SHA 68
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- $32 - $1305
- Product name: SHA 68
- CAS: 847553-89-3
- MF: C26H24FN3O3
- MW: 445.49
- EINECS:
- MDL Number:MFCD22683843
- Synonyms:SHA 68;N-(4-fluorobenzyl)-3-oxo-1,1-diphenyltetrahydro-1H-oxazolo[3,4-a]pyrazine-7(3H)-carboxamide;N-[(4-Fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide;3H-Oxazolo[3,4-a]pyrazine-7(1H)-carboxamide, N-[(4-fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-;N-(4-Fluorobenzyl)-3-oxo-1,1-diphenyltetrahydro-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide;N-[(4-fluorophenyl)methyl]-3-oxo-1,1-diphenyl-hexahydro-1H-[1,3]oxazolo[3,4-a]pyrazine-7-carboxamide
28 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 2mg
- 1mg
- 50
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product numberV4440
- Product descriptionSHA68
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV4440
- Product descriptionSHA68
- Packaging25mg
- Price$546
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5625
- Product descriptionSHA 68
- Packaging50mg
- Price$732
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5625
- Product descriptionSHA68
- Packaging50mg
- Price$1305
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5625
- Product descriptionSHA 68
- Packaging10mg
- Price$203
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5625
- Product descriptionSHA68
- Packaging10mg
- Price$322
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1089895
- Product descriptionSHA 68
- Packaging10mg
- Price$220
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1089895
- Product descriptionSHA 68
- Packaging5mg
- Price$160
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1089895
- Product descriptionSHA 68
- Packaging2mg
- Price$130
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1089895
- Product descriptionSHA 68
- Packaging50mg
- Price$750
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1089895
- Product descriptionSHA 68
- Packaging25mg
- Price$460
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number21512
- Product descriptionSHA-68 ≥95%
- Packaging10mg
- Price$160
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21512
- Product descriptionSHA-68 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21512
- Product descriptionSHA-68 ≥95%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21512
- Product descriptionSHA-68 ≥95%
- Packaging5mg
- Price$88
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21512
- Product descriptionSHA-68 ≥95%
- Packaging5mg
- Price$97
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | V4440 | SHA68 | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | V4440 | SHA68 | 25mg | $546 | 2021-12-16 | Buy |
| ApexBio Technology | B5625 | SHA 68 | 50mg | $732 | 2026-05-06 | Buy |
| ApexBio Technology | B5625 | SHA68 | 50mg | $1305 | 2021-12-16 | Buy |
| ApexBio Technology | B5625 | SHA 68 | 10mg | $203 | 2026-05-06 | Buy |
| ApexBio Technology | B5625 | SHA68 | 10mg | $322 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb1089895 | SHA 68 | 10mg | $220 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1089895 | SHA 68 | 5mg | $160 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1089895 | SHA 68 | 2mg | $130 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1089895 | SHA 68 | 50mg | $750 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1089895 | SHA 68 | 25mg | $460 | 2026-05-06 | Buy |
| Cayman Chemical | 21512 | SHA-68 ≥95% | 10mg | $160 | 2024-03-01 | Buy |
| Cayman Chemical | 21512 | SHA-68 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21512 | SHA-68 ≥95% | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 21512 | SHA-68 ≥95% | 5mg | $88 | 2024-03-01 | Buy |
| Cayman Chemical | 21512 | SHA-68 ≥95% | 5mg | $97 | 2026-04-30 | Buy |
Properties
Boiling point :727.8±60.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 16 mg/ml; DMSO: 14 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
form :A crystalline solid
pka :13.32±0.40(Predicted)
color :White to off-white
InChI :InChI=1S/C26H24FN3O3/c27-22-13-11-19(12-14-22)17-28-24(31)29-15-16-30-23(18-29)26(33-25(30)32,20-7-3-1-4-8-20)21-9-5-2-6-10-21/h1-14,23H,15-18H2,(H,28,31)
InChIKey :SFRQIPRTNYHJHP-UHFFFAOYSA-N
SMILES :C12C(C3=CC=CC=C3)(C3=CC=CC=C3)OC(=O)N1CCN(C(NCC1=CC=C(F)C=C1)=O)C2
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 16 mg/ml; DMSO: 14 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
form :A crystalline solid
pka :13.32±0.40(Predicted)
color :White to off-white
InChI :InChI=1S/C26H24FN3O3/c27-22-13-11-19(12-14-22)17-28-24(31)29-15-16-30-23(18-29)26(33-25(30)32,20-7-3-1-4-8-20)21-9-5-2-6-10-21/h1-14,23H,15-18H2,(H,28,31)
InChIKey :SFRQIPRTNYHJHP-UHFFFAOYSA-N
SMILES :C12C(C3=CC=CC=C3)(C3=CC=CC=C3)OC(=O)N1CCN(C(NCC1=CC=C(F)C=C1)=O)C2
Safety Information
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Description
SHA-68 is an antagonist of the neuropeptide S receptor (NPSR; IC50s = 22 and 23.8 nM for the NPSR Asn107 and NPSR Ile107 isoforms, respectively). It is selective for NPSR over a panel of 14 G protein-coupled receptors exhibiting no activity at a concentration of 10 μM. SHA-68 (50 mg/kg) reduces NPS-induced horizontal activity and vertical rearing and climbing in mice. SHA-68 also reduces conditioned reinstatement of cocaine seeking in rats.More related product prices
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