable purine compound that binds ARFGAPs (
- Packaging5mg
- Price$591
- Updated2025-07-31
- Buy
- ManufacturerTocris
- Product number3324
- Product descriptionQS11 ≥98%(HPLC)
- Packaging10
- Price$210
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A820510 | QS11free 98% | 5mg | $134 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008280 | QS-11 HYDRATE 95.00% | 5MG | $272.8 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000861 | QS-11 95.00% | 5MG | $283.8 | 2021-12-16 | Buy |
| ApexBio Technology | B7364 | QS11 | 5mg | $156 | 2021-12-16 | Buy |
| ApexBio Technology | B7364 | QS11 | 10mg | $276 | 2021-12-16 | Buy |
| ApexBio Technology | B7364 | QS11 | 25mg | $623 | 2021-12-16 | Buy |
| ApexBio Technology | B7364 | QS11 | 50mg | $1118 | 2021-12-16 | Buy |
| ApexBio Technology | B7364 | QS11 | 100mg | $1890 | 2021-12-16 | Buy |
| Cayman Chemical | 21247 | QS11 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21247 | QS11 ≥98% | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 21247 | QS11 ≥98% | 10mg | $230 | 2024-03-01 | Buy |
| Cayman Chemical | 21247 | QS11 ≥98% | 25mg | $533 | 2024-03-01 | Buy |
| DC Chemicals | DC5139 | QS11(QS11,BML-WN117) >98% | 100mg | $550 | 2021-12-16 | Buy |
| DC Chemicals | DC5139 | QS11(QS11,BML-WN117) >98% | 1g | $2200 | 2021-12-16 | Buy |
| Sigma-Aldrich | 681668 | Wnt Synergist, QS11 A cell-permeable purine compound that binds ARFGAPs ( | 5mg | $591 | 2025-07-31 | Buy |
| Tocris | 3324 | QS11 ≥98%(HPLC) | 10 | $210 | 2021-12-16 | Buy |
Properties
Boiling point :852.2±75.0 °C(Predicted)
Density :1.27
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble in DMSO
form :Pale amber solid
pka :14.46±0.10(Predicted)
color :White to off-white
InChIKey :DOKZLKDGUQWMSX-HKBQPEDESA-N
SMILES :[n]3(c4nc(nc(c4nc3)N[C@H](CO)Cc7ccccc7)Oc5cc6c(cc5)CCC6)Cc1ccc(cc1)c2ccccc2
Density :1.27
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble in DMSO
form :Pale amber solid
pka :14.46±0.10(Predicted)
color :White to off-white
InChIKey :DOKZLKDGUQWMSX-HKBQPEDESA-N
SMILES :[n]3(c4nc(nc(c4nc3)N[C@H](CO)Cc7ccccc7)Oc5cc6c(cc5)CCC6)Cc1ccc(cc1)c2ccccc2
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Wnt Synergist, QS11 is a cell-permeable purine compound that binds GTPase activating proteins of ADP-ribosylation factor (ARFGAPs), including AMAP1 (Kd = 364 nM) and ARFGAP1 (Kd = 620 nM) and acts as a broad specificity ARFGAP1 inhibitor. Wnt Synergist, QS11 has also been reported to block the migration of AMAP1-overexpressing MDA-MB-231 cells (86% inhibition at 2.5 μM).Additionally, Wnt Synergist, QS11 has been shown to work synergistically with Wnt-3a to specifically activate the Wnt/β-catenin signaling pathway in vitro. A Super(8X)TOPFlash reporter assay using HEK293 cells revealed increases in basal transcription activity by application of QS11 (2-fold), Wnt-3a (40-fold), and QS11/Wnt-3a (200-fold).
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