Rolapitant
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- $32 - $1420
- Product name: Rolapitant
- CAS: 552292-08-7
- MF: C25H26F6N2O2
- MW: 500.48
- EINECS:812-147-5
- MDL Number:MFCD23105917
- Synonyms:Rolapitant;(5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one hydrochloride.;Rolapitant HCl;Rolapitant(sch619734);(5S,8S)-8-[[[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl]oxy]methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one;(5S,8S)-8-({(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one;1,7-Diazaspiro[4.5]decan-2-one,8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-,(5S,8S)-;(5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one
36 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- ManufacturerAK Scientific
- Product number3912BB
- Product descriptionRolapitant
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3912BB
- Product descriptionRolapitant
- Packaging10mg
- Price$336
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3912BB
- Product descriptionRolapitant
- Packaging5mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitant HCl
- Packaging25mg
- Price$348
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitantHCl
- Packaging25mg
- Price$378
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitant HCl
- Packaging50mg
- Price$580
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitantHCl
- Packaging50mg
- Price$630
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitant HCl
- Packaging100mg
- Price$869
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitantHCl
- Packaging100mg
- Price$945
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitant HCl
- Packaging5mg
- Price$145
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitant HCl
- Packaging10mg
- Price$217
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitant HCl
- Packaging1mg
- Price$73
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5910
- Product descriptionRolapitantHCl
- Packaging1mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1223100
- Product descriptionRolapitant >98%(HPLC)
- Packaging2mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1223100
- Product descriptionRolapitant >98%(HPLC)
- Packaging10mg
- Price$190
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1223100
- Product descriptionRolapitant >98%(HPLC)
- Packaging5mg
- Price$140
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3912BB | Rolapitant | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 3912BB | Rolapitant | 10mg | $336 | 2021-12-16 | Buy |
| AK Scientific | 3912BB | Rolapitant | 5mg | $226 | 2021-12-16 | Buy |
| ApexBio Technology | B5910 | Rolapitant HCl | 25mg | $348 | 2026-05-06 | Buy |
| ApexBio Technology | B5910 | RolapitantHCl | 25mg | $378 | 2021-12-16 | Buy |
| ApexBio Technology | B5910 | Rolapitant HCl | 50mg | $580 | 2026-05-06 | Buy |
| ApexBio Technology | B5910 | RolapitantHCl | 50mg | $630 | 2021-12-16 | Buy |
| ApexBio Technology | B5910 | Rolapitant HCl | 100mg | $869 | 2026-05-06 | Buy |
| ApexBio Technology | B5910 | RolapitantHCl | 100mg | $945 | 2021-12-16 | Buy |
| ApexBio Technology | B5910 | Rolapitant HCl | 5mg | $145 | 2026-05-06 | Buy |
| ApexBio Technology | B5910 | Rolapitant HCl | 10mg | $217 | 2026-05-06 | Buy |
| ApexBio Technology | B5910 | Rolapitant HCl | 1mg | $73 | 2026-05-06 | Buy |
| ApexBio Technology | B5910 | RolapitantHCl | 1mg | $79 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb1223100 | Rolapitant >98%(HPLC) | 2mg | $110 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1223100 | Rolapitant >98%(HPLC) | 10mg | $190 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1223100 | Rolapitant >98%(HPLC) | 5mg | $140 | 2026-05-06 | Buy |
Properties
Boiling point :523.5±50.0 °C(Predicted)
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 16 mg/ml; Ethanol: 3 mg/ml
pka :15.88±0.40(Predicted)
form :Powder
color :White to off-white
InChIKey :FIVSJYGQAIEMOC-ZGNKEGEESA-N
SMILES :N1[C@@]2(CC[C@@](CO[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)(C3=CC=CC=C3)NC2)CCC1=O
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 16 mg/ml; Ethanol: 3 mg/ml
pka :15.88±0.40(Predicted)
form :Powder
color :White to off-white
InChIKey :FIVSJYGQAIEMOC-ZGNKEGEESA-N
SMILES :N1[C@@]2(CC[C@@](CO[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)(C3=CC=CC=C3)NC2)CCC1=O
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
ChEBI: An azaspiro compound that is 1,7-diazaspiro[4.5]decan-2-one carrying additional phenyl and 1-{[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl substituents at position 8. Used (in the form of the hydrochloride hydrate) for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.More related product prices
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