RADICICOL
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- $32 - $1071
- Product name: RADICICOL
- CAS: 12772-57-5
- MF: C18H17ClO6
- MW: 364.78
- EINECS:
- MDL Number:MFCD06795865
- Synonyms:(1AR,2Z,4E,14R,15AR)-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E][2]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE;[1AS-(1AR*,2Z,4E,14*,15AR*)]-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E][2]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE;5-CHLORO-6-(7,8-EPOXY-10-HYDROXY-2-OXO-3,5-UNDECADIENYL)-BETA-RESORCYLIC ACID MU-LACTONE;FO-4910;KF58332;KF9-A;MONORODENE;RADISICOL
35 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1
- 500μg
- 1mg
- 5mg
- 10mg
- Manufactureraablocks
- Product numberAA000X9R
- Product description(1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione ≥98%
- Packaging1mg
- Price$64
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000X9R
- Product description(1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione ≥98%
- Packaging5mg
- Price$244
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD261946
- Product descriptionRadicicol 97%
- Packaging5MG
- Price$480
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD261946
- Product descriptionRadicicol 97%
- Packaging1MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0021-M005
- Product descriptionRadicicol ≥99%(HPLC)
- Packaging5mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0021-M005
- Product descriptionRadicicol ≥99%(HPLC)
- Packaging5mg
- Price$180
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0021-M001
- Product descriptionRadicicol ≥99%(HPLC)
- Packaging1mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0021-M001
- Product descriptionRadicicol ≥99%(HPLC)
- Packaging1mg
- Price$45
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product number2024AH
- Product descriptionRadicicol
- Packaging5mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4067
- Product descriptionRadicicol
- Packaging5mg
- Price$359
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4067
- Product descriptionRadicicol
- Packaging1mg
- Price$74
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4067
- Product descriptionRadicicol
- Packaging1mg
- Price$98
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-N6769
- Product descriptionRadicicol 99.47%
- Packaging1mg
- Price$273
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6769
- Product descriptionRadicicol 99.47%
- Packaging5mg
- Price$671
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6769
- Product descriptionRadicicol 99.47%
- Packaging10mg
- Price$1071
- Updated2026-05-26
- Buy
- ManufacturerAvaChem
- Product number6723
- Product descriptionRadicicol 98%
- Packaging1mg
- Price$50
- Updated2026-05-22
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000X9R | (1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione ≥98% | 1mg | $64 | 2026-05-25 | Buy |
| aablocks | AA000X9R | (1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione ≥98% | 5mg | $244 | 2026-05-25 | Buy |
| ACHEMBLOCK | AD261946 | Radicicol 97% | 5MG | $480 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD261946 | Radicicol 97% | 1MG | $145 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CN2-0021-M005 | Radicicol ≥99%(HPLC) | 5mg | $160 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0021-M005 | Radicicol ≥99%(HPLC) | 5mg | $180 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0021-M001 | Radicicol ≥99%(HPLC) | 1mg | $40 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0021-M001 | Radicicol ≥99%(HPLC) | 1mg | $45 | 2026-05-06 | Buy |
| AK Scientific | 2024AH | Radicicol | 5mg | $302 | 2021-12-16 | Buy |
| ApexBio Technology | A4067 | Radicicol | 5mg | $359 | 2026-05-06 | Buy |
| ApexBio Technology | A4067 | Radicicol | 1mg | $74 | 2021-12-16 | Buy |
| ApexBio Technology | A4067 | Radicicol | 1mg | $98 | 2026-05-06 | Buy |
| Arctom | HY-N6769 | Radicicol 99.47% | 1mg | $273 | 2026-05-26 | Buy |
| Arctom | HY-N6769 | Radicicol 99.47% | 5mg | $671 | 2026-05-26 | Buy |
| Arctom | HY-N6769 | Radicicol 99.47% | 10mg | $1071 | 2026-05-26 | Buy |
| AvaChem | 6723 | Radicicol 98% | 1mg | $50 | 2026-05-22 | Buy |
Properties
Melting point :193.5°
alpha :D20 +203° (chloroform)
Boiling point :656.2±55.0 °C(Predicted)
Density :1.364±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :ethanol: 10 mg/mL
form :solid
pka :6.29±0.40(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2+,5-3+
InChIKey :WYZWZEOGROVVHK-ZUVMSYQZSA-N
SMILES :Clc1c2c(c(cc1O)O)C(=O)OC(CC3OC3\C=C\C=C\C(=O)C2)C
alpha :D20 +203° (chloroform)
Boiling point :656.2±55.0 °C(Predicted)
Density :1.364±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :ethanol: 10 mg/mL
form :solid
pka :6.29±0.40(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2+,5-3+
InChIKey :WYZWZEOGROVVHK-ZUVMSYQZSA-N
SMILES :Clc1c2c(c(cc1O)O)C(=O)OC(CC3OC3\C=C\C=C\C(=O)C2)C
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
Radicicol is a natural product derived from D. chlamydosporia with antibiotic, antifungal, and antimalarial properties. It binds and inhibits heat shock protein 90 (Hsp90) with nanomolar affinity. This interaction inhibits p23 from associating with Hsp90, suppresses signaling through HIF-1α, and produces decreased levels of progesterone receptor, Raf-1, p185erb82, and mutant p53. Radicicol also binds to and inhibits DNA topoisomerase type II proteins and GRP94 through an ATPase domain common to Hsp90.Related product price
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