TC-H 106
|
- $23 - $1700
- Product name: TC-H 106
- CAS: 937039-45-7
- MF: C20H25N3O2
- MW: 339.43
- EINECS:
- MDL Number:MFCD17010287
- Synonyms:TC-H 106;Pimelic Diphenylamide 106;Compound 106;Inhibitor 106;N1-(2-Aminophenyl)-N7-(4-methylphenyl)-heptanediamide;RGFA 8;N1-(2-aminophenyl)-N8-p-tolyloctanediamide;Histone Deacetylase Inhibitor VII, 106
78 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 25.00mg
- 10mM*1mLinDMSO(Solution)
- 50.00mg
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 10
- 50
- 100.00mg
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00GT8U
- Product descriptionN1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98%
- Packaging1mg
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8U
- Product descriptionN1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98%
- Packaging5mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8U
- Product descriptionN1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98%
- Packaging10mg
- Price$34
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8U
- Product descriptionN1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98%
- Packaging25mg
- Price$41
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8U
- Product descriptionN1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98%
- Packaging50mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8U
- Product descriptionN1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98%
- Packaging100mg
- Price$70
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8U
- Product descriptionN1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 99%
- Packaging250mg
- Price$163
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8U
- Product descriptionN1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 99%
- Packaging1g
- Price$435
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33903
- Product descriptionTC-H 106 98%
- Packaging100MG
- Price$185
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33903
- Product descriptionTC-H 106 98%
- Packaging25MG
- Price$55
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33903
- Product descriptionTC-H 106 98%
- Packaging1G
- Price$750
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1900AH
- Product descriptionN1-(2-Aminophenyl)-N7-(4-methylphenyl)-heptanediamide
- Packaging50mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA301260
- Product descriptionPimelic Diphenylamide 106 98+%
- Packaging100mg
- Price$157
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA301260
- Product descriptionPimelic Diphenylamide 106 98+%
- Packaging250mg
- Price$264
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA301260
- Product descriptionPimelic Diphenylamide 106 98+%
- Packaging1g
- Price$637
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA301260
- Product descriptionPimelic Diphenylamide 106 98+%
- Packaging5mg
- Price$38
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GT8U | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98% | 1mg | $23 | 2026-05-28 | Buy |
| aablocks | AA00GT8U | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98% | 5mg | $28 | 2026-05-28 | Buy |
| aablocks | AA00GT8U | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98% | 10mg | $34 | 2026-05-28 | Buy |
| aablocks | AA00GT8U | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98% | 25mg | $41 | 2026-05-28 | Buy |
| aablocks | AA00GT8U | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98% | 50mg | $49 | 2026-05-28 | Buy |
| aablocks | AA00GT8U | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 98% | 100mg | $70 | 2026-05-28 | Buy |
| aablocks | AA00GT8U | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 99% | 250mg | $163 | 2026-05-28 | Buy |
| aablocks | AA00GT8U | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide 99% | 1g | $435 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33903 | TC-H 106 98% | 100MG | $185 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33903 | TC-H 106 98% | 25MG | $55 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33903 | TC-H 106 98% | 1G | $750 | 2026-05-27 | Buy |
| AK Scientific | 1900AH | N1-(2-Aminophenyl)-N7-(4-methylphenyl)-heptanediamide | 50mg | $209 | 2021-12-16 | Buy |
| Ambeed | A301260 | Pimelic Diphenylamide 106 98+% | 100mg | $157 | 2021-12-16 | Buy |
| Ambeed | A301260 | Pimelic Diphenylamide 106 98+% | 250mg | $264 | 2021-12-16 | Buy |
| Ambeed | A301260 | Pimelic Diphenylamide 106 98+% | 1g | $637 | 2021-12-16 | Buy |
| Ambeed | A301260 | Pimelic Diphenylamide 106 98+% | 5mg | $38 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
form :Yellow solid
color :white to beige
InChI :1S/C20H25N3O2/c1-15-11-13-16(14-12-15)22-19(24)9-3-2-4-10-20(25)23-18-8-6-5-7-17(18)21/h5-8,11-14H,2-4,9-10,21H2,1H3,(H,22,24)(H,23,25)
InChIKey :WTKBRPXPNAKVEQ-UHFFFAOYSA-N
SMILES :N(c2c(cccc2)N)C(=O)CCCCCC(=O)Nc1ccc(cc1)C
solubility :DMSO: ≥15mg/mL
form :Yellow solid
color :white to beige
InChI :1S/C20H25N3O2/c1-15-11-13-16(14-12-15)22-19(24)9-3-2-4-10-20(25)23-18-8-6-5-7-17(18)21/h5-8,11-14H,2-4,9-10,21H2,1H3,(H,22,24)(H,23,25)
InChIKey :WTKBRPXPNAKVEQ-UHFFFAOYSA-N
SMILES :N(c2c(cccc2)N)C(=O)CCCCCC(=O)Nc1ccc(cc1)C
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases (HDACs). Unlike the HDAC inhibitor suberoylanilide hydroamic acid, which has a fast-on/fast-off HDAC binding rate, pimelic diphenylamide 106 progressively binds HDACs and remains bound after wash-out. As a result, the IC50 of pimelic diphenylamide 106 decreases over time. With prolonged preincubation (1-3 hours), pimelic diphenylamide inhibits the class I HDACs (IC50 = 150, 760, 370, and 5,000 nM for HDAC1, 2, 3, and 8, respectively) but not the class II HDACs (IC50 > 180 μM for HDAC4, 5, and 7). Pimelic diphenylamide 106 and related benzamide HDAC inhibitors may have therapeutic value in Friedrich’s ataxia and Huntington’s disease, in part due to their low animal toxicity.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Zibo Hangyu Biotechnology Development Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited
