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ChemicalBook >> CAS DataBase List >> THZ1

THZ1

$40 - $2100
Product name: THZ1
CAS: 1604810-83-4
MF: C31H28ClN7O2
MW: 566.05
EINECS:
MDL Number:MFCD28167785
Synonyms:(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide THZ1;THZ1;N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide;(E)-N-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-en;(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide;THZ-1;THZ 1;CDK7 INHIBITOR;THZ1 HY-80013 GTPL8052 SCHEMBL14979765;Benzamide, N-[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-

Price57 Properties Safety Information Description

57 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
AvaChem
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
TRC

Package

10mM*1mLinDMSO(Solution)
2mg
500μg
10mM*1mLinDMSO(Solid+Solvent)
10mM*1mLinDMSO
2.5mg
250mg
10mM(in1mLDMSO)
1mg
5mg
10mg
25mg
50mg
100mg
1G

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide ≥95%
Packaging1mg
Price$70
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging5mg
Price$85
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging10mg
Price$132
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging25mg
Price$212
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging50mg
Price$316
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001RUZ
Product descriptionN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
Packaging100mg
Price$419
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberQ70020
Product description(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%
Packaging25MG
Price$195
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ70020
Product description(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%
Packaging100MG
Price$550
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ70020
Product description(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%
Packaging1G
Price$1875
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number7540DW
Product descriptionCID73602827
Packaging10mg
Price$364
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA8882
Product descriptionTHZ1
Packaging25mg
Price$300
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB4736
Product descriptionTHZ1 Hydrochloride
Packaging25mg
Price$300
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB4736
Product descriptionTHZ1 Hydrochloride
Packaging10mg
Price$150
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA8882
Product descriptionTHZ1
Packaging10mg
Price$135
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB4736
Product descriptionTHZ1 Hydrochloride
Packaging10mM(in1mLDMSO)
Price$105
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA8882
Product descriptionTHZ1
Packaging10mM(in1mLDMSO)
Price$90
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide ≥95%	1mg	$70	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	5mg	$85	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	10mg	$132	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	25mg	$212	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	50mg	$316	2026-05-28	Buy
aablocks	AA001RUZ	N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide	100mg	$419	2026-05-28	Buy
ACHEMBLOCK	Q70020	(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%	25MG	$195	2026-05-27	Buy
ACHEMBLOCK	Q70020	(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%	100MG	$550	2026-05-27	Buy
ACHEMBLOCK	Q70020	(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide 98%	1G	$1875	2026-05-27	Buy
AK Scientific	7540DW	CID73602827	10mg	$364	2021-12-16	Buy
ApexBio Technology	A8882	THZ1	25mg	$300	2026-05-06	Buy
ApexBio Technology	B4736	THZ1 Hydrochloride	25mg	$300	2026-05-06	Buy
ApexBio Technology	B4736	THZ1 Hydrochloride	10mg	$150	2026-05-06	Buy
ApexBio Technology	A8882	THZ1	10mg	$135	2026-05-06	Buy
ApexBio Technology	B4736	THZ1 Hydrochloride	10mM(in1mLDMSO)	$105	2026-05-06	Buy
ApexBio Technology	A8882	THZ1	10mM(in1mLDMSO)	$90	2026-05-06	Buy

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Properties

Density :1.379±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥28.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Powder
pka :12.94±0.70(Predicted)
color :Off-white to yellow
InChIKey :OBJNFLYHUXWUPF-IZZDOVSWSA-N
SMILES :C(NC1=CC=CC(NC2=NC=C(Cl)C(C3C4=C(NC=3)C=CC=C4)=N2)=C1)(=O)C1=CC=C(NC(=O)/C=C/CN(C)C)C=C1

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

THZ1 is a covalent cyclin-dependent kinases 7 (CDK7) inhibitor. It has the ability to target a remote cysteine residue located outside of the canonical kinase domain, providing a means of achieving selectivity for CDK7.

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Suppliers and manufacturers

Chengdu Celes Technology Co., Ltd Shanghai Boyle Chemical Co., Ltd. Spectrum Chemical Manufacturing Corp. Dalian Meilun Biotech Co., Ltd. Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC EnliPharma Technology Co., Ltd Hangzhou J&H Chemical Co., Ltd. AdooQ Bioscience CHINA Shanghai KaiYuLin pharmaceutical technology co., LTD

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THZ1

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