Simvastatin
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- $5 - $4900
- Product name: Simvastatin
- CAS: 79902-63-9
- MF: C25H38O5
- MW: 418.57
- EINECS:616-751-8
- MDL Number:MFCD00072007
- Synonyms:(1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste ;7-beta,8-beta(2s*,4s*),8a-beta))-alph ;[1S-[1α，3α，7β，8β(2S^<*>^，4S^<*>^)，8αβ]-2，2-Dimethylbutanoic acid 1，2，3，7，8，8α-hexahydro-3，7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-y1)ethyl]-1-naphthyl ester;Lodaiès;Butanoic acid, 2,2-dimethyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro- 4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1-alpha,3-alpha,7- beta,8-beta(2S*,4S*),8a-beta));[8-[2-(4-Hydroxy-6-oxo-tetrahydropyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]2,2-dimethylbutanoate;2,2-Dimethylbutyric acid (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalene-1-yl ester;(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethylbutanoate
131 prices
Selected condition：
Brand
- aablocks
- Adipogen Life Sciences
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Aronis compounds
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- s0650000
- y0002069
- 20mg
- 10mM*1mLinDMSO
- 500mg
- 1.00g
- 5.00g
- 50g
- 1kg
- 50
- 250g
- 1000g
- 1 g
- 5 mg
- 5 g
- 200 mg
- 5MG
- 10mg
- 25mg
- 50mg
- 10mM(1mLinDMSO)
- 100mg
- 10mM(in 1mL DMSO)
- 200mg
- 250mg
- 1g
- 5g
- 10g
- 10mM(in1mLDMSO)
- 25g
- 100g
- 500g
- Manufactureraablocks
- Product numberAA00327R
- Product descriptionSimvastatin 98%
- Packaging100mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00327R
- Product descriptionSimvastatin 98%
- Packaging5g
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00327R
- Product descriptionSimvastatin 98%
- Packaging1g
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00327R
- Product descriptionSimvastatin 98%
- Packaging10g
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00327R
- Product descriptionSimvastatin 98%
- Packaging25g
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00327R
- Product descriptionSimvastatin ≥97%(HPLC)
- Packaging100g
- Price$132
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00327R
- Product descriptionSimvastatin 98%
- Packaging500g
- Price$513
- Updated2026-05-28
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0052-M010
- Product descriptionSimvastatin ≥98%(HPLC)
- Packaging10mg
- Price$25
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0052-M050
- Product descriptionSimvastatin ≥98%(HPLC)
- Packaging50mg
- Price$45
- Updated2026-05-06
- Buy
- ManufacturerAHH
- Product numberAPI-1626
- Product descriptionSimvastatin 97%
- Packaging1g
- Price$260
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberJ93930
- Product descriptionSimvastatin 95%
- Packaging100g
- Price$191
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberG293
- Product descriptionSimvastatin 98%(HPLC)
- Packaging100g
- Price$255
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10128
- Product descriptionSimvastatin 99%(HPLC)
- Packaging1g
- Price$479
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberG293
- Product descriptionSimvastatin 98%(HPLC)
- Packaging5g
- Price$30
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10128
- Product descriptionSimvastatin 99%(HPLC)
- Packaging25mg
- Price$42
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ93930
- Product descriptionSimvastatin 95%
- Packaging5g
- Price$23
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00327R | Simvastatin 98% | 100mg | $8 | 2026-05-28 | Buy |
| aablocks | AA00327R | Simvastatin 98% | 5g | $12 | 2026-05-28 | Buy |
| aablocks | AA00327R | Simvastatin 98% | 1g | $10 | 2026-05-28 | Buy |
| aablocks | AA00327R | Simvastatin 98% | 10g | $23 | 2026-05-28 | Buy |
| aablocks | AA00327R | Simvastatin 98% | 25g | $36 | 2026-05-28 | Buy |
| aablocks | AA00327R | Simvastatin ≥97%(HPLC) | 100g | $132 | 2026-05-28 | Buy |
| aablocks | AA00327R | Simvastatin 98% | 500g | $513 | 2026-05-28 | Buy |
| Adipogen Life Sciences | AG-CN2-0052-M010 | Simvastatin ≥98%(HPLC) | 10mg | $25 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0052-M050 | Simvastatin ≥98%(HPLC) | 50mg | $45 | 2026-05-06 | Buy |
| AHH | API-1626 | Simvastatin 97% | 1g | $260 | 2026-05-26 | Buy |
| AK Scientific | J93930 | Simvastatin 95% | 100g | $191 | 2026-06-04 | Buy |
| AK Scientific | G293 | Simvastatin 98%(HPLC) | 100g | $255 | 2026-06-04 | Buy |
| AK Scientific | J10128 | Simvastatin 99%(HPLC) | 1g | $479 | 2026-06-04 | Buy |
| AK Scientific | G293 | Simvastatin 98%(HPLC) | 5g | $30 | 2026-06-04 | Buy |
| AK Scientific | J10128 | Simvastatin 99%(HPLC) | 25mg | $42 | 2026-06-04 | Buy |
| AK Scientific | J93930 | Simvastatin 95% | 5g | $23 | 2026-06-04 | Buy |
Properties
Melting point :127-132 °C (lit.)
alpha :D25 +292° (c = 0.5% in acetonitrile)
Boiling point :564.9±50.0 °C(Predicted)
Density :1.11±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :13.49±0.40(Predicted)
form :solid
color :white
optical activity :[α]/D +275±25°, c = 1 in acetonitrile
Merck :14,8539
Henry's Law Constant :3.5×104 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :2
Stability :Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :RYMZZMVNJRMUDD-HGQWONQESA-N
SMILES :[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
CAS DataBase Reference :79902-63-9(CAS DataBase Reference)
NIST Chemistry Reference :Simvastatin(79902-63-9)
EPA Substance Registry System :Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester (79902-63-9)
alpha :D25 +292° (c = 0.5% in acetonitrile)
Boiling point :564.9±50.0 °C(Predicted)
Density :1.11±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :13.49±0.40(Predicted)
form :solid
color :white
optical activity :[α]/D +275±25°, c = 1 in acetonitrile
Merck :14,8539
Henry's Law Constant :3.5×104 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :2
Stability :Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :RYMZZMVNJRMUDD-HGQWONQESA-N
SMILES :[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
CAS DataBase Reference :79902-63-9(CAS DataBase Reference)
NIST Chemistry Reference :Simvastatin(79902-63-9)
EPA Substance Registry System :Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester (79902-63-9)
Safety Information
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| Signal word: | Warning | ||||||||||||
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Description
Simvastatin is an HMGCR (HMG-CoA reductase) inhibitor with anti-proliferative properties. This compound has been shown to modulate purified bovine pituitary 20 S proteasome via mild stimulation of chymotrypsin-like activity and inhibition of peptidylglutamylpeptide hydrolyzing activity. Mechanistic studies suggest that Simvastatin decreases CDK4 and CDK2 kinase activities and represses high glucose-induced Rho A (Rho GTPase)/p21 signaling in mesangial cells. Simvastatin also potentiates apoptosis in human myeloid leukemia cells via the suppression of TNF-induced NF-κB activation (IC50 ~ 13 M).More related product prices
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Suppliers and manufacturers
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