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ChemicalBook >> CAS DataBase List >> THZ1

THZ1

$36 - $2100
Product name: THZ1
CAS: 1604810-83-4
MF: C31H28ClN7O2
MW: 566.05
EINECS:
MDL Number:MFCD28167785
Synonyms:(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide THZ1;THZ1;N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide;(E)-N-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-en;(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide;THZ-1;THZ 1;CDK7 INHIBITOR;THZ1 HY-80013 GTPL8052 SCHEMBL14979765;Benzamide, N-[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-

Price73 Properties Safety Information Description

73 prices

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aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
AvaChem
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
TRC

Package

10mM*1mLinDMSO(Solution)
2mg
500μg
10mM*1mLinDMSO(Solid+Solvent)
10mM*1mLinDMSO
2.5mg
250mg
10mM(in1mLDMSO)
1mg
5mg
10mg
25mg
50mg
100mg
1G

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide ≥95%
Packaging1mg
Price$70
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging5mg
Price$85
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging10mg
Price$132
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging25mg
Price$212
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging50mg
Price$316
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging100mg
Price$419
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberQ70020
Product description(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%
Packaging100MG
Price$550
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ70020
Product description(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%
Packaging1G
Price$1875
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ70020
Product description(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%
Packaging25MG
Price$195
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number7540DW
Product descriptionCID73602827
Packaging10mg
Price$364
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA8882
Product descriptionTHZ1
Packaging25mg
Price$300
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB4736
Product descriptionTHZ1 Hydrochloride
Packaging25mg
Price$300
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA8882
Product descriptionTHZ1
Packaging10mg
Price$135
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB4736
Product descriptionTHZ1Hydrochloride
Packaging10mg
Price$150
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB4736
Product descriptionTHZ1 Hydrochloride
Packaging10mg
Price$150
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA8882
Product descriptionTHZ1
Packaging10mM(in1mLDMSO)
Price$90
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide ≥95%	1mg	$70	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	5mg	$85	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	10mg	$132	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	25mg	$212	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	50mg	$316	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	100mg	$419	2026-05-28	Buy
ACHEMBLOCK	Q70020	(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%	100MG	$550	2026-05-27	Buy
ACHEMBLOCK	Q70020	(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%	1G	$1875	2026-05-27	Buy
ACHEMBLOCK	Q70020	(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%	25MG	$195	2026-05-27	Buy
AK Scientific	7540DW	CID73602827	10mg	$364	2021-12-16	Buy
ApexBio Technology	A8882	THZ1	25mg	$300	2026-05-06	Buy
ApexBio Technology	B4736	THZ1 Hydrochloride	25mg	$300	2026-05-06	Buy
ApexBio Technology	A8882	THZ1	10mg	$135	2026-05-06	Buy
ApexBio Technology	B4736	THZ1Hydrochloride	10mg	$150	2021-12-16	Buy
ApexBio Technology	B4736	THZ1 Hydrochloride	10mg	$150	2026-05-06	Buy
ApexBio Technology	A8882	THZ1	10mM(in1mLDMSO)	$90	2026-05-06	Buy

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Properties

Density :1.379±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥28.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Powder
pka :12.94±0.70(Predicted)
color :Off-white to yellow
InChIKey :OBJNFLYHUXWUPF-IZZDOVSWSA-N
SMILES :C(NC1=CC=CC(NC2=NC=C(Cl)C(C3C4=C(NC=3)C=CC=C4)=N2)=C1)(=O)C1=CC=C(NC(=O)/C=C/CN(C)C)C=C1

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

THZ1 is a covalent cyclin-dependent kinases 7 (CDK7) inhibitor. It has the ability to target a remote cysteine residue located outside of the canonical kinase domain, providing a means of achieving selectivity for CDK7.

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THZ1

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