Tanshinone IIA
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- $14 - $1490
- Product name: Tanshinone IIA
- CAS: 568-72-9
- MF: C19H18O3
- MW: 294.34
- EINECS:
- MDL Number:MFCD00238692
- Synonyms:AKOS NCG1-0066;3,8,8-TRIMETHYL-8,9,10,11-TETRAHYDROPHENANTHRO[1,2-B]FURAN-1,2-DIONE;TANSHINONE IIA 98+%;1,6,6-TRIMETHYL-6,7,8,9-TETRAHYDRO-PHENANTHRO[1,2-B]FURAN-10,11-DIONE;TANSHINONE IIA;TANSHINONES IIA;tanshiones ;Tanshionesiia
62 prices
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Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- JR MediChem
- Labseeker
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- Tocris
- TRC
Package
- 5mg
- 20mg
- 25mg
- 10mg
- y0001560
- 10
- 100mg
- 500mg
- 50
- 50mg
- 250mg
- 2g
- 10mM(in 1mL DMSO)
- 1g
- 10g
- 25g
- 15 mg
- ManufacturerAK Scientific
- Product numberS594
- Product descriptionTanshinone IIA
- Packaging10mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberS594
- Product descriptionTanshinone IIA
- Packaging100mg
- Price$449
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010219
- Product descriptionTANSHINONE IIA 95.00%
- Packaging10MG
- Price$656.34
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010219
- Product descriptionTANSHINONE IIA 95.00%
- Packaging100MG
- Price$1318.86
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1846
- Product descriptionTanshinone IIA
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS008074
- Product descriptionTanshinone IIA 97%
- Packaging5mg
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS008074
- Product descriptionTanshinone IIA 97%
- Packaging10mg
- Price$18
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS008074
- Product descriptionTanshinone IIA 97%
- Packaging25mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY052963
- Product descriptionTanshinone IIA ≥98%
- Packaging10mg
- Price$27.27
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS008074
- Product descriptionTanshinone IIA 97%
- Packaging50mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN98952
- Product descriptionTanshinone IIA ≥98%
- Packaging20mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS008074
- Product descriptionTanshinone IIA 97%
- Packaging100mg
- Price$37
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS008074
- Product descriptionTanshinone IIA 97%
- Packaging250mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS008074
- Product descriptionTanshinone IIA 97%
- Packaging1g
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1071
- Product descriptionTanshinone IIA
- Packaging10mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1071
- Product descriptionTanshinone IIA
- Packaging20mg
- Price$39
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | S594 | Tanshinone IIA | 10mg | $68 | 2021-12-16 | Buy |
| AK Scientific | S594 | Tanshinone IIA | 100mg | $449 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010219 | TANSHINONE IIA 95.00% | 10MG | $656.34 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010219 | TANSHINONE IIA 95.00% | 100MG | $1318.86 | 2021-12-16 | Buy |
| ApexBio Technology | N1846 | Tanshinone IIA | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
| Arctom | AS008074 | Tanshinone IIA 97% | 5mg | $14 | 2021-12-16 | Buy |
| Arctom | AS008074 | Tanshinone IIA 97% | 10mg | $18 | 2021-12-16 | Buy |
| Arctom | AS008074 | Tanshinone IIA 97% | 25mg | $23 | 2021-12-16 | Buy |
| Arctom | SY052963 | Tanshinone IIA ≥98% | 10mg | $27.27 | 2021-12-16 | Buy |
| Arctom | AS008074 | Tanshinone IIA 97% | 50mg | $29 | 2021-12-16 | Buy |
| Arctom | CFN98952 | Tanshinone IIA ≥98% | 20mg | $30 | 2021-12-16 | Buy |
| Arctom | AS008074 | Tanshinone IIA 97% | 100mg | $37 | 2021-12-16 | Buy |
| Arctom | AS008074 | Tanshinone IIA 97% | 250mg | $55 | 2021-12-16 | Buy |
| Arctom | AS008074 | Tanshinone IIA 97% | 1g | $163 | 2021-12-16 | Buy |
| AvaChem | 1071 | Tanshinone IIA | 10mg | $29 | 2021-12-16 | Buy |
| AvaChem | 1071 | Tanshinone IIA | 20mg | $39 | 2021-12-16 | Buy |
Properties
Melting point :196.0 to 200.0 °C
Boiling point :480.7±44.0 °C(Predicted)
Density :1.209±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :methanol: soluble5mg/mL, clear, red-orange to red
form :powder, red
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C19H18O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,9H,4-5,8H2,1-3H3
InChIKey :HYXITZLLTYIPOF-UHFFFAOYSA-N
SMILES :O1C=C(C)C2C(=O)C(=O)C3=C(C1=2)C=CC1=C3CCCC1(C)C
LogP :4.925 (est)
CAS DataBase Reference :568-72-9(CAS DataBase Reference)
Boiling point :480.7±44.0 °C(Predicted)
Density :1.209±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :methanol: soluble5mg/mL, clear, red-orange to red
form :powder, red
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C19H18O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,9H,4-5,8H2,1-3H3
InChIKey :HYXITZLLTYIPOF-UHFFFAOYSA-N
SMILES :O1C=C(C)C2C(=O)C(=O)C3=C(C1=2)C=CC1=C3CCCC1(C)C
LogP :4.925 (est)
CAS DataBase Reference :568-72-9(CAS DataBase Reference)
Safety Information
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Description
Tanshinone IIA (TSA) is a major lipophilic component of extracts from the root of S. miltiorrhiza, used widely in Chinese herbal medicine. It has anti-inflammatory activity, inhibiting production of TNF-α, IL-1β, IL-6, NO, INFγ, and expression of iNOS, and IL-12. It blocks human aortic smooth muscle cell migration, inhibits MMP-9 activity, and interferes with PI3K/Akt and ERK1/2 signaling pathways. It is cytotoxic to various cancer cells including A549 lung cancer cells and leukemia cells.Reduction of TSA by NAD(P)H:quinone oxidoreductase (NQO1) generates an unstable intermediate resulting in reactive oxygenase species-mediated apoptotic cell death.Related product price
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Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Biopurify Phytochemicals Ltd.
Nanjing Dolon Biotechnology Co.,Ltd.
Hubei Jusheng Technology Co.,Ltd.
Xi'an Kono chem co., Ltd.,
Shaanxi Pioneer Biotech Co., Ltd .
