TIC10
|
- $32 - $1400
- Product name: TIC10
- CAS: 1616632-77-9
- MF: C24H26N4O
- MW: 386.49
- EINECS:-0
- MDL Number:MFCD28118993
- Synonyms:ONC201,TIC10;TIC-10 (ON201);2,4,6,7,8,9-Hexahydro-4-[(2-methylphenyl)methyl]-7-(phenylmethyl)imidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one;TIC10(ONC-201);TIC 10 active isomer;ONC201;7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-on;TIC10
15 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5389
- Product descriptionTIC10
- Packaging100mg
- Price$1053
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8724
- Product descriptionONC201
- Packaging5mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8724
- Product descriptionONC201
- Packaging10mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8724
- Product descriptionONC201
- Packaging50mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8724
- Product descriptionONC201
- Packaging100mg
- Price$475
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16109
- Product descriptionTIC10 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16109
- Product descriptionTIC10 ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16109
- Product descriptionTIC10 ≥98%
- Packaging10mg
- Price$199
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16109
- Product descriptionTIC10 ≥98%
- Packaging25mg
- Price$420
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31003164
- Product descriptionTIC10(ONC-201) 98+%
- Packaging50mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003164
- Product descriptionTIC10(ONC-201) 98+%
- Packaging100mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003164
- Product descriptionTIC10(ONC-201) 98+%
- Packaging250mg
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8868
- Product descriptionTIC10 >98%
- Packaging100mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8868
- Product descriptionTIC10 >98%
- Packaging1g
- Price$1400
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB285480
- Product description7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one
- Packaging50mg
- Price$160
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5389 | TIC10 | 100mg | $1053 | 2021-12-16 | Buy |
| ApexBio Technology | A8724 | ONC201 | 5mg | $63 | 2021-12-16 | Buy |
| ApexBio Technology | A8724 | ONC201 | 10mg | $94 | 2021-12-16 | Buy |
| ApexBio Technology | A8724 | ONC201 | 50mg | $300 | 2021-12-16 | Buy |
| ApexBio Technology | A8724 | ONC201 | 100mg | $475 | 2021-12-16 | Buy |
| Cayman Chemical | 16109 | TIC10 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 16109 | TIC10 ≥98% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 16109 | TIC10 ≥98% | 10mg | $199 | 2024-03-01 | Buy |
| Cayman Chemical | 16109 | TIC10 ≥98% | 25mg | $420 | 2024-03-01 | Buy |
| Crysdot | CD31003164 | TIC10(ONC-201) 98+% | 50mg | $240 | 2021-12-16 | Buy |
| Crysdot | CD31003164 | TIC10(ONC-201) 98+% | 100mg | $360 | 2021-12-16 | Buy |
| Crysdot | CD31003164 | TIC10(ONC-201) 98+% | 250mg | $520 | 2021-12-16 | Buy |
| DC Chemicals | DC8868 | TIC10 >98% | 100mg | $350 | 2021-12-16 | Buy |
| DC Chemicals | DC8868 | TIC10 >98% | 1g | $1400 | 2021-12-16 | Buy |
| TRC | B285480 | 7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one | 50mg | $160 | 2021-12-16 | Buy |
Properties
Boiling point :559.7±60.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 25 mg/ml with warming).
pka :6.38±0.20(Predicted)
form :solid
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChI :InChI=1S/C24H26N4O/c1-18-7-5-6-10-20(18)16-28-23(29)21-17-26(15-19-8-3-2-4-9-19)13-11-22(21)27-14-12-25-24(27)28/h2-10H,11-17H2,1H3
InChIKey :VLULRUCCHYVXOH-UHFFFAOYSA-N
SMILES :C12=NCCN1C1CCN(CC3=CC=CC=C3)CC=1C(=O)N2CC1=CC=CC=C1C
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 25 mg/ml with warming).
pka :6.38±0.20(Predicted)
form :solid
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChI :InChI=1S/C24H26N4O/c1-18-7-5-6-10-20(18)16-28-23(29)21-17-26(15-19-8-3-2-4-9-19)13-11-22(21)27-14-12-25-24(27)28/h2-10H,11-17H2,1H3
InChIKey :VLULRUCCHYVXOH-UHFFFAOYSA-N
SMILES :C12=NCCN1C1CCN(CC3=CC=CC=C3)CC=1C(=O)N2CC1=CC=CC=C1C
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
TIC10 induces the expression of TNF-related apoptosis-inducing ligand (TRAIL) at 1-5 μM in a p53-independent manner. It is orally active, stable, and crosses the blood-brain barrier. The induction of TRAIL results from dual inhibition of Akt and ERK1/2 combined with nuclear translocation of the transcription factor FOXO3a. TIC10 suppresses the growth of orthotopic human glioblastoma multiforme tumors in mice.More related product prices
NYLON 6 Felodipine Imiquimod RESINIFERATOXIN 57226-68-3 Volasertib (BI 6727)Related product price
- NYLON 6
$33-499.41 - Felodipine
$7-1801.47 - Imiquimod
$6-990
Suppliers and manufacturers
career henan chemical co
![4-[5-methyl-4-[(4-methylphenyl)sulfonylmethyl]-1,3-oxazol-2-yl]-N-(pyridin-3-ylmethyl)benzamide](https://img.chemicalbook.com/ProductImageEN/2020-1/small/741ceb00-1510-4d9f-bf96-8720f0596e09.png)
ATK CHEMICAL COMPANY LIMITED
Shanghai Daken Advanced Materials Co.,Ltd
BOC Sciences
HANGZHOU CLAP TECHNOLOGY CO.,LTD
ANHUI WITOP BIOTECH CO., LTD
InvivoChem
HANGZHOU LEAP CHEM CO., LTD.
$1.00 /1KG
4-[5-methyl-4-[(4-methylphenyl)sulfonylmethyl]-1,3-oxazol-2-yl]-N-(pyridin-3-ylmethyl)benzamide CAS:1616632-77-9
4-[5-methyl-4-[(4-methylphenyl)sulfonylmethyl]-1,3-oxazol-2-yl]-N-(pyridin-3-ylmethyl)benzamide CAS:1616632-77-9
