STF-118804
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- $24 - $2245.7
- Product name: STF-118804
- CAS: 894187-61-2
- MF: C25H23N3O4S
- MW: 461.53
- EINECS:-0
- MDL Number:MFCD14918065
- Synonyms:STF-118804;Benzamide, 4-[5-methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)-;4-[5-Methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)benzamide;4-(5-methyl-4-((phenylsulfonyl)methyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide;CS-1510;STF-118804, AGN-PC-0329XY, AKOS001906141, MCULE-5035356713;AGN-PC-0329XY;AGN-PC-0329XY; AKOS001906141; MCULE-5035356713; STF-118804
60 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1.00g
- 1000mg
- 10mM*1mLinDMSO(Solution)
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 5g
- 5
- 5.00g
- 25
- 5 mg
- 1mg
- 5mg
- 10mg
- 50mg
- 10mM(in 1mL DMSO)
- 25mg
- 100mg
- 200mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00GT9G
- Product descriptionSTF-118804 ≥98%(HPLC)
- Packaging5mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT9G
- Product descriptionSTF-118804 99%
- Packaging1mg
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT9G
- Product descriptionSTF-118804 ≥98%(HPLC)
- Packaging10mg
- Price$65
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT9G
- Product descriptionSTF-118804 ≥98%(HPLC)
- Packaging25mg
- Price$142
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT9G
- Product descriptionSTF-118804
- Packaging50mg
- Price$224
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT9G
- Product descriptionSTF-118804 ≥98%(HPLC)
- Packaging200mg
- Price$825
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product numberSYN5148
- Product descriptionSTF-118804
- Packaging100mg
- Price$1185
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA692427
- Product descriptionSTF-118804 98+%
- Packaging1g
- Price$581
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA692427
- Product descriptionSTF-118804 98+%
- Packaging250mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA692427
- Product descriptionSTF-118804 98+%
- Packaging100mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA692427
- Product descriptionSTF-118804 98+%
- Packaging5mg
- Price$41
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA692427
- Product descriptionSTF-118804 98+%
- Packaging10mg
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA692427
- Product descriptionSTF-118804 98+%
- Packaging1mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA692427
- Product descriptionSTF-118804 98+%
- Packaging50mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2033
- Product descriptionSTF-118804
- Packaging10mM(in 1mL DMSO)
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2033
- Product descriptionSTF-118804
- Packaging5mg
- Price$77
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GT9G | STF-118804 ≥98%(HPLC) | 5mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00GT9G | STF-118804 99% | 1mg | $24 | 2026-05-28 | Buy |
| aablocks | AA00GT9G | STF-118804 ≥98%(HPLC) | 10mg | $65 | 2026-05-28 | Buy |
| aablocks | AA00GT9G | STF-118804 ≥98%(HPLC) | 25mg | $142 | 2026-05-28 | Buy |
| aablocks | AA00GT9G | STF-118804 | 50mg | $224 | 2026-05-28 | Buy |
| aablocks | AA00GT9G | STF-118804 ≥98%(HPLC) | 200mg | $825 | 2026-05-28 | Buy |
| AK Scientific | SYN5148 | STF-118804 | 100mg | $1185 | 2021-12-16 | Buy |
| Ambeed | A692427 | STF-118804 98+% | 1g | $581 | 2021-12-16 | Buy |
| Ambeed | A692427 | STF-118804 98+% | 250mg | $232 | 2021-12-16 | Buy |
| Ambeed | A692427 | STF-118804 98+% | 100mg | $116 | 2021-12-16 | Buy |
| Ambeed | A692427 | STF-118804 98+% | 5mg | $41 | 2021-12-16 | Buy |
| Ambeed | A692427 | STF-118804 98+% | 10mg | $53 | 2021-12-16 | Buy |
| Ambeed | A692427 | STF-118804 98+% | 1mg | $24 | 2021-12-16 | Buy |
| Ambeed | A692427 | STF-118804 98+% | 50mg | $89 | 2021-12-16 | Buy |
| ApexBio Technology | B2033 | STF-118804 | 10mM(in 1mL DMSO) | $100 | 2021-12-16 | Buy |
| ApexBio Technology | B2033 | STF-118804 | 5mg | $77 | 2026-05-06 | Buy |
Properties
Melting point :187-190°C
Density :1.281±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.00±0.46(Predicted)
color :White to Off-White
InChI :1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
InChIKey :DLFCEZOMHBPDGI-UHFFFAOYSA-N
SMILES :O=C(C1=CC=C(C2=NC(CS(=O)(C3=CC=C(C)C=C3)=O)=C(C)O2)C=C1)NCC4=CN=CC=C4
Density :1.281±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.00±0.46(Predicted)
color :White to Off-White
InChI :1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
InChIKey :DLFCEZOMHBPDGI-UHFFFAOYSA-N
SMILES :O=C(C1=CC=C(C2=NC(CS(=O)(C3=CC=C(C)C=C3)=O)=C(C)O2)C=C1)NCC4=CN=CC=C4
Safety Information
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Description
Nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide into nicotinamide mononucleotide (NMN), which is subsequently converted to NAD+ by NMN adenyltransferase. Cancer cells commonly have an unusually high rate of NAD+ turnover, suggesting that inhibition of Nampt might selectively target cancer cells. STF-118804 is a small molecule inhibitor of Nampt (IC50s = 3-6 nM) that prevents NAD+ synthesis from nicotinamide. It inhibits the viability of multiple B-cell acute lymphoblastic leukemia (B-ALL) cell lines with nanomolar potency and induces apoptosis in MV4-11 cells. At 50 mg/kg for 20 days, STF-118804 has been shown to improve survival in an orthotopic xenotransplant model of high-risk ALL in mice. It has also been shown to target leukemia stem cells.More related product prices
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