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ChemicalBook >> CAS DataBase List >> ROCAGLAMIDE

ROCAGLAMIDE

ROCAGLAMIDE price.
  • $101 - $4970
  • Product name: ROCAGLAMIDE
  • CAS: 84573-16-0
  • MF: C29H31NO7
  • MW: 505.56
  • EINECS:
  • MDL Number:MFCD08702699
  • Synonyms:ROCAGLAMIDE;(1R)-2,3,3a,8b-Tetrahydro-1α,8bβ-dihydroxy-6,8-dimethoxy-3aβ-(4-methoxyphenyl)-N,N-dimethyl-3β-phenyl-1H-cyclopenta[b]benzofuran-2α-carboxamide;(1R)-N,N-Dimethyl-1α,8bβ-dihydroxy-3β-phenyl-3aβ-(4-methoxyphenyl)-6,8-dimethoxy-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2α-carboxamide;2,3,3a,8b-Tetrahydro-1α,8bβ-dihydroxy-6,8-dimethoxy-3aβ-(4-methoxyphenyl)-N,N-dimethyl-3β-phenyl-1H-cyclopenta[b]benzofuran-2α-carboxamide;2,3,3a,8b-Tetrahydro-N,N-dimethyl-1α,8bβ-dihydroxy-6,8-dimethoxy-3β-phenyl-3aβ-(4-methoxyphenyl)-1H-cyclopenta[b]benzofuran-2α-carboxamide;N,N-Dimethyl-1α,8bβ-dihydroxy-6,8-dimethoxy-3β-phenyl-3aβ-(4-methoxyphenyl)-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2α-carboxamide;(1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide;NSC 326408
27 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 001
  • 100μg
  • 100ug
  • 500ug
  • 003
  • 500μg
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010351
  • Product descriptionROCAGLAMIDE 95.00%
  • Packaging5MG
  • Price$499.38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010351
  • Product descriptionROCAGLAMIDE 95.00%
  • Packaging1G
  • Price$1428
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019967
  • Product descriptionRocaglamide ≥98%
  • Packaging5mg
  • Price$535
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN97339
  • Product descriptionRocaglamide ≥98%
  • Packaging5mg
  • Price$593
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019967
  • Product descriptionRocaglamide ≥98%
  • Packaging10mg
  • Price$940
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14841
  • Product descriptionRocaglamide ≥95%
  • Packaging500μg
  • Price$101
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14841
  • Product descriptionRocaglamide ≥95%
  • Packaging1mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5246
  • Product descriptionRocaglamide 99.34%
  • Packaging500ug
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5246
  • Product descriptionRocaglamide 99.34%
  • Packaging1mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5246
  • Product descriptionRocaglamide 99.34%
  • Packaging5mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5246
  • Product descriptionRocaglamide 99.34%
  • Packaging10mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5246
  • Product descriptionRocaglamide 99.34%
  • Packaging25mg
  • Price$1850
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5246
  • Product descriptionRocaglamide 99.34%
  • Packaging50mg
  • Price$3150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5246
  • Product descriptionRocaglamide 99.34%
  • Packaging100mg
  • Price$4950
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000646
  • Product descriptionRocaglamide 98+%
  • Packaging5mg
  • Price$546
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000646
  • Product descriptionRocaglamide 98+%
  • Packaging10mg
  • Price$840
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0010351 ROCAGLAMIDE 95.00% 5MG $499.38 2021-12-16 Buy
American Custom Chemicals Corporation API0010351 ROCAGLAMIDE 95.00% 1G $1428 2021-12-16 Buy
Arctom AS019967 Rocaglamide ≥98% 5mg $535 2021-12-16 Buy
Arctom CFN97339 Rocaglamide ≥98% 5mg $593 2021-12-16 Buy
Arctom AS019967 Rocaglamide ≥98% 10mg $940 2021-12-16 Buy
Cayman Chemical 14841 Rocaglamide ≥95% 500μg $101 2024-03-01 Buy
Cayman Chemical 14841 Rocaglamide ≥95% 1mg $152 2024-03-01 Buy
ChemScene CS-5246 Rocaglamide 99.34% 500ug $200 2021-12-16 Buy
ChemScene CS-5246 Rocaglamide 99.34% 1mg $250 2021-12-16 Buy
ChemScene CS-5246 Rocaglamide 99.34% 5mg $550 2021-12-16 Buy
ChemScene CS-5246 Rocaglamide 99.34% 10mg $950 2021-12-16 Buy
ChemScene CS-5246 Rocaglamide 99.34% 25mg $1850 2021-12-16 Buy
ChemScene CS-5246 Rocaglamide 99.34% 50mg $3150 2021-12-16 Buy
ChemScene CS-5246 Rocaglamide 99.34% 100mg $4950 2021-12-16 Buy
Crysdot CD31000646 Rocaglamide 98+% 5mg $546 2021-12-16 Buy
Crysdot CD31000646 Rocaglamide 98+% 10mg $840 2021-12-16 Buy

Properties

Melting point :117-118 °C
Boiling point :667.3±55.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO or Ethanol
form :film
pka :11.70±0.70(Predicted)
color :colorless
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. Protect from exposure to light and moisture.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Rocaglamide is an anti-inflammatory, insecticidal, and anticancer tetrahydrobenzofuran isolated from Aglaia species. It has been shown to inhibit both TNF-α and the activation of NF-κB in Jurkat T cells with IC50 values in the nanomolar range. At 25 nM, rocaglamide induces apoptosis in various human leukemia cell lines, activating p38 MAPK/JNK and suppressing ERK. Rocaglamide also reduces IFN-γ, TNF-α, IL-2, and IL-4 production in peripheral blood T cells at a concentration of 50 nM. Furthermore, rocaglamide can inhibit the T cell expression of the immune response transcription factor, nuclear factor of activated T cells.

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