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ChemicalBook >> CAS DataBase List >> STAUROSPORINE

STAUROSPORINE

STAUROSPORINE price.
  • $32 - $3200
  • Product name: STAUROSPORINE
  • CAS: 62996-74-1
  • MF: C28H26N4O3
  • MW: 466.54
  • EINECS:613-127-7
  • MDL Number:MFCD18252446
  • Synonyms:9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, [9S-(9α,10β,11β,13α)]-;InSolution Staurosporine, Streptomyces sp;Staurosporineinsolution;9,13-Epoxy-1H,9H-diindolo1,2,3-gh:3,2,1-lmpyrrolo3,4-j1,7benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)-;Staurosporine, Antibiotic AM-2282;(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one;Antibiotic 230;CGP 39360
53 prices
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Ark Pharm
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 0.1mg
  • 100μg
  • 100ug
  • 200μg
  • 250μg
  • 500μg
  • 0.5mg
  • 1mg
  • 0.001g
  • 2mg
  • 5mg
  • 10mg
  • 50mg
  • 10mM(in 1mL DMSO)
  • 25mg
  • 100U
  • 100mg
  • 250mg
  • 1g
  • 1ml
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0022-C500
  • Product descriptionStaurosporine ≥98%(HPLC)
  • Packaging500μg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0022-M001
  • Product descriptionStaurosporine ≥98%(HPLC)
  • Packaging1mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-58722
  • Product descriptionStaurosporine 98%
  • Packaging0.001g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0336
  • Product descriptionStaurosporine
  • Packaging5mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62837
  • Product descriptionStaurosporine, 99+%
  • Packaging1mg
  • Price$152
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67198
  • Product descriptionStaurosporine, 1 mg/ml in DMSO sterile-filtered
  • Packaging1ml
  • Price$278
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62837
  • Product descriptionStaurosporine, 99+%
  • Packaging5mg
  • Price$393
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62837
  • Product descriptionStaurosporine, 99+%
  • Packaging10mg
  • Price$704
  • Updated2023-06-20
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8192
  • Product descriptionStaurosporine
  • Packaging10mM(in 1mL DMSO)
  • Price$205
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIS0504
  • Product descriptionStaurosporine from Streptomyces sp.
  • Packaging10mg
  • Price$182
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIS0504
  • Product descriptionStaurosporine from Streptomyces sp.
  • Packaging25mg
  • Price$319
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIS0504
  • Product descriptionStaurosporine from Streptomyces sp.
  • Packaging100mg
  • Price$566
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60182
  • Product descriptionStaurosporine ≥98%
  • Packaging10mg
  • Price$358
  • Updated2021-12-16
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  • ManufacturerArk Pharm
  • Product numberP000622009
  • Product descriptionStaurosporine 98+%
  • Packaging2mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000622009
  • Product descriptionStaurosporine 98+%
  • Packaging5mg
  • Price$291
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000622009
  • Product descriptionStaurosporine 98+%
  • Packaging10mg
  • Price$498
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0022-C500 Staurosporine ≥98%(HPLC) 500μg $90 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0022-M001 Staurosporine ≥98%(HPLC) 1mg $120 2021-12-16 Buy
AHH MT-58722 Staurosporine 98% 0.001g $230 2021-12-16 Buy
AK Scientific V0336 Staurosporine 5mg $98 2021-12-16 Buy
Alfa Aesar J62837 Staurosporine, 99+% 1mg $152 2023-06-20 Buy
Alfa Aesar J67198 Staurosporine, 1 mg/ml in DMSO sterile-filtered 1ml $278 2023-06-20 Buy
Alfa Aesar J62837 Staurosporine, 99+% 5mg $393 2023-06-20 Buy
Alfa Aesar J62837 Staurosporine, 99+% 10mg $704 2023-06-20 Buy
ApexBio Technology A8192 Staurosporine 10mM(in 1mL DMSO) $205 2021-12-16 Buy
Apolloscientific BIS0504 Staurosporine from Streptomyces sp. 10mg $182 2021-12-16 Buy
Apolloscientific BIS0504 Staurosporine from Streptomyces sp. 25mg $319 2021-12-16 Buy
Apolloscientific BIS0504 Staurosporine from Streptomyces sp. 100mg $566 2021-12-16 Buy
Arctom CFN60182 Staurosporine ≥98% 10mg $358 2021-12-16 Buy
Ark Pharm P000622009 Staurosporine 98+% 2mg $152 2021-12-16 Buy
Ark Pharm P000622009 Staurosporine 98+% 5mg $291 2021-12-16 Buy
Ark Pharm P000622009 Staurosporine 98+% 10mg $498 2021-12-16 Buy

Properties

Melting point :270°C
alpha :D25 +35.0° (c = 1 in methanol); D22 +56.1° (c = 0.14 in methanol)
Boiling point :677.5±55.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
RTECS :KD5084000
storage temp. :2-8°C
solubility :DMSO: soluble
form :White to pale yellow solid
pka :14.25±0.70(Predicted)
color :Off white to pale yellow
Water Solubility :Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot acetone and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water.
BRN :1060573
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
InChIKey :HKSZLNNOFSGOKW-WIFUGMKFSA-N
CAS DataBase Reference :62996-74-1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.

Description

Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. It inhibits rat recombinant PKC-α approximately 100- and 1,000-fold better than PKC-δ and PKC-ζ, respectively. However, Stsp is non-selective in that it also inhibits the activity of a variety of other protein kinases, not only PKC isoforms. The biological effects of Stsp include cytotoxicity, relaxation of smooth muscle, and regulation of eNOS gene expression.

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