QS11
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- $32 - $2200
- Product name: QS11
- CAS: 944328-88-5
- MF: C36H33N5O2
- MW: 567.69
- EINECS:
- MDL Number:MFCD12912439
- Synonyms:QS11;(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol;(betaS)-beta-[[9-([1,1'-Biphenyl]-4-ylmethyl)-2-[(2,3-dihydro-1H-inden-5-yl)oxy]-9H-purin-6-yl]amino]benzenepropanol;QS11 hydrate;Wnt Synergist, QS11;(S)-2-((9-([1,1'-Biphenyl]-4-ylmethyl)-2-((2,3-dihydro-1H-inden-5-yl)oxy)-9H-purin-6-yl)amino);QS 11 (betaS)-beta-[[9-([1,1'-Biphenyl]-4-ylmethyl)-2-[(2,3-dihydro-1H-inden-5-yl)oxy]-9H-purin-6-yl]amino]benzenepropanol;(2S)-2-[2-(Indan-5-yloxy)-9-(1,1′-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol hydrate
58 prices
Selected condition：
Brand
- aablocks
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 2mg
- 50
- 5mg
- 10mg
- 25mg
- 50mg
- 1mlx10mM(inDMSO)
- 100mg
- 200mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA01DNN4
- Product descriptionQS11 free ≥98%
- Packaging1mg
- Price$36
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNN4
- Product descriptionQS11 free
- Packaging2mg
- Price$44
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNN4
- Product descriptionQS11 free
- Packaging5mg
- Price$59
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNN4
- Product descriptionQS11 free
- Packaging10mg
- Price$82
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNN4
- Product descriptionQS11 free
- Packaging25mg
- Price$147
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNN4
- Product descriptionQS11 free
- Packaging50mg
- Price$211
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNN4
- Product descriptionQS11 free
- Packaging100mg
- Price$307
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DNN4
- Product descriptionQS11 free
- Packaging200mg
- Price$412
- Updated2026-05-29
- Buy
- ManufacturerAmbeed
- Product numberA820510
- Product descriptionQS11free 98%
- Packaging5mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008280
- Product descriptionQS-11 HYDRATE 95.00%
- Packaging5MG
- Price$272.8
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBRS0000861
- Product descriptionQS-11 95.00%
- Packaging5MG
- Price$283.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS11
- Packaging10mg
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS 11
- Packaging10mg
- Price$228
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS11
- Packaging5mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS 11
- Packaging5mg
- Price$167
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7364
- Product descriptionQS 11
- Packaging25mg
- Price$561
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01DNN4 | QS11 free ≥98% | 1mg | $36 | 2026-05-29 | Buy |
| aablocks | AA01DNN4 | QS11 free | 2mg | $44 | 2026-05-29 | Buy |
| aablocks | AA01DNN4 | QS11 free | 5mg | $59 | 2026-05-29 | Buy |
| aablocks | AA01DNN4 | QS11 free | 10mg | $82 | 2026-05-29 | Buy |
| aablocks | AA01DNN4 | QS11 free | 25mg | $147 | 2026-05-29 | Buy |
| aablocks | AA01DNN4 | QS11 free | 50mg | $211 | 2026-05-29 | Buy |
| aablocks | AA01DNN4 | QS11 free | 100mg | $307 | 2026-05-29 | Buy |
| aablocks | AA01DNN4 | QS11 free | 200mg | $412 | 2026-05-29 | Buy |
| Ambeed | A820510 | QS11free 98% | 5mg | $134 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008280 | QS-11 HYDRATE 95.00% | 5MG | $272.8 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000861 | QS-11 95.00% | 5MG | $283.8 | 2021-12-16 | Buy |
| ApexBio Technology | B7364 | QS11 | 10mg | $276 | 2021-12-16 | Buy |
| ApexBio Technology | B7364 | QS 11 | 10mg | $228 | 2026-05-06 | Buy |
| ApexBio Technology | B7364 | QS11 | 5mg | $156 | 2021-12-16 | Buy |
| ApexBio Technology | B7364 | QS 11 | 5mg | $167 | 2026-05-06 | Buy |
| ApexBio Technology | B7364 | QS 11 | 25mg | $561 | 2026-05-06 | Buy |
Properties
Boiling point :852.2±75.0 °C(Predicted)
Density :1.27
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble in DMSO
form :Pale amber solid
pka :14.46±0.10(Predicted)
color :White to off-white
InChIKey :DOKZLKDGUQWMSX-HKBQPEDESA-N
SMILES :[n]3(c4nc(nc(c4nc3)N[C@H](CO)Cc7ccccc7)Oc5cc6c(cc5)CCC6)Cc1ccc(cc1)c2ccccc2
Density :1.27
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble in DMSO
form :Pale amber solid
pka :14.46±0.10(Predicted)
color :White to off-white
InChIKey :DOKZLKDGUQWMSX-HKBQPEDESA-N
SMILES :[n]3(c4nc(nc(c4nc3)N[C@H](CO)Cc7ccccc7)Oc5cc6c(cc5)CCC6)Cc1ccc(cc1)c2ccccc2
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Wnt Synergist, QS11 is a cell-permeable purine compound that binds GTPase activating proteins of ADP-ribosylation factor (ARFGAPs), including AMAP1 (Kd = 364 nM) and ARFGAP1 (Kd = 620 nM) and acts as a broad specificity ARFGAP1 inhibitor. Wnt Synergist, QS11 has also been reported to block the migration of AMAP1-overexpressing MDA-MB-231 cells (86% inhibition at 2.5 μM).Additionally, Wnt Synergist, QS11 has been shown to work synergistically with Wnt-3a to specifically activate the Wnt/β-catenin signaling pathway in vitro. A Super(8X)TOPFlash reporter assay using HEK293 cells revealed increases in basal transcription activity by application of QS11 (2-fold), Wnt-3a (40-fold), and QS11/Wnt-3a (200-fold).
Suppliers and manufacturers
Career Henan Chemica Co
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TargetMol Chemicals Inc.
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Aladdin Scientific
Soochow Chirally Material Science and Technology Co.,Ltd
3B Pharmachem (Wuhan) International Co.,Ltd.
