Sanggenon C
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- $117 - $2400
- Product name: Sanggenon C
- CAS: 80651-76-9
- MF: C40H36O12
- MW: 708.71
- EINECS:
- MDL Number:MFCD32004761
- Synonyms:sanggenone;Sanggenon C;(5aR,10aS)-2-[6β-(2,4-Dihydroxybenzoyl)-5α-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexene-1β-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-butenyl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;2-[(1S)-6β-(2,4-Dihydroxybenzoyl)-5α-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexene-1β-yl]-5a,10a-dihydro-1,3,8,10aβ-tetrahydroxy-5aβ-(3-methyl-2-butenyl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;Sanggenone C;(5aR,10aS)-2-[(1S,5S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-buten-1-yl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;11H-Benzofuro[3,2-b][1]benzopyran-11-one, 2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-buten-1-yl)-, (5aR,10aS)-;(5aR,10aS)-2-((1S,2R,3S)-2-(2,4-Dihydroxybenzoyl)-2',4'-dihydroxy-5-methyl-1,2,3,6-tetrahydro-[1,1'-biphenyl]-3-yl)-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-en-1-yl)-5a,10a-dihydro-11H-benzofuro[3,2-b]chromen-11-one
29 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mlx10mM(inDMSO)
- 1mg
- 2.5mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 1000mg
- ManufacturerAK Scientific
- Product number8253AH
- Product descriptionSanggenoneC
- Packaging10mg
- Price$1126
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2564
- Product description2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-enyl)-[1]benzofuro[3,2-b]chromen-11-one
- Packaging20mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN99593
- Product descriptionSanggenoneC
- Packaging20mg
- Price$383
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2421
- Product descriptionSanggenone C
- Packaging1mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2421
- Product descriptionSanggenone C
- Packaging20mg
- Price$790
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594266
- Product descriptionSanggenon C
- Packaging20mg
- Price$841.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594266
- Product descriptionSanggenon C
- Packaging10mg
- Price$596.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1689928
- Product descriptionSanggenon C 99.76%(Mayvarybetweenbatches)
- Packaging50mg
- Price$780
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1689928
- Product descriptionSanggenon C 99.76%(Mayvarybetweenbatches)
- Packaging200mg
- Price$1410
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1689928
- Product descriptionSanggenon C 99.76%(Mayvarybetweenbatches)
- Packaging100mg
- Price$1030
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1689928
- Product descriptionSanggenon C 99.76%(Mayvarybetweenbatches)
- Packaging10mg
- Price$340
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1689928
- Product descriptionSanggenon C 99.76%(Mayvarybetweenbatches)
- Packaging1mlx10mM(inDMSO)
- Price$340
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1689928
- Product descriptionSanggenon C 99.76%(Mayvarybetweenbatches)
- Packaging25mg
- Price$560
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb105480
- Product descriptionSanggenon C >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1689928
- Product descriptionSanggenon C 99.76%(Mayvarybetweenbatches)
- Packaging5mg
- Price$240
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1689928
- Product descriptionSanggenon C 99.76%(Mayvarybetweenbatches)
- Packaging1mg
- Price$130
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8253AH | SanggenoneC | 10mg | $1126 | 2021-12-16 | Buy |
| ApexBio Technology | N2564 | 2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-enyl)-[1]benzofuro[3,2-b]chromen-11-one | 20mg | $200 | 2021-12-16 | Buy |
| Arctom | CFN99593 | SanggenoneC | 20mg | $383 | 2021-12-16 | Buy |
| AvaChem | 2421 | Sanggenone C | 1mg | $190 | 2021-12-16 | Buy |
| AvaChem | 2421 | Sanggenone C | 20mg | $790 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594266 | Sanggenon C | 20mg | $841.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594266 | Sanggenon C | 10mg | $596.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb1689928 | Sanggenon C 99.76%(Mayvarybetweenbatches) | 50mg | $780 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1689928 | Sanggenon C 99.76%(Mayvarybetweenbatches) | 200mg | $1410 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1689928 | Sanggenon C 99.76%(Mayvarybetweenbatches) | 100mg | $1030 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1689928 | Sanggenon C 99.76%(Mayvarybetweenbatches) | 10mg | $340 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1689928 | Sanggenon C 99.76%(Mayvarybetweenbatches) | 1mlx10mM(inDMSO) | $340 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1689928 | Sanggenon C 99.76%(Mayvarybetweenbatches) | 25mg | $560 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb105480 | Sanggenon C >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb1689928 | Sanggenon C 99.76%(Mayvarybetweenbatches) | 5mg | $240 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1689928 | Sanggenon C 99.76%(Mayvarybetweenbatches) | 1mg | $130 | 2026-05-06 | Buy |
Properties
Melting point :> 240°C (dec.)
Boiling point :995.5±65.0 °C(Predicted)
Density :1.512
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Acetone (Slightly), Methanol (Slightly)
pka :6.61±0.60(Predicted)
form :Solid
color :Yellow
InChIKey :XETHJOZXBVWLLM-HUKCQOFTSA-N
SMILES :[C@@]12(C/C=C(/C)\C)C3=CC=C(O)C=C3O[C@]1(O)C(=O)C1=C(O)C([C@@H]3[C@H](C(=O)C4=CC=C(O)C=C4O)[C@@H](C4=CC=C(O)C=C4O)CC(C)=C3)=C(O)C=C1O2
Boiling point :995.5±65.0 °C(Predicted)
Density :1.512
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Acetone (Slightly), Methanol (Slightly)
pka :6.61±0.60(Predicted)
form :Solid
color :Yellow
InChIKey :XETHJOZXBVWLLM-HUKCQOFTSA-N
SMILES :[C@@]12(C/C=C(/C)\C)C3=CC=C(O)C=C3O[C@]1(O)C(=O)C1=C(O)C([C@@H]3[C@H](C(=O)C4=CC=C(O)C=C4O)[C@@H](C4=CC=C(O)C=C4O)CC(C)=C3)=C(O)C=C1O2
Safety Information
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Description
Sanggenone C is a flavonoid that has been found in mulberry bark and has diverse biological activities. It inhibits TNF-α- or IL-1β-induced polymorphonuclear leukocyte (PMN) adhesion to human synovial cells (HSCs; IC50s = 27.29 and 54.43 nM, respectively), as well as inhibits NF-κB activation in HSCs. Sanggenone C induces apoptosis and production of reactive oxygen species (ROS) in HT-29 cells when used at concentrations ranging from 10 to 40 μM. It decreases cell viability of HT-29 cells in vitro and reduces tumor growth in an HT-29 mouse xenograft model when administered at a dose of 10 mg/kg. Sanggenone C increases vertebrate column bone mineralization in a zebrafish model of prednisone-induced osteoporosis. It also attenuates cardiac hypertrophy and fibrosis and reduces activation of nuclear factor of activated T cells 2 (NFAT2) in a mouse model of pressure overload-induced cardiac hypertrophy.Related product price
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