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ChemicalBook >> CAS DataBase List >> TC ASK 10

TC ASK 10

TC ASK 10 price.
  • $36 - $2647
  • Product name: TC ASK 10
  • CAS: 1005775-56-3
  • MF: C21H22ClN5O
  • MW: 395.89
  • EINECS:
  • MDL Number:MFCD26792581
  • Synonyms:TC ASK 10;ASK1 Inhibitor 10;4-tert-butyl-N-(6-imidazol-1-ylimidazo[1,2-a]pyridin-2-yl)benzamide:hydrochloride;4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride;Apoptosis,ASK1,oral,MAP3K,bioavailability,TC ASK-10,TC ASK10,Inhibitor,pharmacokinetic,JNK,TC ASK 10,p38,inhibit,selective,MAP kinase kinase kinase, MEKK, MAPKKK,Phosphorylation;N-(6-(1H-Imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl)-4-(tert-butyl)benzamide dihydrochloride;TC ASK 10, 10 mM in DMSO
50 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 50
  • 10mg
  • 2x10mg
  • 25mg
  • 50mg
  • 10mM*1mLinDMSO(Solution)
  • 100mg
  • 200mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • Manufactureraablocks
  • Product numberAA0096UD
  • Product descriptionASK1 Inhibitor 10 ≥95%
  • Packaging1mg
  • Price$36
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0096UD
  • Product descriptionASK1 Inhibitor 10
  • Packaging5mg
  • Price$87
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0096UD
  • Product descriptionASK1 Inhibitor 10
  • Packaging10mg
  • Price$127
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0096UD
  • Product descriptionASK1 Inhibitor 10 99%
  • Packaging25mg
  • Price$209
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0096UD
  • Product descriptionASK1 Inhibitor 10
  • Packaging50mg
  • Price$351
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0096UD
  • Product descriptionASK1 Inhibitor 10
  • Packaging100mg
  • Price$494
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0096UD
  • Product descriptionASK1 Inhibitor 10
  • Packaging200mg
  • Price$647
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226395
  • Product descriptionTC ASK 10 97.00%
  • Packaging100MG
  • Price$710
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226395
  • Product descriptionTC ASK 10 97.00%
  • Packaging25MG
  • Price$315
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number7949DT
  • Product descriptionTCAsk10
  • Packaging10mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number7949DT
  • Product descriptionTCAsk10
  • Packaging25mg
  • Price$648
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5728
  • Product descriptionTC ASK 10
  • Packaging25mg
  • Price$680
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5728
  • Product descriptionTC ASK 10
  • Packaging50mg
  • Price$1568
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5728
  • Product descriptionTC ASK 10
  • Packaging10mg
  • Price$295
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5728
  • Product descriptionTC ASK 10
  • Packaging1mg
  • Price$50
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5728
  • Product descriptionTC ASK 10
  • Packaging5mg
  • Price$180
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0096UD ASK1 Inhibitor 10 ≥95% 1mg $36 2026-05-28 Buy
aablocks AA0096UD ASK1 Inhibitor 10 5mg $87 2026-05-28 Buy
aablocks AA0096UD ASK1 Inhibitor 10 10mg $127 2026-05-28 Buy
aablocks AA0096UD ASK1 Inhibitor 10 99% 25mg $209 2026-05-28 Buy
aablocks AA0096UD ASK1 Inhibitor 10 50mg $351 2026-05-28 Buy
aablocks AA0096UD ASK1 Inhibitor 10 100mg $494 2026-05-28 Buy
aablocks AA0096UD ASK1 Inhibitor 10 200mg $647 2026-05-28 Buy
ACHEMBLOCK Y226395 TC ASK 10 97.00% 100MG $710 2026-05-27 Buy
ACHEMBLOCK Y226395 TC ASK 10 97.00% 25MG $315 2026-05-27 Buy
AK Scientific 7949DT TCAsk10 10mg $336 2021-12-16 Buy
AK Scientific 7949DT TCAsk10 25mg $648 2021-12-16 Buy
ApexBio Technology B5728 TC ASK 10 25mg $680 2026-05-06 Buy
ApexBio Technology B5728 TC ASK 10 50mg $1568 2026-05-06 Buy
ApexBio Technology B5728 TC ASK 10 10mg $295 2026-05-06 Buy
ApexBio Technology B5728 TC ASK 10 1mg $50 2026-05-06 Buy
ApexBio Technology B5728 TC ASK 10 5mg $180 2026-05-06 Buy

Properties

Melting point :>270° (dec.)
storage temp. :Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ASK1 inhibitor 10 is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1; IC50 = 14 nM). It is selective for ASK1 over ASK2 (IC50 = 510 nM) as well as MEKK1, TAK-1, IKKβ, ERK1, JNK1, p38α, GSK3β, PKCθ, and B-RAF (IC50s = >10,000 nM for all). It inhibits streptozotocin-induced increases in JNK and p38 phosphorylation in INS-1 pancreatic β cells in a concentration-dependent manner.