Shikonin
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- $11 - $2245.7
- Product name: Shikonin
- CAS: 517-89-5
- MF: C16H16O5
- MW: 288.3
- EINECS:
- MDL Number:MFCD00075680
- Synonyms:5,8-Dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione;Tokyo Violet;(R)-5,8-Dihydroxy-2-(1-hydroxy-4-Methylpent-3-en-1-yl)naphthalene-1,4-dione;SHIKONIN(AS);Shikonin, froM Arnebia sp.;(-)-ShikoninChina;Shikonine;Shikonin 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione
49 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0487-M050
- Product descriptionShikonin ≥98%(HPLC)
- Packaging50mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI664
- Product descriptionShikonin
- Packaging10mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI664
- Product descriptionShikonin
- Packaging50mg
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA706788
- Product description(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97%
- Packaging1mg
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA706788
- Product description(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97%
- Packaging10mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA706788
- Product description(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97%
- Packaging25mg
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA706788
- Product description(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97%
- Packaging50mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA706788
- Product description(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97%
- Packaging100mg
- Price$118
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA706788
- Product description(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97%
- Packaging250mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA706788
- Product description(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97%
- Packaging1g
- Price$530
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0000036
- Product descriptionSHIKONIN 95.00%
- Packaging5MG
- Price$429.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0000036
- Product descriptionSHIKONIN 95.00%
- Packaging10MG
- Price$459
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0323
- Product descriptionShikonin
- Packaging10mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0323
- Product descriptionShikonin
- Packaging50mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0323
- Product descriptionShikonin
- Packaging100mg
- Price$379
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN92622
- Product descriptionShikonine ≥98%
- Packaging20mg
- Price$70
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0487-M050 | Shikonin ≥98%(HPLC) | 50mg | $160 | 2021-12-16 | Buy |
| AK Scientific | I664 | Shikonin | 10mg | $67 | 2021-12-16 | Buy |
| AK Scientific | I664 | Shikonin | 50mg | $188 | 2021-12-16 | Buy |
| Ambeed | A706788 | (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97% | 1mg | $11 | 2021-12-16 | Buy |
| Ambeed | A706788 | (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97% | 10mg | $35 | 2021-12-16 | Buy |
| Ambeed | A706788 | (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97% | 25mg | $58 | 2021-12-16 | Buy |
| Ambeed | A706788 | (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97% | 50mg | $85 | 2021-12-16 | Buy |
| Ambeed | A706788 | (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97% | 100mg | $118 | 2021-12-16 | Buy |
| Ambeed | A706788 | (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97% | 250mg | $201 | 2021-12-16 | Buy |
| Ambeed | A706788 | (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione 97% | 1g | $530 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0000036 | SHIKONIN 95.00% | 5MG | $429.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0000036 | SHIKONIN 95.00% | 10MG | $459 | 2021-12-16 | Buy |
| Apolloscientific | BISN0323 | Shikonin | 10mg | $77 | 2021-12-16 | Buy |
| Apolloscientific | BISN0323 | Shikonin | 50mg | $232 | 2021-12-16 | Buy |
| Apolloscientific | BISN0323 | Shikonin | 100mg | $379 | 2021-12-16 | Buy |
| Arctom | CFN92622 | Shikonine ≥98% | 20mg | $70 | 2021-12-16 | Buy |
Properties
Melting point :148℃
Boiling point :567.4±50.0 °C(Predicted)
Density :1.373±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO : ≥ 31 mg/mL (107.53 mM);
pka :7.34±0.20(Predicted)
form :Red crystalline solid.
color :Brown
LogP :4.350 (est)
CAS DataBase Reference :517-89-5(CAS DataBase Reference)
Boiling point :567.4±50.0 °C(Predicted)
Density :1.373±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO : ≥ 31 mg/mL (107.53 mM);
pka :7.34±0.20(Predicted)
form :Red crystalline solid.
color :Brown
LogP :4.350 (est)
CAS DataBase Reference :517-89-5(CAS DataBase Reference)
Safety Information
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Description
Shikonin is a naturally occurring naphthoquinine isolated from the dried root of L. erythrorhizon, an herb used in traditional Chinese medicine. It increases glucose uptake by adipocytes and myocytes and inhibits the activity of phosphatase and tensin homolog (PTEN; IC50 = 2.7 μM). It inhibits glycolysis in cancer cells by inhibiting tumor-specific pyruvate kinase M2 (IC50 = 0.3 μM). Shikonin induces cell death consistent with necroptosis in MCF-7 and HEK293 cancer cell lines. It inhibits leukocyte migration, downregulates chemokine receptor expression, and inhibits HIV-1 replication at nanomolar concentrations. Shikonin exhibits anti-inflammatory activity, reducing joint swelling and cartilage destruction in a mouse model of collagen-induced arthritis.Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Greenpure Biopharma CO.,Ltd
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.
Shandong chuangyingchemical Co., Ltd.
![5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione](https://img.chemicalbook.com/ProductImageEN/2018-12/small/027035a7-de5d-4298-bea1-9acd2fce4903.png){kind=small}