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ChemicalBook >> CAS DataBase List >> Radotinib

Radotinib

$32 - $1600
Product name: Radotinib
CAS: 926037-48-1
MF: C27H21F3N8O
MW: 530.5
EINECS:
MDL Number:MFCD27956910
Synonyms:IY5511;Radotinib;Radotinib(IY-5511);4-Methyl-N-[3-(4-methylimidazol-1-yl)-5-trifluoromethylphenyl]-3-(4-(pyrazin-2-yl)pyrimidin-2-ylamino)benzamide;4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phe...;Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(2-pyrazinyl)-2-pyrimidinyl]amino]-;RADOTINIB; IY5511 HCL.;IY5511 HCl.

Price35 Properties Safety Information Description

35 prices

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Brand

AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Biorbyt Ltd
Biosynth Carbosynth
Cayman Chemical
Chemenu
Crysdot
DC Chemicals
TRC

Package

1mg
5MG
10mg
25mg
50mg
100mg
10mM(in1mLDMSO)
10mM(in 1mL DMSO)
250mg
500mg
1g

ManufacturerAK Scientific
Product number2192CW
Product descriptionRadotinib
Packaging50mg
Price$387
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0026218
Product descriptionRADOTINIB 95.00%
Packaging5MG
Price$497.4
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB5846
Product descriptionRadotinib(IY-5511)
Packaging5mg
Price$55
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB5846
Product descriptionRadotinib(IY-5511)
Packaging10mM(in1mLDMSO)
Price$66
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB5846
Product descriptionRadotinib(IY-5511)
Packaging10mg
Price$83
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB5846
Product descriptionRadotinib(IY-5511)
Packaging10mM(in 1mL DMSO)
Price$120
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB5846
Product descriptionRadotinib(IY-5511)
Packaging25mg
Price$165
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB5846
Product descriptionRadotinib(IY-5511)
Packaging50mg
Price$275
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB5846
Product descriptionRadotinib(IY-5511)
Packaging50mg
Price$320
Updated2021-12-16
Buy

ManufacturerBiorbyt Ltd
Product numberorb1223632
Product descriptionRadotinib >98%(HPLC)
Packaging500mg
Price$1140
Updated2026-05-06
Buy

ManufacturerBiorbyt Ltd
Product numberorb1223632
Product descriptionRadotinib >98%(HPLC)
Packaging100mg
Price$510
Updated2026-05-06
Buy

ManufacturerBiorbyt Ltd
Product numberorb1223632
Product descriptionRadotinib >98%(HPLC)
Packaging50mg
Price$290
Updated2026-05-06
Buy

ManufacturerBiorbyt Ltd
Product numberorb1223632
Product descriptionRadotinib >98%(HPLC)
Packaging25mg
Price$190
Updated2026-05-06
Buy

ManufacturerBiorbyt Ltd
Product numberorb1223632
Product descriptionRadotinib >98%(HPLC)
Packaging10mg
Price$110
Updated2026-05-06
Buy

ManufacturerBiorbyt Ltd
Product numberorb1223632
Product descriptionRadotinib >98%(HPLC)
Packaging5mg
Price$80
Updated2026-05-06
Buy

ManufacturerBiosynth Carbosynth
Product numberFR103403
Product descriptionRadotinib
Packaging250mg
Price$500
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	2192CW	Radotinib	50mg	$387	2021-12-16	Buy
American Custom Chemicals Corporation	API0026218	RADOTINIB 95.00%	5MG	$497.4	2021-12-16	Buy
ApexBio Technology	B5846	Radotinib(IY-5511)	5mg	$55	2026-05-06	Buy
ApexBio Technology	B5846	Radotinib(IY-5511)	10mM(in1mLDMSO)	$66	2026-05-06	Buy
ApexBio Technology	B5846	Radotinib(IY-5511)	10mg	$83	2026-05-06	Buy
ApexBio Technology	B5846	Radotinib(IY-5511)	10mM(in 1mL DMSO)	$120	2021-12-16	Buy
ApexBio Technology	B5846	Radotinib(IY-5511)	25mg	$165	2026-05-06	Buy
ApexBio Technology	B5846	Radotinib(IY-5511)	50mg	$275	2026-05-06	Buy
ApexBio Technology	B5846	Radotinib(IY-5511)	50mg	$320	2021-12-16	Buy
Biorbyt Ltd	orb1223632	Radotinib >98%(HPLC)	500mg	$1140	2026-05-06	Buy
Biorbyt Ltd	orb1223632	Radotinib >98%(HPLC)	100mg	$510	2026-05-06	Buy
Biorbyt Ltd	orb1223632	Radotinib >98%(HPLC)	50mg	$290	2026-05-06	Buy
Biorbyt Ltd	orb1223632	Radotinib >98%(HPLC)	25mg	$190	2026-05-06	Buy
Biorbyt Ltd	orb1223632	Radotinib >98%(HPLC)	10mg	$110	2026-05-06	Buy
Biorbyt Ltd	orb1223632	Radotinib >98%(HPLC)	5mg	$80	2026-05-06	Buy
Biosynth Carbosynth	FR103403	Radotinib	250mg	$500	2021-12-16	Buy

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Properties

Density :1.40±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥26.55 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :12.94±0.70(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H317	May cause an allergic skin reaction	Sensitisation, Skin	Category 1	Warning	P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318	Causes serious eye damage	Serious eye damage/eye irritation	Category 1	Danger	P280, P305+P351+P338, P310
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled	Sensitisation, respiratory	Category 1	Danger	P261, P285, P304+P341, P342+P311,P501
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning
H341	Suspected of causing genetic defects	Germ cell mutagenicity	Category 2	Warning	P201,P202, P281, P308+P313, P405,P501
H361	Suspected of damaging fertility or the unborn child	Reproductive toxicity	Category 2	Warning	P201, P202, P281, P308+P313, P405,P501
H370	Causes damage to organs	Specific target organ toxicity, single exposure	Category 1	Danger	P260, P264, P270, P307+P311, P321,P405, P501
H413	May cause long lasting harmful effects to aquatic life	Hazardous to the aquatic environment, long-term hazard	Category 4

Precautionary statements:

P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P284	Wear respiratory protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313	IF exposed or concerned: Get medical advice/attention.
P310	Immediately call a POISON CENTER or doctor/physician.
P321	Specific treatment (see … on this label).
P330	Rinse mouth.
P333+P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363	Wash contaminated clothing before reuse.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

Radotinib, an inhibitor of Bcr–Abl tyrosine kinase,was approved in January 2012 in Korea as a second-line treatment for chronic myeloid leukemia (CML). Radotinib is a TKI with a similar structure to the second-generation TKI, nilotinib, in which a pyridyl group has been replaced with a pyrazinemoiety. The in vitro activity of radotinib against a variety of tumor cell lines is disclosed in an issued patent. Radotinib was significantly more potent than imatinib in all of the cell lines tested. The synthesis of radotinib via amide coupling is described in the patent literature.

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Suppliers and manufacturers

career henan chemical co

$1.00 /1KG
Radotinib CAS:926037-48-1

TargetMol Chemicals Inc.

$39.00 /5mg
Radotinib CAS:926037-48-1

ATK CHEMICAL COMPANY LIMITED

BOC Sciences

Hubei Ipure Biology Co., Ltd

HONG KONG IPURE BIOLOGY CO.,LIMITED

Shenzhen Shengda Pharma Limited

Zhejiang J&C Biological Technology Co.,Limited

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Hefei TNJ Chemical Industry Co.,Ltd.

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Radotinib

Properties

Safety Information

Description

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